Reproductive Immunology

Data

Official data in SubjectManager for the following academic year: 2024-2025

Course director

Number of hours/semester

lectures: 24 hours

practices: 0 hours

seminars: 0 hours

total of: 24 hours

Subject data

  • Code of subject: OTF-RPI-T
  • 2 kredit
  • Biotechnology BSc
  • Optional modul
  • both
Prerequisites:

OTV-IMMU-T finished

Exam course:

Course headcount limitations

min. 5 – max. 80

Available as Campus course for . Campus-karok: ETK GYTK TTK

Topic

Immune responses play an important role in various reproductive processes, including ovulation, menstruation, and parturition. Clearly, during pregnancy, when the mother must accept a semi-allogeneic fetus, immune responses also play a very important role. This was first recognized by Medawar in 1953 when the concept of the fetal allograft was presented to explain the immunological relationship between mother and fetus. Since then, the immunology of pregnancy has been the leading subject within reproductive immunology research. The present course provides an update of current knowledge about the so-called `immunological paradox of pregnancy, and the role of the immune system in pregnancy-related complications such as recurrent implantation failure, recurrent pregnancy loss, etc. The course also covers the diagnosis and therapeutic methods developed to overcome immune-related infertility conditions.

Lectures

  • 1.

    Introduction, immune system, and Basic concepts in immunology

    - Ahmadi Hamid
  • 2.

    Introduction, immune system, and Basic concepts in immunology

    - Ahmadi Hamid
  • 3.

    Immunology of reproductive tracts, The alteration of the immune system during the menstrual cycle

    - Ahmadi Hamid
  • 4.

    Immunology of reproductive tracts, The alteration of the immune system during the menstrual cycle

    - Ahmadi Hamid
  • 5.

    Immune system in oocyte development, ovaries, and spermiogenesis

    - Ahmadi Hamid
  • 6.

    Immune system in oocyte development, ovaries, and spermiogenesis

    - Ahmadi Hamid
  • 7.

    The role of seminal plasma in embryo implantation and modulating the immune system

    - Ahmadi Hamid
  • 8.

    The role of seminal plasma in embryo implantation and modulating the immune system

    - Ahmadi Hamid
  • 9.

    Endometrial immune profile and immunologic tolerance in embryo implantation and growth

    - Ahmadi Hamid
  • 10.

    Endometrial immune profile and immunologic tolerance in embryo implantation and growth

    - Ahmadi Hamid
  • 11.

    Maternal immune system in placental progression, successful pregnancy, and fetal birth

    - Ahmadi Hamid
  • 12.

    Maternal immune system in placental progression, successful pregnancy, and fetal birth

    - Ahmadi Hamid
  • 13.

    Tumor immunology and pregnancy, Inflammation, and pregnancy disorders

    - Ahmadi Hamid
  • 14.

    Tumor immunology and pregnancy, Inflammation, and pregnancy disorders

    - Ahmadi Hamid
  • 15.

    Recurrent implantation failure, Recurrent pregnancy loss

    - Ahmadi Hamid
  • 16.

    Recurrent implantation failure, Recurrent pregnancy loss

    - Ahmadi Hamid
  • 17.

    Preeclampsia, Endometriosis, Thin endometrium, and OF

    - Ahmadi Hamid
  • 18.

    Preeclampsia, Endometriosis, Thin endometrium, and OF

    - Ahmadi Hamid
  • 19.

    Diagnosis of immune-related infertility problems

    - Ahmadi Hamid
  • 20.

    Diagnosis of immune-related infertility problems

    - Ahmadi Hamid
  • 21.

    Treatment of immune-related infertility problems (Personalized Medicine in Infertility, Embryo Quality, Endometrial Receptivity Array (ERA), Biomarker Screenings).

    - Ahmadi Hamid
  • 22.

    Treatment of immune-related infertility problems (Personalized Medicine in Infertility, Embryo Quality, Endometrial Receptivity Array (ERA), Biomarker Screenings).

    - Ahmadi Hamid
  • 23.

    Assisted Reproductive Technology (Different types of ART, Health status of ART-conceived babies regarding the immune system, Improvements in ART)

    - Ahmadi Hamid
  • 24.

    Assisted Reproductive Technology (Different types of ART, Health status of ART-conceived babies regarding the immune system, Improvements in ART)

    - Ahmadi Hamid

Practices

Seminars

Reading material

Obligatory literature

Literature developed by the Department

Notes

Recommended literature

Cellular and molecular immunology,10th edition by Abull Abas, Andrew Lichtman, Shiv Pillai

Reproductive Immunology, Basic Concepts by Gil Mor

Conditions for acceptance of the semester

-

Mid-term exams

-

Making up for missed classes

consultation

Exam topics/questions

1.      Introduction, immune system, and Basic concepts in immunology

2.      Immunology of reproductive tracts, The alteration of the immune system during the menstrual cycle

3.      Immune system in oocyte development, ovaries, and spermiogenesis

4.      The role of seminal plasma in embryo implantation and modulating the immune system

5.       Endometrial immune profile and immunologic tolerance in embryo implantation and growth

6.      Maternal immune system in placental progression, successful pregnancy, and fetal birth

7.      Tumor immunology and pregnancy, Inflammation, and pregnancy disorders

8.      Recurrent implantation failure, Recurrent pregnancy loss

9.      Preeclampsia, Endometriosis, Thin endometrium, and OF

10.  Diagnosis of immune-related infertility problems

11.  Treatment of immune-related infertility problems (Personalized Medicine in Infertility, Embryo Quality, Endometrial Receptivity Array (ERA), Biomarker Screenings).

12.  Assisted Reproductive Technology (Different types of ART, Health status of ART-conceived babies regarding the immune system, Improvements in ART)

Examiners

Instructor / tutor of practices and seminars