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Education

Haematopoietic Stem Cell Transplantation

Data

Official data in SubjectManager for the following academic year: 2024-2025

Course director

Number of hours/semester

lectures: 6 hours

practices: 6 hours

seminars: 0 hours

total of: 12 hours

Subject data

  • Code of subject: OAE-OST-T
  • 1 kredit
  • General Medicine
  • Elective modul
  • spring
Prerequisites:

OAK-HAE-T parallel , OAA-EL2-T finished , OAP-PA2-T finished

Course headcount limitations

min. 5 – max. 20

Topic

Basic principles of the hamatopoietic stem cell transplantation (HSCT) including different types and sources of haematopoietic stem cells. The wide ranges of indications of HSCT. Short- and long-term complications.

In the practices, there will be the chance to observe the whole process of stem cell collections, processing and cryopreservation and the transplantation itself.

Lectures

  • 1. Introduction - Alizadeh Hussain
  • 2. Types and indications of transplantation - Alizadeh Hussain
  • 3. Autologous HSCT - Szomor Árpád
  • 4. Allogeneic HSCT - Alizadeh Hussain
  • 5. Immune effector therapies (CAR-T, CAR-NK, BiTE, etc) - Alizadeh Hussain
  • 6. Short- and long term complications - Szomor Árpád

Practices

  • 1. Basic principles of HSCT - Alizadeh Hussain
  • 2. Indications of HSCT and its clinical implications - Alizadeh Hussain
  • 3. Stem cell collections and preservation - Kosztolányi Szabolcs
  • 4. Therapeutic apheresis - Szomor Árpád
  • 5. Therapeutic plasmapheresis - Alizadeh Hussain
  • 6. Summary of HSCT complications including real world patient assessment - Szomor Árpád

Seminars

Reading material

Obligatory literature

Literature developed by the Department

- R. Hoffman (ed.): Hematology, Churchill-Livingstone 2005

- A. V. Hoffbrand, P.A. H. Moss, J. E. Petit (eds.): Essential Haematology, 5th edition, Blackwell Publishing 2006 ISBN 140 5136499

4. A. D.Thomas: Hematopoietic Cell Transplantation (ed.: Blume K.G., Forman S.J., Appelbaum F.R.) Blackwell Publishing Co. 2004

5. Clinical Bone Marrow and Blood stem cell transplantation (ed.: Atkinson K., Champlin R., Ritz J., Fibbe W.E., Ljungman P, Brenner M.K.) Cambridge University Press 2004

Notes

Recommended literature

Conditions for acceptance of the semester

-

Mid-term exams

Maximum 20% absences will be accepted

Making up for missed classes

Max 20%

Exam topics/questions

Multiple choice questions.

Examiners

Instructor / tutor of practices and seminars

  • Alizadeh Hussain
  • Kosztolányi Szabolcs
  • Szomor Árpád
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