Pharmacology for Dentistry Students 1

Data

Official data in SubjectManager for the following academic year: 2023-2024

Topic

The general aim of the subject is to provide the dentistry students with all the basic information in pharmacology necessary to understand the actions of drugs and the clinical pharmacotherapy. Pharmacology can be defined as the study of the manner in which the function of living systems is affected by chemical agents. Therefore, the students should be familiar with the basic knowledge of the physiological, pathophysiological and biochemical background of the pharmacological and therapeutic approaches. On the other hand, drug therapy is closely related to the clinical aspects of diseases.
The following topics will be dealt with. Definitions, prescription writing, drug development, drug formulations. General aspects of mechanisms of drug actions: characterization of drug-receptor interactions, mechanisms of drug antagonism, signal transduction mechanisms of drug receptors. General and quantitative aspects of pharmacokinetics: absorption, distribution and elimination of drugs. Pharmacology of the autonomic nervous system. Local anaesthetics.
Cardiovascular pharmacology: drugs used to treat congestive heart failure, antianginal, antiarrhythmic, antihypertensive drugs, diuretics, calcium channel blockers, drugs acting on the renin-angiotensin-aldosterone system. Drugs affecting haemostasis, haematopoesis and hyperlipoproteinaemias. Pharmacology of histamine, serotonin.

Lectures

• 1. Introduction to pharmacology, drug development - Dr. Sándor Zoltán
• 2. Basic mechanisms of drug effects - Dr. Sándor Zoltán
• 3. Signal transduction - Dr. Sándor Zoltán
• 4. Characteristics of the agonist-receptor interaction I. - Dr. Csekő Kata
• 5. Characteristics of the agonist-receptor interaction II. - Dr. Csekő Kata
• 6. Antagonism, tachyphylaxis and tolerance - Dr. Csekő Kata
• 7. Absorption, distribution, biotransformation and excretion - Dr. Gasznerné Dr. Kormos Viktória
• 8. Quantitative pharmacokinetics I. - Dr. Gasznerné Dr. Kormos Viktória
• 9. Quantitative pharmacokinetics II. - Dr. Gasznerné Dr. Kormos Viktória
• 10. Introduction to the pharmacology of the autonomic nervous system - Dr. Csekő Kata
• 11. Cholinerg agonists, cholinesterase inhibitors - Dr. Csekő Kata
• 12. Muscarine receptor antagonists - Dr. Csekő Kata
• 13. Drugs acting on the synthesis, storage, release and elimination of catecholamines - Dr. Gasznerné Dr. Kormos Viktória
• 14. Adrenergic receptor agonists - Dr. Gasznerné Dr. Kormos Viktória
• 15. Adrenergic receptor antagonists - Dr. Gasznerné Dr. Kormos Viktória
• 16. Local anaesthetics I. - Dr. Csekő Kata
• 17. Local anaesthetics II. - Dr. Csekő Kata
• 18. Calcium channel blockers - Dr. Csekő Kata
• 19. Drugs acting on the renin-angiotensin system - Dr. Sándor Zoltán
• 20. Diuretics - Dr. Sándor Zoltán
• 21. Therapy of congestive heart failure - Dr. Sándor Zoltán
• 22. Antianginal drugs - Dr. Csekő Kata
• 23. Pharmacotherapy of hypertension - Dr. Csekő Kata
• 24. Antiarrhythmic drugs - Dr. Csekő Kata
• 25. Eicosanoids - Dr. Gasznerné Dr. Kormos Viktória
• 26. Drugs acting on smooth muscle - Dr. Gasznerné Dr. Kormos Viktória
• 27. Pharmacotherapy of hyperlipoproteinemias - Dr. Gasznerné Dr. Kormos Viktória
• 28. Drugs influencing haemostasis I. - Dr. Csekő Kata
• 29. Drugs influencing haemostasis II. - Dr. Csekő Kata
• 30. Drugs influencing haemostasis III. - Dr. Csekő Kata
• 31. Drugs influencing haematopoiesis - Dr. Gasznerné Dr. Kormos Viktória
• 32. Drugs acting on the respiratory system I. - Dr. Gasznerné Dr. Kormos Viktória
• 33. Drugs acting on the respiratory system II. - Dr. Gasznerné Dr. Kormos Viktória
• 34. Peripheral muscle relaxants - Dr. Sándor Zoltán
• 35. Histamine and histamine receptor antagonists - Dr. Sándor Zoltán
• 36. Serotonin and 5-HT receptor agonists and antagonists - Dr. Sándor Zoltán
• 37. Drug formulations I. - Dr. Sándor Zoltán
• 38. Drug formulations II. - Dr. Sándor Zoltán
• 39. Drug formulations III. - Dr. Sándor Zoltán
• 40. Consultation I. - Dr. Sándor Zoltán
• 41. Consultation II. - Dr. Sándor Zoltán
• 42. Test writing - Dr. Sándor Zoltán

Practices

Seminars

Reading material

Obligatory literature

Rang, Dale,B. Ritter, Moore: Pharmacology, 8th edition, Elsevier Churchill Livingstone, 2015.
G. Katzung (ed.): Basic and Clinical Pharmacology, 12th edition, Lange Medical Books/McGraw-Hill, 2012.

Literature developed by the Department

Intranet. Department of Pharmacology and Pharmacotherapy. Educational materials.
Neptun Meet Street

Notes

Recommended literature

Conditions for acceptance of the semester

For the semester to be accepted students are allowed to be absent from maximum 9 lectures.

Mid-term exams

There is no mid-term examination.

Making up for missed classes

Not possible

Exam topics/questions

1. Introduction to pharmacology , drug development
2. Basic mechanisms of drug effects
3. Signal transduction
4. Characteristics of the agonist-receptor interaction I.
5. Characteristics of the agonist-receptor interaction II.
6. Antagonism, tachyphylaxis and tolerance
7. Absorption, distribution, biotransformation and excretion
8. Quantitative pharmacokinetics I.
9. Quantitative pharmacokinetics II.
10. Introduction to the pharmacology of the autonomic nervous system
11. Cholinerg agonists, cholinesterase inhibitors
12. Muscarine receptor antagonists
13. Drugs acting on the synthesis, storage, release and elimination of catecholamines
14. Adrenergic receptor agonists
15. Adrenergic receptor antagonists
16. Local anaesthetics I.
17. Local anaesthetics II.
18. Calcium channel blockers
19. Drugs acting on the renin-angiotensin system
20. Diuretics
21. Therapy of congestive heart failure
22. Antianginal drugs
23. Pharmacotherapy of hypertension
24. Antiarrhythmic drugs
25. Eicosanoids
26. Drugs acting on smooth muscle
27. Pharmacotherapy of hyperlipoproteinemias
28. Drugs influencing haemostasis I.
29. Drugs influencing haemostasis II.
30. Drugs influencing haemostasis III.
31. Drugs influencing haematopoiesis
32. Drugs acting on the respiratory system I
33. Drugs acting on the respiratory system II
34. Peripheral muscle relaxants
35. Histamine and histamine receptor antagonists
36. Serotonin and 5-HT agonists and antagonists
37. Drug formulations I
38. Drug formulations II
39. Drug formulations III
40. Consultation I
41. Consultation II
42. Test writing

The condition for passing the exam is at least satisfactory completion of the written test based on the listed topics.

Examiners

• Dr. Sándor Zoltán
• Dr. Sánticsné Dr. Pintér Erika
• Dr. Tamasikné Dr. Helyes Zsuzsanna

Instructor / tutor of practices and seminars

• Dr. Csekő Kata
• Dr. Gasznerné Dr. Kormos Viktória
• Dr. Sándor Zoltán