Introduction to Bioinformatics - Practice

Data

Official data in SubjectManager for the following academic year: 2025-2026

Topic

The course provides a general introduction to Bioinformatics. A survey of practical applications follows a brief theoretical overview for each sub-topic. Handling of genomic and structural data and the corresponding file types are introduced. A special emphasis is placed on structure-based drug design methodologies. Basic skills are practiced for each topic in the computer lab. The course is mostly based on open-source or free software, and the students are encouraged by homework to improve their computer skills further on their personal computers. Journal Club sessions supply additional up-to-date research results in bioinformatics and contribute to improving the presentation skills of the students.

Lectures

Practices

• 1. The bioinformatics toolkit - Hetényi Csaba
• 2. The bioinformatics toolkit - Hetényi Csaba
• 3. Databases - Börzsei Rita Judit
• 4. Databases - Börzsei Rita Judit
• 5.

  The decoding of prokaryotic and eukaryotic genomes

  - Rauch Tibor Attila, Deák Péter (Biokémia)
• 6.

  The decoding of prokaryotic and eukaryotic genomes

  - Rauch Tibor Attila, Deák Péter (Biokémia)
• 7.

  The functional analysis of genomes and epigenomes

  - Rauch Tibor Attila, Deák Péter (Biokémia)
• 8.

  The functional analysis of genomes and epigenomes

  - Rauch Tibor Attila, Deák Péter (Biokémia)
• 9.

  Comparative genome (DNA and RNA) analyses

  - Rauch Tibor Attila, Deák Péter (Biokémia)
• 10.

  Comparative genome (DNA and RNA) analyses

  - Rauch Tibor Attila, Deák Péter (Biokémia)
• 11. Molecular structure and visualization - Hetényi Csaba, Börzsei Rita Judit
• 12. Molecular structure and visualization - Hetényi Csaba, Börzsei Rita Judit
• 13. Structural measurements and manipulations - Börzsei Rita Judit
• 14. Structural measurements and manipulations - Börzsei Rita Judit
• 15. Building of ligands (drugs) - Hetényi Csaba, Börzsei Rita Judit
• 16. Building of ligands (drugs) - Hetényi Csaba, Börzsei Rita Judit
• 17. Building of targets (proteins) - Biskup Dóra
• 18. Building of targets (proteins) - Biskup Dóra
• 19. Molecular docking - Hetényi Csaba, Börzsei Rita Judit
• 20. Molecular docking - Hetényi Csaba, Börzsei Rita Judit
• 21. Structure-based drug design and molecular dynamics - Hetényi Csaba, Börzsei Rita Judit
• 22. Structure-based drug design and molecular dynamics - Hetényi Csaba, Börzsei Rita Judit
• 23. Descriptive and basic statistics - Hetényi Csaba
• 24. Descriptive and basic statistics - Hetényi Csaba
• 25. Pharmacoinformatics - Zsidó Balázs Zoltán
• 26. Pharmacoinformatics - Zsidó Balázs Zoltán
• 27. Journal club, test - Hetényi Csaba, Börzsei Rita Judit
• 28. Journal club, test - Hetényi Csaba, Börzsei Rita Judit

Seminars

Reading material

Obligatory literature

Literature developed by the Department

The material of the course including PDFs of practice handouts will be made downloadable from the website of the Department of Pharmacology and Pharmacotherapy or from TEAMS or a link will be provided during the lectures / in an e-mail.

Notes

Recommended literature

Paul M. Selzer, Richard J. Marhöfer, Oliver Koch
Applied Bioinformatics

Conditions for acceptance of the semester

- Homework accomplished
- Test writing OR test work accomplished

Mid-term exams

- Homework
- Test writing OR test work

Making up for missed classes

Replacement is not possible.

Exam topics/questions

Not applicable.

Examiners

• Biskup Dóra
• Börzsei Rita Judit
• Hetényi Csaba
• Rauch Tibor Attila
• Zsidó Balázs Zoltán

Instructor / tutor of practices and seminars

• Biskup Dóra
• Börzsei Rita Judit
• Deák Péter (Biokémia)
• Hetényi Csaba
• Rauch Tibor Attila
• Zsidó Balázs Zoltán