New national laboratory to improve the methodology of the treatment of neurological diseases

25 August 2022

In 2022, the University of Pécs, as consortium leader, and six consortium partners (ELKH Institute of Experimental Medicine, University of Szeged, Semmelweis University, ELKH Research Centre for Natural Sciences, ELKH Institute for Computer Science and Control, Richter Gedeon Nyrt.) has won HUF 5.300 billion in non-reimbursable EU funding under the call for proposals called "Establishment and complex development of national laboratories". The project, entitled "Translational Neuroscience National Laboratory", is being implemented in the frame of the Széchenyi Plan Plus and focuses on two main areas: neurodevelopmental disorders and nervous system disorders in adults.

The project aims to improve methodologies for the prevention and treatment of neurological diseases, with a unique research spectrum covering neurological disorders and diseases from childhood to adulthood. It aims to develop a comprehensive understanding of the disease mechanisms underlying neurological disorders in early life, and thus develop new diagnostic and intervention options.

Neurodevelopmental disorders are the result of a complex interaction of genetic and environmental factors. Neurodevelopmental disorders developing early in life are a lifelong burden for patients, their relatives, and society. It is now clear that from the emergence of the first neurons in the embryo to the development of the mature nervous system, the developing brain can be subject to a wide range of pathological effects that can lead to neurological diseases and mental disorders. Neurodevelopmental disorders include foetal alcohol syndrome, neonatal hypoxic brain injury, autism, and attention deficit hyperactivity disorder in childhood.

In the case of nervous system disorders in adults, the aim is to develop new treatments offering treatment alternatives, reducing the burden on the national economy. As digital medicine and data-driven healthcare are expanding, it is important to make direct use of real-life data in the therapy of neurological disorders by developing online platforms and registries. These are capable of online data uploading following the structure of existing neuroscience databases, preserving the searchability of existing databases, integrating health data from other institutions, are compatible with various clinical research programs and databases, and consider the utilization needs of the health insurance, health management, and healthcare industry.

The project will be implemented in the research sites and network of the consortium members. The professional leader of the project is Professor Tamás Dóczi.

Source:

PTE

Photo:

Szabolcs Csortos/UnivPécs