Molecular Toxicology - Lecture

Daten

Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2024-2025

Thematik

Molecular toxicology as a subject deals with the toxic (including teratogenic and carcinogenic) effects of drugs and xenobiotics caused by overdose or excessive exposure. It describes the general aspects of toxicology, the mechanisms of toxicity (including the major influencing factors), the harmful effects, and certain aspects of the treatment options. In addition, toxicity testing will be also discussed.

Vorlesungen

• 1.

  Introduction of toxicology.

  - Hartnerné Pohóczky Krisztina
• 2.

  The principles of toxicodynamics.

  - Hartnerné Pohóczky Krisztina
• 3.

  The principles of toxicokinetics I.

  - Hartnerné Pohóczky Krisztina
• 4.

  The principles of toxicokinetics II.

  - Hartnerné Pohóczky Krisztina
• 5.

  The principles of toxicokinetics III.

  - Hartnerné Pohóczky Krisztina
• 6.

  The principles of toxicokinetics IV.

  - Hartnerné Pohóczky Krisztina
• 7.

  Toxic effects caused by biological mimicri I.

  - Hartnerné Pohóczky Krisztina
• 8.

  Toxic effects caused by biological mimicri II.

  - Hartnerné Pohóczky Krisztina
• 9.

  Disruption of cellular energy production I.

  - Hartnerné Pohóczky Krisztina
• 10.

  Disruption of cellular energy production II.

  - Hartnerné Pohóczky Krisztina
• 11.

  Disruption of cell homeostasis and/or physiology I.

  - Hartnerné Pohóczky Krisztina
• 12.

  Disruption of cell homeostasis and/or physiology II.

  - Hartnerné Pohóczky Krisztina
• 13.

  Summary and consultation I.

  - Hartnerné Pohóczky Krisztina
• 14.

  Summary and consultation II.

  - Hartnerné Pohóczky Krisztina
• 15.

  Xenobiotics causing tissue injury or tissue necrosis

  - Hartnerné Pohóczky Krisztina
• 16.

  Xenobiotics causing CNS toxicity

  - Hartnerné Pohóczky Krisztina
• 17.

  Oxidative damage and adduct formation I.

  - Hartnerné Pohóczky Krisztina
• 18.

  Oxidative damage and adduct formation II.

  - Hartnerné Pohóczky Krisztina
• 19.

  Chemical carcinogenesis I.

  - Hartnerné Pohóczky Krisztina
• 20.

  Chemical carcinogenesis II.

  - Hartnerné Pohóczky Krisztina
• 21.

  Chemical teratogenesis I.

  - Hartnerné Pohóczky Krisztina
• 22.

  Chemical teratogenesis II.

  - Hartnerné Pohóczky Krisztina
• 23.

  Toxicity testing I.

  - Hartnerné Pohóczky Krisztina
• 24.

  Toxicity testing II.

  - Hartnerné Pohóczky Krisztina
• 25.

  Toxicity testing III.

  - Hartnerné Pohóczky Krisztina
• 26.

  Toxicity testing IV.

  - Hartnerné Pohóczky Krisztina
• 27.

  Summary and consultation III.

  - Hartnerné Pohóczky Krisztina
• 28.

  Summary and consultation IV.

  - Hartnerné Pohóczky Krisztina

Praktika

Seminare

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Vom Institut veröffentlichter Lehrstoff

Slides of each lecture will be available for the students on Neptun Meet Street.

Skript

Empfohlene Literatur

C.D. Klassen (ed.): Casarett & Doull's Toxicology. The Basic Science of Poisons. 9th edition, McGraww-Hill, 2019.

Voraussetzung zum Absolvieren des Semesters

-

Semesteranforderungen

Students are required to take two mid-semester written tests, which are scheduled for weeks 7 and 13, approximately. These tests will contain multiple choice and short essay type questions. The average score of these two mid-semester tests (%) will be evaluated. We will offer a final grade for those reaching a mid-term result of at least 50%.

Möglichkeiten zur Nachholung der Fehlzeiten

Missed classes cannot be made up.

Prüfungsfragen

The exam includes each topic discussed during the lectures and presented in lecture slides (available in Neptun Meet Street). Those have not achieved at least 50% in mid-term tests have to take a written exam during the exam period.

Prüfer

• Hartnerné Pohóczky Krisztina

Praktika, Seminarleiter/innen