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Education

Introduction to Bioinformatics - Theory

Data

Official data in SubjectManager for the following academic year: 2026-2027

Course director

  • Hetényi Csaba

    associate professor,
    Department of Pharmacology and Pharmacotherapy

Number of hours/semester

lectures: 14 hours

practices: 0 hours

seminars: 0 hours

total of: 14 hours

Subject data

  • Code of subject: OBA-136_25-E
  • 1 kredit
  • Biotechnology MSc
  • Basic modul
  • spring semester
Prerequisites:

-

Course headcount limitations

min. 1 – max. 999

Available as Campus course for . Campus-karok: ÁOK GYTK TTK

Topic

The course provides a general introduction to Bioinformatics. A survey of practical applications follows a brief theoretical overview for each sub-topic. The handling of omics and structural data, along with the corresponding file types, is introduced. A special emphasis is placed on structure-based drug design methodologies. Basic skills are practiced in the computer lab for each topic. The course is mostly based on open-source or free software, and students are encouraged to further improve their computer skills through homework on their personal computers.

Lectures

  • 1. The bioinformatics toolkit 1 (Hardware, Software, Data types and streams) - Hetényi Csaba
  • 2. The bioinformatics toolkit 2 (Programming, Python, AI 1) - Hetényi Csaba
  • 3. Databases - Börzsei Rita Judit
  • 4. Sequence alignments and comparisons - Hetényi Csaba
  • 5. Molecular representations - Hetényi Csaba
  • 6. Structural measurements and manipulations - Hetényi Csaba
  • 7. Building of biomolecular targets - Hetényi Csaba
  • 8. Building of ligands - Hetényi Csaba
  • 9. Rational drug design 1 - Hetényi Csaba
  • 10. Rational drug design 2 - Hetényi Csaba
  • 11. Omics analyses - Hetényi Csaba
  • 12. The bioinformatics toolkit 3 (Probability and statistics, AI 2) - Hetényi Csaba
  • 13. Pharmacoinformatics - Zsidó Balázs Zoltán
  • 14. Discussion of problematic topics - Hetényi Csaba

Practices

Seminars

Reading material

Obligatory literature

Literature developed by the Department

The material of the course including pdfs of lectures and lists of key topics will be made downloadable from the website of the Department of Pharmacology and Pharmacotherapy or from TEAMS or a link will be provided during the lectures / in an e-mail.

Notes

Recommended literature

Paul M. Selzer, Richard J. Marhöfer, Oliver Koch
Applied Bioinformatics

Conditions for acceptance of the semester

- Test writing accomplished

Mid-term exams

The final test will be announced at the end of the semester. The test will include multiple-choice questions and/or short essays. A mark is awarded based on the results of the written test. The student can improve the mark according to university regulations.

Making up for missed classes

Replacement is not possible.

Exam topics/questions

Lists of key topics will be provided for each lecture in PDF format.

Examiners

  • Börzsei Rita Judit
  • Hetényi Csaba
  • Zsidó Balázs Zoltán

Instructor / tutor of practices and seminars

  • Börzsei Rita Judit
  • Hetényi Csaba
  • Zsidó Balázs Zoltán
Rólunk