Pharmaceutical Applied Immunology

Data

Official data in SubjectManager for the following academic year: 2024-2025

Topic

Pharmacist perspective on pharmaceutical products that affect the immune system or function in an immunological manner. The course describes the immunological effect and mechanism of action for various pharmaceutical products (both conventional small molecules and modern macromolecules) with special attention to drugs with direct immune-modulation or sharing common immunological side-effects. The course details which products and drug combinations lead to efficient immune-mediated disease resolution or the development of adverse side-effects due to affecting the immune system. The course also discusses the way drug combinations affect the immune system.

Lectures

• 13.

  The role of certain vitamins (B, C, D, E) in the prevention and therapy of immune-pathologies

  - Bóvári-Biri Judit
• 12. The effect of various conventional and modern vaccines on immune cells - Kvell Krisztián
• 11. The effect of cytostatic drugs on immune cells and molecular processes - Kvell Krisztián
• 10.

  The effect of steroid anti-inflammatory drugs on immune cells and molecular processes

  - Bóvári-Biri Judit
• 9.

  The effect of non-steroid anti-inflammatory drugs on immune cells and molecular processes

  - Bóvári-Biri Judit
• 8. Modulation of immune response in autoimmune diseases through the use of cytokines - Kvell Krisztián
• 7.

  Modulation of immune response in malignant diseases through the use of cytokines

  - Bóvári-Biri Judit
• 5. Modulation of the immune response through monoclonal antibodies in autoimmune inflammatory diseases - Kvell Krisztián
• 6. Production of pharmaceutically relevant cytokines, chemokines and their receptors - Kvell Krisztián
• 3. Modification of antibody-based products – fusion, labeling, radioactive and toxic antibodies - Kvell Krisztián
• 4. Utilization of monoclonal antibodies in cancer therapy – products acting directly on cancer cells or the tumor micro-environment - Kvell Krisztián
• 2. Production of antibody-based products, identification of their products - Kvell Krisztián
• 1. Pharmaceutical products acting on the immune system from a pharmacist perspectiv, course structure, obligations - Kvell Krisztián
• 14.

  The role of certain trace elements (copper, zinc, selenium) in the prevention and therapy of immune-pathologies

  - Bóvári-Biri Judit

Practices

Seminars

• 14. Final consultation seminar - Kvell Krisztián
• 13. Immune-checkpoint therapy (CTLA4, PD1) in certain malignant diseases - Kvell Krisztián
• 12. Immune-checkpoint therapy (CTLA4, PD1), machanism of action, side effects - Kvell Krisztián
• 11.

  Arthritis treatment using macromolecule-based immune therapy (anti-TNFalpha)

  - Garai Kitti
• 10.

  Arthritis treatment using small molecule-based immune therapy (5-ASA)

  - Garai Kitti
• 9.

  Arthritis treatment using macromolecule-based immune therapy (anti-IL6)

  - Garai Kitti
• 7.

  Midterm consultation seminar

  - Garai Kitti
• 8.

  Arthritis treatment using small molecule-based immune therapy (NSAID, steroid)

  - Garai Kitti
• 6. Hemopoietic drugs: mechanism of action, application - Kvell Krisztián
• 4. Immunoglobulin therapy: IVIG application in certain diseases - Kvell Krisztián
• 5. Determination of blood groups with various methods - Kvell Krisztián
• 2.

  Quick-test: pregnancy test

  - Garai Kitti
• 3. Immunoglobulin therapy: IVIG collection, donor validation, pooling - Kvell Krisztián
• 1. Quick-test: Covid test - Kvell Krisztián

Reading material

Obligatory literature

Literature developed by the Department

Lecture and seminar ppt

Notes

Lecture notes, learning materials of the lectures are available on MeetStreet, Moodle

Pharmaceutical Applied Immunology 2019

Recommended literature

Conditions for acceptance of the semester

Successful midterm test.

Mid-term exams

Written test

Making up for missed classes

According to the Code of Studies and Examinations.

Exam topics/questions

MeetStreet, Teams, Moodle

Examiners

• Bánfai Krisztina
• Kvell Krisztián

Instructor / tutor of practices and seminars

• Bánfai Krisztina
• Bóvári-Biri Judit
• Garai Kitti
• Kvell Krisztián