Medical Applications of Mass Spectrometry

Daten

Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2022-2023

Lehrbeauftragte/r

  • Dr. László MÁRK

    associate professor,
    Department of Biochemistry and Medical Chemistry

Semesterwochenstunden

Vorlesungen: 20

Praktika: 0

Seminare: 0

Insgesamt: 20

Fachangaben

  • Kode des Kurses: OTF-TSS-T
  • 2 kredit
  • Biotechnology BSc
  • Optional modul
  • autumn
Voraussetzungen:

keine

Zahl der Kursteilnehmer für den Kurs:

min. 3 – max. 50

Thematik

In medical sciences, emphasis is increasingly placed on instrumental techniques and accurate, quantitative measurements. This course is give an overall review about the modern mass spectrometry and it shows the medical applications of the MS in the clinical and diagnostic practice.
Topics:
Introduction to MS. Ionsources, analizators, detectors. Separation techniques. Sample handling. Biomedical sampling. Bioinformatics. Proteomics, metabolomics and lipidomics. Biomarker discovery. Mass spectrometric imaging techniques.

Vorlesungen

  • 1. Introduction to mass spectrometry - Dr. Márk László
  • 2. Introduction to mass spectrometry - Dr. Márk László
  • 3. Ionsources - Dr. Márk László
  • 4. Analyzers - Dr. Márk László
  • 5. The mass spectrum. - Dr. Márk László
  • 6. Sample matrices, Sampling procedures. - Dr. Márk László
  • 7. Sample pretreatment, separation techniques. - Dr. Márk László
  • 8. Sample pretreatment, separation techniques. - Dr. Márk László
  • 9. Proteomics - Dr. Márk László
  • 10. Proteomics - Dr. Márk László
  • 11. Metabolomics - Dr. Márk László
  • 12. Metabolomics - Dr. Márk László
  • 13. Investigation of endocrine system - Dr. Márk László
  • 14. Investigation of endocrine system - Dr. Márk László
  • 15. Pathological biomarker discovery - Dr. Márk László
  • 16. Pathological biomarker discovery - Dr. Márk László
  • 17. Lipidomics - Dr. Márk László
  • 18. Lipidomics - Dr. Márk László
  • 19. Imaging mass spectrometry - Dr. Márk László
  • 20. Imaging mass spectrometry - Dr. Márk László

Praktika

Seminare

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Vom Institut veröffentlichter Lehrstoff

Lecture slides and notes.

Skript

Empfohlene Literatur

Vékey et al: Medical Applications of Mass Spectrometry, 2008.
Hoffman et al: Mass Spectrometry, 2007

Voraussetzung zum Absolvieren des Semesters

Written exam. Max. absences: 20%.

Semesteranforderungen

Not possible.

Möglichkeiten zur Nachholung der Fehlzeiten

Not possible.

Prüfungsfragen

Ionsources.
Analizators.
Detectors.
Separation techniques.
Sample handling. Biomedical sampling.
Bioinformatics.
Proteomics.
Metabolomics
Lipidomics.
Biomarker discovery.
Mass spectrometric imaging techniques.
MS of endocrine system.

Prüfer

Praktika, Seminarleiter/innen