Pharmacology for Dentistry Students 2

Data

Official data in SubjectManager for the following academic year: 2023-2024

Topic

The general aim of the subject is to provide the dentistry students with all the basic information in pharmacology necessary to understand the actions of drugs and the clinical pharmacotherapy. Pharmacology can be defined as the study of the manner in which the function of living systems is affected by chemical agents. Therefore, the students should be familiar with the basic knowledge of the physiological, pathophysiological and biochemical background of the pharmacological and therapeutic approaches. On the other hand, drug therapy is closely related to the clinical aspects of diseases.
The following topics will be dealt with. Opioid analgesic drugs, cyclooxygenase inhibitors. Pharmacology of the central nervous system: general anaesthetics, antipsychotic drugs, antidepressants, antianxiety and hypnotic drugs, antiepileptics, treatment of neurodegenerative disorders, drug abuse and dependence. Pharmacology of the respiratory and the gastrointestinal tract. Pharmacology of the endocrine system: pituitary hormones, corticosteroids, reproductive system, thyroid hormones, antithyroid drugs, insulin, glucagon and oral hypoglycemic agents, vitamin D, treatment of osteoporosis. Chemotherapy: sulphonamides and trimethoprim, fluoroquinolones, beta-lactam antibiotics, aminoglycosides, antituberculotics. Antifungal drugs, antiviral agents, antiseptics and disinfectants.

Lectures

• 1. Anxiolytic and hypnotic drugs - Dr. Csekő Kata
• 2. Antidepressants - Dr. Csekő Kata
• 3. Antipsychotics - Dr. Sándor Zoltán
• 4. Antiepileptics - Dr. Sándor Zoltán
• 5. General anaesthetics I - Dr. Csekő Kata
• 6. General anaesthetics II - Dr. Csekő Kata
• 7. Opioid analgesics I - Dr. Csekő Kata
• 8. Opioid analgesics II - Dr. Csekő Kata
• 9. NSAIDs I. - Dr. Gasznerné Dr. Kormos Viktória
• 10. NSAIDs II. Pharmacotherapy of gout - Dr. Gasznerné Dr. Kormos Viktória
• 11. Pharmacotherapy of peptic ulcer - Dr. Gasznerné Dr. Kormos Viktória
• 12. Emetics, anti-emetics, prokinetic drugs - Dr. Gasznerné Dr. Kormos Viktória
• 13. Laxatives, antidiarrhoeal drugs. Choleretic and cholekinetic drugs. - Dr. Gasznerné Dr. Kormos Viktória
• 14. Drugs protecting the liver. Therapy of inflammatory bowel disease - Dr. Gasznerné Dr. Kormos Viktória
• 15. Introduction to antimicrobial pharmacotherapy - Dr. Csekő Kata
• 16. Sulfonamides, trimethoprim. Fluoroquinolones - Dr. Csekő Kata
• 17. Beta lactam antibiotics I. - Dr. Csekő Kata
• 18. Beta lactam antibiotics II. Glycopeptide antibiotics - Dr. Csekő Kata
• 19. Tetracyclines, chloramphenicol, linezolid, clindamycin, metronidazole - Dr. Csekő Kata
• 20. Aminoglycosides. Macrolides - Dr. Csekő Kata
• 21. Antiviral drugs I. - Dr. Gasznerné Dr. Kormos Viktória
• 22. Antiviral drugs II. - Dr. Gasznerné Dr. Kormos Viktória
• 23. Drug abuse I. - Dr. Gasznerné Dr. Kormos Viktória
• 24. Drug abuse II. - Dr. Gasznerné Dr. Kormos Viktória
• 25. Pharmacotherapy of neurodegenerative disorders. - Dr. Sándor Zoltán
• 26. Centrally acting muscle relaxants. Disinfectants, antiseptics - Dr. Sándor Zoltán
• 27. Cytotoxic and embryotoxic adverse effects of drugs - Dr. Sándor Zoltán
• 28. Drug allergy. Drug interactions - Dr. Sándor Zoltán

Practices

Seminars

Reading material

Obligatory literature

Rang, Dale, Ritter, Moore: Pharmacology, 8th edition, Elsevier Churchill Livingstone, 2015.
B. G. Katzung (ed.): Basic and Clinical Pharmacology, 12th edition, Lange Medical Books/McGraw-Hill, 2012.

Literature developed by the Department

Intranet. Department of Pharmacology and Pharmacotherapy. Educational materials.
Neptun Meet Street

Notes

Recommended literature

Conditions for acceptance of the semester

For the semester to be accepted students should be absent from no more than 6 lectures.

Mid-term exams

There is no mid/term examination.

Making up for missed classes

Not possible

Exam topics/questions

1. Drug development
2. Basic mechanisms of drug effects
3. Characteristics of the agonist-receptor interaction
4. Signal transduction
5. Tachyphylaxis and tolerance. Antagonism
6. Absorption
7. Distribution
8. Biotransformation
9. Excretion
10. Quantitative pharmacokinetics
11. Cholinergic agonists. Cholinesterase inhibitors
12. Muscarine receptor antagonists
13. Peripheral muscle relaxants
14. Drugs acting on the synthesis, storage, release and elimination of catecholamines
15. Adrenergic receptor agonists
16. Adrenergic receptor antagonists
17. Histamine and histamine receptor antagonists
18. Serotonin, 5-HT receptor agonists and antagonists
19. Eicosanoids
20. Drugs influencing smooth muscles
21. Local anaesthetics
22. Calcium channel blockers
23. Drugs acting on the renin-angiotensin-aldosterone system
24. Diuretics
25. Pharmacotherapy of congestive heart failure
26. Antianginal drugs
27. Pharmacotherapy of hypertension
28. Anti-arrhythmic drugs
29. Pharmacotherapy of hyperlipoproteinemias
30. Drugs influencing haemostasis
31. Drugs influencing haematopoiesis
32. Drugs acting on the respiratory system: pharmacotherapy of bronchial asthma
33. Drugs acting on the respiratory system: Pharmacotherapy of allergic rhinitis. Antitussive, expectorant and mucolytic drugs
34. General anaesthetics
35. Anxiolytic and hypnotic drugs
36. Antipsychotics
37. Antidepressants
38. Antiepileptic drugs. Centrally acting muscle relaxants
39. Pharmacotherapy of neurodegenerative disorders
40. Opioid analgesics: morphine and codeine
41. Opioid analgesics: semisynthetic, synthetic drugs and antagonists
42. NSAIDs: aspirin and paracetamol. Pharmacotherapy of gout
43. NSAIDs except aspirin and paracetamol
44. Pharmacotherapy of peptic ulcer
45. Emetics, anti-emetics, prokinetic drugs
46. Laxatives, antidiarrhoeal drugs. Choleretic and cholekinetic drugs. Drugs protecting the liver. Pharmacotherapy of inflammatory bowel disease
47. Sulfonamides, trimethoprim. Fluoroquinolones
48. Beta-lactam antibiotics. Glycopeptide antibiotics
49. Tetracyclines, chloramphenicol, linezolid, clindamycin, metronidazole
50. Aminoglycosides. Macrolides
51. Antiviral drugs
52. Antiseptics and disinfectants
53. Drug abuse: General aspects. Opioids, central nervous system depressants
54. Drug abuse: psychomotor stimulants, hallucinogens, cannabis
55. Cytotoxic and embryotoxic adverse effects of drugs. Drug allergy
56. Drug interactions
57. Hypothalamic and pituitary hormones
58. Thyroid hormones and antithyroid drugs
59. Corticosteroids
60. Estrogens, anti-estrogens, progestogens, antiprogestogens
61. Postmenopausal hormone replacement therapy. Hormonal contraceptives
62. Androgens, anabolic steroids and anti-androgens
63. Parathormone, calcitonin, vitamin D and pharmacotherapy of osteoporosis
64. Insulin, insulin analogues. Oral antidiabetic drugs. Glucagon
65. Anticancer drugs: alkylating agents, antimetabolites
66. Anticancer drugs: antibiotics, alkaloids, hormones, biological therapy
67. Immunosuppressants. Immunomodulators. Pharmacotherapy of rheumatoid arthritis
68. Antituberculotics
69. Antifungal drugs

Examiners

• Dr. Sándor Zoltán
• Dr. Sánticsné Dr. Pintér Erika
• Dr. Tamasikné Dr. Helyes Zsuzsanna

Instructor / tutor of practices and seminars

• Dr. Csekő Kata
• Dr. Gasznerné Dr. Kormos Viktória
• Dr. Sándor Zoltán