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Education

The Road to Molecular Medicine

Data

Official data in SubjectManager for the following academic year: 2024-2025

Course director

  • Szeberényi József

    emeritus professor,
    Department of Medical Biology and Central Electron Microscope Laboratory

Number of hours/semester

lectures: 12 hours

practices: 0 hours

seminars: 0 hours

total of: 12 hours

Subject data

  • Code of subject: OBF-UMO-T
  • 1 kredit
  • Biotechnology MSc
  • Optional modul
  • autumn
Prerequisites:

-

Course headcount limitations

min. 5 – max. 100

Topic

Molecular Medicine is a field of science that studies the mechanisms of pathogenesis and new possibilities for the diagnosis and therapy of human diseases at the level of molecules (nucleic acids and proteins). This course is designed to discuss the discoveries in molecular cell biology most important for clinical medicine: it will present their scientific background, their impact on medicine, the new perspectives opened by them. The course is closely connected to the compulsory subject Molecular Cell Biology and to the elective course Molecular Medicine.

Lectures

  • 1. Introduction: Cellular pathology and molecular medicine - Szeberényi József
  • 2. The story of DNA - Szeberényi József
  • 3. The story of recombinant DNA technology: Restriction endonucleases - Szeberényi József
  • 4. The story of recombinant DNA technology: Cloning of DNA fragments - Szeberényi József
  • 5. Gene targeting by homologous recombination - Szeberényi József
  • 6. Gene targeting by site-specific endonucleases - Szeberényi József
  • 7. Gene drive - Szeberényi József
  • 8. Genetically modified organisms - Szeberényi József
  • 9. GMO-food: the controversy - Szeberényi József
  • 10. Oligonucleotide therapy - Szeberényi József
  • 11. Gene therapy - Szeberényi József
  • 12. Test - Szeberényi József

Practices

Seminars

Reading material

Obligatory literature

None.

Literature developed by the Department

The course consists of lectures of the board-and-chalk style. Taking notes is recommended.

Notes

None.

Recommended literature

Cooper: The Cell. A Molecular Approach

Conditions for acceptance of the semester

None.

Mid-term exams

Final multiple-choice question-based exam, oral improvement retake.

Making up for missed classes

No possibilities.

Exam topics/questions

None

Examiners

Instructor / tutor of practices and seminars

Rólunk