Pharmacology 2

Data

Official data in SubjectManager for the following academic year: 2024-2025

Topic

The general aim of the subject is to provide the medical students with all the basic information in pharmacology necessary to understand the actions of drugs and the clinical pharmacotherapy and to pass the Foreign Medical Graduate Examination in Medical Sciences. Pharmacology can be defined as the study of the manner in which the function of living systems is affected by chemical agents. Therefore, the students should be familiar with the basic knowledge of the physiological, pathophysiological and biochemical background of the pharmacological and therapeutic approaches. On the other hand, drug therapy is closely related to the clinical aspects of diseases.

The following topics will be dealt with: Cardiovascular pharmacology: drugs used to treat congestive heart failure, antianginal, antiarrhythmic, antihypertensive drugs, diuretics, calcium channel blockers, drugs acting on the renin-angiotensin-aldosterone system. Drugs affecting haemostasis, haematopoiesis and hyperlipoproteinaemias. Opioid analgesic drugs, cyclooxygenase inhibitors. Pharmacology of the central nervous system: general anaesthetics, alcohols, antipsychotic drugs, antidepressants, antianxiety and hypnotic drugs, antiepileptics, central nervous system stimulants, nootropic agents, treatment of neurodegenerative disorders, drug abuse and dependence. Pharmacology of the gastrointestinal tract. Drugs used to treat cancer, immunopharmacology.

Lectures

• 1. Calcium channel blockers - Tamasikné Helyes Zsuzsanna
• 2. Drugs acting on the renin-angiotensin-aldosterone system - Sánticsné Pintér Erika
• 3. Diuretic drugs I - !Gregus Zoltán (elhunyt)
• 4. Diuretic drugs II - !Gregus Zoltán (elhunyt)
• 5. Drugs used to treat congestive heart failure - Tamasikné Helyes Zsuzsanna
• 6. Antianginal drugs - Pethő Gábor István
• 7. Antiarrhythmic drugs I - Pethő Gábor István
• 8. Antiarrhythmic drugs II - Pethő Gábor István
• 9. Antihypertensive drugs - Sánticsné Pintér Erika
• 10. Drugs used to treat obesity - Sánticsné Pintér Erika
• 11. Drugs used to treat cancer I - Pethő Gábor István
• 12. Drugs used to treat cancer II - Pethő Gábor István
• 13. Immunosuppressants I - Sánticsné Pintér Erika
• 14. Immunosuppressants II - Sánticsné Pintér Erika
• 15. Immunomodulators. Drugs used to treat rheumatoid arthritis - Sánticsné Pintér Erika
• 16. Neurotransmitters of the central nervous system. Basics of drug abuse - Sánticsné Pintér Erika
• 17. Antianxiety and hypnotic drugs I - Barthó Loránd
• 18. Antianxiety and hypnotic drugs II - Barthó Loránd
• 19. Antipsychotic drugs I - Borbély Éva
• 20. Antipsychotic drugs II - Borbély Éva
• 21. Antidepressants I - Sánticsné Pintér Erika
• 22. Antidepressants II - Sánticsné Pintér Erika
• 23. Antiepileptic drugs - Pethő Gábor István
• 24. Pharmacological aspects of serotonin - Pethő Gábor István
• 25. Opioid analgesic drugs I - Pethő Gábor István
• 26. Opioid analgesic drugs II - Pethő Gábor István
• 27. Non-steroidal antiinflammatory drugs I - Pethő Gábor István
• 28. Non-steroidal antiinflammatory drugs II - Pethő Gábor István

Practices

Seminars

• 1. Drugs used to treat hyperlipoproteinemias I
• 2. Drugs used to treat hyperlipoproteinemias II
• 3. Drugs affecting hematopoiesis I
• 4. Drugs affecting hematopoiesis II
• 5. Drugs affecting hemostasis I
• 6. Drugs affecting hemostasis II
• 7. Drugs affecting hemostasis III
• 8. Pharmacology of the gastrointestinal tract I
• 9. Pharmacology of the gastrointestinal tract II
• 10. Pharmacology of the gastrointestinal tract III
• 11. Pharmacology of the gastrointestinal tract IV
• 12. Pharmacology of the gastrointestinal tract V
• 13. Drugs increasing regional blood flow
• 14. Discussion of cardiovascular drugs
• 15. General anesthetics I
• 16. General anesthetics II
• 17. Pharmacology of alcohols I
• 18. Pharmacology of alcohols II
• 19. Drug treatment of neurodegenerative disorders I
• 20. Drug treatment of neurodegenerative disorders II
• 21. Psychomotor stimulants. Nootropic drugs
• 22. Adjuvant analgesics. Centrally-acting skeletal muscle relaxants. Drug treatment of gout
• 23. Drug abuse and dependence: general principles
• 24. Drug abuse and dependence: opioids, antianxiety and hypnotic drugs, alcohol
• 25. Drug abuse and dependence: psychomotor stimulants, nicotine, inhalants
• 26. Drug abuse and dependence: psychedelics, cannabis
• 27. Discussion of drugs acting on the CNS I
• 28. Discussion of drugs acting on the CNS II

Reading material

Obligatory literature

Literature developed by the Department

Materials related to the topics discussed in lectures and seminars will be available in Neptun.

Notes

Recommended literature

Rang, Dale, Ritter, Moore: Pharmacology, 9th edition, Elsevier Churchill Livingstone, 2020

B. G. Katzung (ed.): Basic and Clinical Pharmacology, 14th edition, Lange Medical Books/McGraw-Hill, 2018

Conditions for acceptance of the semester

-

Mid-term exams

There is no mid-semester test.

Making up for missed classes

Each missed seminar has to be made up for with another group in the same week.

Exam topics/questions

1. Calcium channel blockers

2. Drugs acting on the renin-angiotensin-aldosterone system

3. Diuretic drugs

4. Antiarrhythmic drugs

5. Drugs used to treat congestive heart failure

6. Antianginal drugs

7. Antihypertensive drugs

8. Drugs that increase regional blood flow. Drug treatment of obesity

9. Drugs used to treat hyperlipoproteinemias

10. Anticoagulants, antiplatelet drugs

11. Fibrinolytics, antifibrinolytics, hemostatic agents

12. Drugs affecting hematopoiesis

13. Antineoplastic drugs: alkylating agents, antimetabolites, microtubule-damaging drugs, topoisomerase inhibitors

14. Antineoplastic drugs: cytokines, tyrosine kinase inhibitors, monoclonal antibodies, agents inducing differentiation

15. Immunosuppressants, immunomodulators, treatment of rheumatoid arthritis

16. Antianxiety and hypnotic drugs

17. Alcohols: pharmacology, toxicology

18. Antipsychotic drugs

19. Antidepressants

20. General anesthetics

21. Psychomotor stimulants and nootropic agents

22. Antiepileptic drugs

23. Drug treatment of neurodegenerative disorders

24. Drug abuse and dependence: general principles, opioids, anti-anxiety and hypnotic drugs, inhalants, ethanol

25. Drug abuse and dependence: psychomotor stimulants, psychedelics, cannabis

26. Opioid analgesic drugs: morphine and codeine

27. Opioid analgesic drugs: semisynthetic, synthetic opioids, opioid antagonists

28. Non-steroidal antiinflammatory drugs: aspirin, paracetamol

29. Non-steroidal antiinflammatory drugs: drugs other than aspirin or paracetamol

30. Adjuvant analgesics. Drugs used to treat gout. Centrally-acting muscle relaxants

31. Drugs used in the treatment of peptic ulcer

32. Emetics, antiemetics and prokinetic drugs

33. Laxatives, antidiarrhoeal agents, drug treatment of inflammatory bowel disease and paralytic ileus, digestives, drugs used in cholelithiasis

34. Serotonin, serotonin receptor agonists and antagonists

Upon the oral exam, 2 exam topics are chosen. In addition to these exam topics, important parts of the exam are the questions that aim at assessing the general knowledge of the student. Bad performance in this part of the exam may lead to failure regardless of the answers to exam topics.

Examiners

• Barthó Loránd
• Borbély Éva
• Pethő Gábor István
• Pozsgai Gábor
• Sánticsné Pintér Erika
• Tamasikné Helyes Zsuzsanna

Instructor / tutor of practices and seminars

• Börzsei Rita Judit
• Horváth Ádám (Farmakológia)
• Zsidó Balázs Zoltán