Internal Medicine: Endocrinology and Metabolic Diseases

Data

Official data in SubjectManager for the following academic year: 2024-2025

Course director

Number of hours/semester

lectures: 10 hours

practices: 20 hours

seminars: 0 hours

total of: 30 hours

Subject data

  • Code of subject: OAK-EAB-T
  • 2 kredit
  • General Medicine
  • Clinical modul
  • spring
Prerequisites:

OAP-BPR-T finished , OAK-PH2-T parallel , OAK-KBK-T finished

Course headcount limitations

min. 5 – max. 150

Topic

Endocrine and metabolic disorders are common in the population and their incidence is increased continuously. Knowledge of these disorders is essential for the practitioners.

Topics: Disorders of the hypothalamus and pituitary gland, thyroid diseases, problems in the calcium homeostasis, disorders of the adrenal gland, endocrine tumors, obesity, primary and secondary hyperlipoproteinemias.

Lectures

  • 1. Disorders of the hypothalamus and pituitary gland 1 - Nemes Orsolya
  • 2. Disorders of the pituitary gland 2 - Nemes Orsolya
  • 3. Thyroid disorders 1 - Mezősi Emese
  • 4. Thyroid disorders 2 - Mezősi Emese
  • 5. Disorders of the calcium homeostasis, MEN syndromes - Mezősi Emese
  • 6. Disorders of the adrenal gland 1 - Mezősi Emese
  • 7. Disorders of the adrenal gland 2 - Mezősi Emese
  • 8. Weight disorders. - Bajnok László Zoltán
  • 9. Dyslipidemias 1 - Bajnok László Zoltán
  • 10. Dyslipidemias 2 - Bajnok László Zoltán

Practices

  • 1. Disorders of the hypothalamus and pituitary gland 1
  • 2. Disorders of the hypothalamus and pituitary gland 1
  • 3. Disorders of the pituitary gland 2
  • 4. Disorders of the pituitary gland 2
  • 5. Thyroid disorders 1
  • 6. Thyroid disorders 1
  • 7. Thyroid disorders 2
  • 8. Thyroid disorders 2
  • 9. Disorders of the calcium homeostasis, MEN syndromes
  • 10. Disorders of the calcium homeostasis, MEN syndromes
  • 11. Disorders of the adrenal gland 1
  • 12. Disorders of the adrenal gland 1
  • 13. Disorders of the adrenal gland 2
  • 14. Disorders of the adrenal gland 2
  • 15. Weight disorders
  • 16. Weight disorders
  • 17. Dyslipidemias 1
  • 18. Dyslipidemias 1
  • 19. Dyslipidemias 2
  • 20. Dyslipidemias 2

Seminars

Reading material

Obligatory literature

Tierney LM, McPhee SJ, Papadakis MA. Current Medical Diagnosis and Treatment, current edition, Lange/McGraw-Hill, New York, NY.

Literature developed by the Department

presentations are available on the intranet

Notes

no

Recommended literature

www.endotext.org

Harrison's: Principles of Internal Medicine (current edition)

Conditions for acceptance of the semester

nincs

Mid-term exams

Students take a written test during the exam period with the exam topics listed below. The result of the written test gives 80% of the final grade. 5 written exams are scheduled. Performance during the practices in the instruction period and the result of an oral practical exam held during the last two weeks of the instruction period account for 20% of the final grade.

Making up for missed classes

In case of more than 15% of absence from the practices (i.e. more than 2 practices) or more than 15% of absence from all contact hours (lectures and practices counted together) will result in refusal of signature and exclusion from the exam. In such cases students may apply for leniency to the course leader. If the absence exceeds 25%, signature will be automatically refused with no possibility for excuse.

We cannot make a difference between absences with and without acceptable reason.

If a student disturbs the contact hours or the work of the clinical ward, if his behaviour represents a health risk for patients, for groupmates or for himself, he can be excluded from the contact hour and considered to be absent.

An absence may be compensated by attending another group’s practice, which must be authenticated by the tutor (maximum 2 practices).

Exam topics/questions

1. Diagnosis of hypothalamic-pituitary axis

2. Pituitary neoplasms

3. Gigantism and acromegaly

4. Hyperprolactinaemia

5. Hypopituitarism

6. Diabetes insipidus

7. Syndrome of inappropriate ADH section

8. Diagnosis of thyroid disorders

9. Iodine metabolism, iodine deficiency

10. Euthyroid goiter

11. Thyroiditis

12. Hypothyroidism

13. Graves disease

14. Endocrine ophtalmopathy

15. Thyrotoxic crisis

16. Non-immune hyperthyroidism

17. Diagnosis of thyroid nodules

18. Thyroid cancer.

19. Diagnosis of pituitary-adrenal axis

20. Adrenal insufficiency

21. Addison crisis

22. Side effects of chronic corticosteroid treatment

23. Cushing syndrome

24. Primary and secondary hyperaldosteronism

25. Pheochromocytoma

26. Basic and advanced investigations in suspected endocrine hypertension

27. Diagnosis of parathyroid disorders

28. Hyperparathyroidism

29. Hypoparathyroidism

30. Medullary thyroid cancer, multiple endocrine neoplasias

31. Carcinoid

32. Insulinoma

33. Polycystic ovarium syndrome

34. Main parts and processes of lipoprotein metabolism

35. Forms of dyslipidemias

36. Laboratory diagnosis of lipoprotein metabolism and definitions of dyslipidemias

37. Primary hyperlipoproteinemias

38. Secondary dyslipidemias

39. Target values in lipidology

40. Drug treatments of dyslipidemias

41. Indications, contraindications, side effects, and complications of statins

42. Theory and clinical practice of cardio-vascular risk stratification

43. Steps of lifestyle modification therapy

44. Definition and types of obesity and overweight. Methods for their measurements

45. Causes and pathomechanism of obesity and overweight

46. Pathomechanisms of obesity related complications

47. Obesity related complications

48. Lifestyle treatments of obesity and overweight

49. Drug treatment of obesity and overweight. Indications, contraindications, and side effects

50. Invasive treatments of obesity and overweight. Indications, contraindications, and side effects

Examiners

  • Bajnok László Zoltán
  • Biró Katalin
  • Gulyás Erna
  • Mezősi Emese
  • Nemes Orsolya

Instructor / tutor of practices and seminars

  • Bajnok László Zoltán
  • Biró Katalin
  • Mezősi Emese
  • Nemes Orsolya
  • Rajbár Renáta