Genetic Background of Gene Manipulation II

Data

Official data in SubjectManager for the following academic year: 2026-2027

Course director

Number of hours/semester

lectures: 14 hours

practices: 0 hours

seminars: 42 hours

total of: 56 hours

Subject data

  • Code of subject: ÚJ_OTV-GGM2_26
  • 7 kredit
  • Biotechnology BSc
  • Specialised Core modul
  • spring semester
Prerequisites:

OTV-BIC2-T finished , ÚJ-OTV-GGM1_26-T finished

Course headcount limitations

min. 1 – max. 999

Topic

The subject expands on the knowledge which was accumulated in the previous semester. Gene mutation, DNA repair mechanisms and transposition, regulation of gene expression, transcriptional and post-transcriptional regulation will be discussed. Finally, epigenetic regulation of gene expression and its consequences will be the final topic.

Lectures

  • 1. Gene mutations - Garai Kitti
  • 2. Replication errors and Base modifications - Garai Kitti
  • 3. Induced mutations induced by chemicals and radiation I. - Garai Kitti
  • 4. Induced mutations induced by chemicals and radiation II. - Garai Kitti
  • 5. Mutations in the background of human diseases I. - Garai Kitti
  • 6. Mutations in the background of human diseases II. - Garai Kitti
  • 7. Transposable elements - Garai Kitti
  • 8. Regulation of gene expression in bacteria - Garai Kitti
  • 9. Regulation of gene expression in Eukaryotes - Garai Kitti
  • 10. Transcriptional regulation in Eukaryotes - Garai Kitti
  • 11. The epigenome - Garai Kitti
  • 12. Regulation of the epigenome - Garai Kitti
  • 13. Epigenetics and diseases - Garai Kitti
  • 14. Epigenetic traits - Garai Kitti

Practices

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Reading material

Obligatory literature

Literature developed by the Department

Own ppt, interactive teaching material

Notes

Recommended literature

Klug et al: Concepts of Genetics 12th Edition

Pierce: Genetics - A Conceptual Approach 7th Edition (2020)

Conditions for acceptance of the semester

75% attendance to lectures and 85% to seminars and practices

Mid-term exams

One midterm test, that can be repeated two more times if necessary.

Making up for missed classes

None

Exam topics/questions

Teams, Neptun, Departmental website

Examiners

Instructor / tutor of practices and seminars

  • Ádám Zoltán Mihály
  • Garai Kitti