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Education

Molecular Medicine

Data

Official data in SubjectManager for the following academic year: 2024-2025

Course director

Number of hours/semester

lectures: 24 hours

practices: 0 hours

seminars: 0 hours

total of: 24 hours

Subject data

  • Code of subject: OTF-MOM-T
  • 2 kredit
  • Biotechnology BSc
  • Optional modul
  • spring
Prerequisites:

-

Course headcount limitations

min. 5 – max. 200

Topic

Short description of the course: The course covers overlapping fields of molecular cell biology and clinical genetics, discusses the significance of molecular genetics in clinical medicine. Main topics: the relationship between genotype and phenotype; human genome and phenome program; mosaicism; microsatellite instability; genomic imprinting; embryo cloning; gene therapy; ethical aspects of molecular medicine.

The main educational task of the subject: The aim of the course is to develop connections between basic science and clinical medicine; to convince students that knowledge of molecular biology is essential to understand the pathomechanism of diseases; to give students the chance to face clinical problems even at the beginning of their medical studies.

Lectures

  • 1. DNA fingerprinting - Szeberényi József
  • 2. DNA fingerprinting - Szeberényi József
  • 3. Gentotype-fenotype; fenotype-genotype - Kosztolányi György
  • 4. Gentotype-fenotype; fenotype-genotype - Kosztolányi György
  • 5. Human genome project - Szeberényi József
  • 6. Human genome project - Szeberényi József
  • 7. Mosaicism - Kosztolányi György
  • 8. Mosaicism - Kosztolányi György
  • 9. Diseases of protein folding - Szeberényi József
  • 10. Diseases of protein folding - Szeberényi József
  • 11. The RNA-world - Szeberényi József
  • 12. The RNA-world - Szeberényi József
  • 13. Non-Mendelian monogenic inheritance - Kosztolányi György
  • 14. Non-Mendelian monogenic inheritance - Kosztolányi György
  • 15. Intracellular antibodies - Szeberényi József
  • 16. Intracellular antibodies - Szeberényi József
  • 17. Cloning - Szeberényi József
  • 18. Cloning - Szeberényi József
  • 19. Molecular cytogenetics - Kosztolányi György
  • 20. Molecular cytogenetics - Kosztolányi György
  • 21. Genetics and environment; epigenetics - Kosztolányi György
  • 22. Genetics and environment; epigenetics - Kosztolányi György
  • 23. Final test - Szeberényi József
  • 24. Final test - Szeberényi József

Practices

Seminars

Reading material

Obligatory literature

None.

Literature developed by the Department

None.

Notes

None.

Recommended literature

Gelehrter-Collins: Principles of Medical Genetics

Cooper-Mausman: The Cell. A Molecular Approach

Conditions for acceptance of the semester

According to the Code of Studies

Mid-term exams

None.

Making up for missed classes

None.

Exam topics/questions

None.

Examiners

Instructor / tutor of practices and seminars

Rólunk