Pharmacology for Dentistry Students 2

Data

Official data in SubjectManager for the following academic year: 2024-2025

Topic

The general aim of the subject is to provide the dentistry students with all the basic information in pharmacology necessary to understand the actions of drugs and the clinical pharmacotherapy. Pharmacology can be defined as the study of the manner in which the function of living systems is affected by chemical agents. Therefore, the students should be familiar with the basic knowledge of the physiological, pathophysiological and biochemical background of the pharmacological and therapeutic approaches. On the other hand, drug therapy is closely related to the clinical aspects of diseases.

The following topics will be dealt with. Opioid analgesic drugs, cyclooxygenase inhibitors. Pharmacology of the central nervous system: general anaesthetics, antipsychotic drugs, antidepressants, antianxiety and hypnotic drugs, antiepileptics, treatment of neurodegenerative disorders, drug abuse and dependence. Pharmacology of the respiratory and the gastrointestinal tract. Pharmacology of the endocrine system: pituitary hormones, corticosteroids, reproductive system, thyroid hormones, antithyroid drugs, insulin, glucagon and oral hypoglycemic agents, vitamin D, treatment of osteoporosis. Chemotherapy: sulphonamides and trimethoprim, fluoroquinolones, beta-lactam antibiotics, aminoglycosides, antituberculotics. Antifungal drugs, antiviral agents, antiseptics and disinfectants.

Lectures

• 1.

  Anxiolytic and hypnotic drugs

  - Al-Omari Ammar Abdallah Khalaf
• 2.

  Antidepressants

  - Al-Omari Ammar Abdallah Khalaf
• 3. Antipsychotics - Sándor Zoltán (1968, Farmakológia)
• 4. Antiepileptics - Sándor Zoltán (1968, Farmakológia)
• 5.

  General anaesthetics I

  - Al-Omari Ammar Abdallah Khalaf
• 6.

  General anaesthetics II

  - Al-Omari Ammar Abdallah Khalaf
• 7.

  Opioid analgesics I

  - Al-Omari Ammar Abdallah Khalaf
• 8.

  Opioid analgesics II

  - Al-Omari Ammar Abdallah Khalaf
• 9. NSAIDs I. - Gasznerné Kormos Viktória
• 10. NSAIDs II. Pharmacotherapy of gout - Gasznerné Kormos Viktória
• 11. Pharmacotherapy of peptic ulcer - Gasznerné Kormos Viktória
• 12. Emetics, anti-emetics, prokinetic drugs - Gasznerné Kormos Viktória
• 13. Laxatives, antidiarrhoeal drugs. Choleretic and cholekinetic drugs. - Gasznerné Kormos Viktória
• 14. Drugs protecting the liver. Therapy of inflammatory bowel disease - Gasznerné Kormos Viktória
• 15.

  Introduction to antimicrobial pharmacotherapy

  - Sándor Zoltán (1968, Farmakológia)
• 16.

  Sulfonamides, trimethoprim. Fluoroquinolones

  - Sándor Zoltán (1968, Farmakológia)
• 17.

  Beta lactam antibiotics I.

  - Al-Omari Ammar Abdallah Khalaf
• 18.

  Beta lactam antibiotics II. Glycopeptide antibiotics

  - Al-Omari Ammar Abdallah Khalaf
• 19.

  Tetracyclines, chloramphenicol, linezolid, clindamycin, metronidazole

  - Al-Omari Ammar Abdallah Khalaf
• 20.

  Aminoglycosides. Macrolides

  - Al-Omari Ammar Abdallah Khalaf
• 21. Antiviral drugs I. - Gasznerné Kormos Viktória
• 22. Antiviral drugs II. - Gasznerné Kormos Viktória
• 23. Drug abuse I. - Gasznerné Kormos Viktória
• 24. Drug abuse II. - Gasznerné Kormos Viktória
• 25. Pharmacotherapy of neurodegenerative disorders. - Sándor Zoltán (1968, Farmakológia)
• 26. Centrally acting muscle relaxants. Disinfectants, antiseptics - Sándor Zoltán (1968, Farmakológia)
• 27. Cytotoxic and embryotoxic adverse effects of drugs - Sándor Zoltán (1968, Farmakológia)
• 28. Drug allergy. Drug interactions - Sándor Zoltán (1968, Farmakológia)

Practices

Seminars

Reading material

Obligatory literature

Rang, Dale, Ritter, Moore: Pharmacology, 8th edition, Elsevier Churchill Livingstone, 2015.

B. G. Katzung (ed.): Basic and Clinical Pharmacology, 12th edition, Lange Medical Books/McGraw-Hill, 2012.

Literature developed by the Department

Intranet. Department of Pharmacology and Pharmacotherapy. Educational materials.

Neptun Meet Street

Notes

Recommended literature

Conditions for acceptance of the semester

For the semester to be accepted students should be absent from no more than 6 lectures.

Mid-term exams

There is no mid/term examination.

Making up for missed classes

Not possible

Exam topics/questions

1. Drug development

2. Basic mechanisms of drug actions, signaling processes

3. Characterization of the agonist-receptor interaction

4. Antagonism, tachyphylaxis and tolerance

5. Absorption, distribution,

6. Biotransformation and secretion

7. Pharmacokinetic parameters

8. Cholinergic agonists, cholinesterase inhibitors

9. Muscarinic receptor antagonists

10. Drugs affecting the synthesis, release and elimination of catecholamines

11. Adrenergic receptor agonists

12. Adrenergic receptor antagonists

13. Local anesthetics

14. Calcium channel blockers

15. Agents acting on the renin-angiotensin-aldosterone system

16. Diuretics

17. Treatment of congestive heart failure

18. Antianginal drugs

19. Treatment of high blood pressure

20. Antiarrhythmic drugs

21. Eicosanoids and smooth muscle agents

22. Agents acting on hyperlipoproteinemias

23. Anticoagulants, antiplatelet agents

24. Fibrinolytics, antifibrinolytics, hemostatic agents

25. Agents affecting hematopoiesis

26. Agents affecting the respiratory system

27. Peripheral muscle relaxants

28. Histamine and histamine receptor antagonists

29. Serotonin, 5-HT-receptor agonists and antagonists, migraine therapy

30. Basics of fluid therapy

31. Non-steroidal anti-inflammatory drugs, drugs used to treat gout

32. Antitumor drugs

33. Immunosuppressants, immunomodulators. Treatment of rheumatoid arthritis

34. Agents used to treat peptic ulcer

35. Emetics and antiemetics. Agents affecting liver and gallbladder function.

36. Laxatives and obstipants. Medicines for inflammatory bowel diseases

37. Anxiolytics, hypnotics

38. Antipsychotics

39. Antidepressants

40. Antiepileptic drugs

41. General anesthetics

42. Medicines for neurodegenerative diseases

43. Opioid analgesics

44. Adjuvant analgesics. Central muscle relaxants

45. Hormones of the hypothalamus and pituitary gland

46. ​​Corticosteroids

47. Sex hormones, contraception, post-menopausal hormone therapy

48. Thyroid hormones, antithyroid drugs

49. Insulin, oral antidiabetics. Glucagon

50. Parathormone, calcitonin and vitamin D, drug treatment of osteoporosis

51. Sulfonamides, trimethoprim, pyrimethamine. Fluoroquinolones

52. Nitroimidazoles. RNA polymerase inhibitors

53. Beta lactam antibiotics

54. Glycopeptide antibiotics, daptomycin, fosfomycin, bacitracin, polymyxins, gramicidins

55. Tetracyclines, aminoglycosides

56. Macrolide antibiotics, clindamycin, chloramphenicol, oxazolidinones, streptogramins

57. Antituberculotics, antifungals, anthelmintics

58. Antiviral agents, disinfectants

59. Factors influencing drug effects, drug interactions

60. Poisoning caused by medicines, drug abuse

Examiners

• Gasznerné Kormos Viktória
• Sándor Zoltán (1968, Farmakológia)

Instructor / tutor of practices and seminars

• Al-Omari Ammar Abdallah Khalaf
• Gasznerné Kormos Viktória
• Sándor Zoltán (1968, Farmakológia)