Pharmacology 3


Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2022-2023



Vorlesungen: 14

Praktika: 0

Seminare: 28

Insgesamt: 42


  • Kode des Kurses: OAK-GT3-T
  • 3 kredit
  • General Medicine
  • Clinical modul
  • autumn

OAP-GT2-T completed , OAP-MI2-T completed



Zahl der Kursteilnehmer für den Kurs:

min. 5


The general aim of the subject is to provide the medical students with all the basic information in pharmacology necessary to understand the actions of drugs and the clinical pharmacotherapy and to pass the Foreign Medical Graduate Examination in Medical Sciences. Pharmacology can be defined as the study of the manner in which the function of living systems is affected by chemical agents. Therefore, the students should be familiar with the basic knowledge of the physiological, pathophysiological and biochemical background of the pharmacological and therapeutic approaches. On the other hand, drug therapy is closely related to the clinical aspects of diseases.
The following topics will be dealt with. Pharmacology of the endocrine system: pituitary hormones, corticosteroids, reproductive system, thyroid hormones, antithyroid drugs, insulin, glucagon and oral hypoglycemic agents, vitamin D, treatment of osteoporosis. Chemotherapy: sulphonamides and trimethoprim, fluoroquinolones, beta-lactam antibiotics, tetracyclines, chloramphenicol, macrolide antibiotics, clindamycin, vancomycin, polymyxins, aminoglycosides, antituberculotics, treatment of leprosy. Antifungal drugs, antiviral agents, antiprotozoal drugs, antihelminthic agents, antiseptics and disinfectants. Pharmacogenetics, effects of age, diet and diseases on drug action. Drug interactions. Basics of toxicology.


  • 1. Corticosteroids I - Dr. Tamasikné Dr. Helyes Zsuzsanna
  • 2. Corticosteroids II - Dr. Tamasikné Dr. Helyes Zsuzsanna
  • 3. Estrogens, antiestrogens, progestins and antiprogestins - Dr. Pethő Gábor István
  • 4. Postmenopausal hormone therapy and hormonal contraceptives - Dr. Pethő Gábor István
  • 5. Androgens, anabolic steroids and antiandrogens - Dr. Pethő Gábor István
  • 6. Thyroid hormones, antithyroid drugs - Dr. Tamasikné Dr. Helyes Zsuzsanna
  • 7. Hypothalamic and pituitary hormones I - Dr. Gregus Zoltán
  • 8. Hypothalamic and pituitary hormones II - Dr. Gregus Zoltán
  • 9. Insulin, insulin analogs - Dr. Sánticsné Dr. Pintér Erika
  • 10. Oral hypoglycemic agents. Glucagon - Dr. Sánticsné Dr. Pintér Erika
  • 11. Parathyroid hormone, calcitonin, vitamin D and drug treatment of osteoporosis I - Dr. Tamasikné Dr. Helyes Zsuzsanna
  • 12. Parathyroid hormone, calcitonin, vitamin D and drug treatment of osteoporosis II - Dr. Tamasikné Dr. Helyes Zsuzsanna
  • 13. Drug interactions - Dr. Pethő Gábor István
  • 14. Future perspectives of pharmacology - Dr. Sánticsné Dr. Pintér Erika



  • 1. Basic principles of chemotherapy
  • 2. Sulfonamides and trimethoprim. Fluoroquinolones
  • 3. Antibiotics impairing bacterial cell envelope function I
  • 4. Antibiotics impairing bacterial cell envelope function II
  • 5. Antibiotics impairing bacterial cell envelope function III. Nitroimidazole drugs
  • 6. Antibiotics inhibiting protein synthesis I
  • 7. Antibiotics inhibiting protein synthesis II
  • 8. Antibiotics inhibiting protein synthesis III
  • 9. Antibiotics inhibiting protein synthesis IV
  • 10. Antituberculotic drugs. Anti-leprosy drugs
  • 11. Antifungal drugs
  • 12. Antiviral drugs I
  • 13. Antiviral drugs II
  • 14. Antiviral drugs III
  • 15. Antiprotozoal drugs I
  • 16. Antiprotozoal drugs II
  • 17. Anthelminthic drugs I
  • 18. Anthelminthic drugs II
  • 19. Antiseptics and disinfectants I
  • 20. Antiseptics and disinfectants II
  • 21. Cytotoxic/embryotoxic effects of drugs
  • 22. Drug allergy
  • 23. Pharmacogenetics, pharmacogenomics
  • 24. Effects of age, diet and disease on drug action
  • 25. Toxicology: management of the poisoned patient I
  • 26. Toxicology: management of the poisoned patient II
  • 27. Toxicology: drug intoxications I
  • 28. Toxicology: drug intoxications II

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Vom Institut veröffentlichter Lehrstoff

Materials related to the topics discussed in lectures and seminars will be available in Neptun.


Empfohlene Literatur

Rang, Dale, Ritter, Moore: Pharmacology, 9th edition, Elsevier Churchill Livingstone, 2020
B. G. Katzung (ed.): Basic and Clinical Pharmacology, 14th edition, Lange Medical Books/McGraw-Hill, 2018

Voraussetzung zum Absolvieren des Semesters

Maximum of 25 % absence allowed


There is no mid-semester test.

Möglichkeiten zur Nachholung der Fehlzeiten

Each missed seminar has to be made up for with another group in the same week.


1. Definition of pharmacology and the related subjects. Drug development
2. Drug names, drug compendia. Prescription writing
3. Drug formulations
4. Basic mechanisms of drug actions (examples of drug effects on receptors, ion channels, enzymes, carrier systems and effects mediated by physicochemical interactions)
5. Characterisation of agonist-receptor interaction: occupancy, affinity, dose-response curve, potency, efficacy
6. Significance of signal transduction mechanisms in the effects of drugs. Tachyphylaxis and tolerance to drugs
7. Mechanisms of drug antagonisms
8. Transport of drugs across membranes
9. Absorption of drugs, oral bioavailability and presystemic elimination
10. Distribution of drugs
11. Biotransformation of drugs
12. Excretion of drugs
13. Pharmacokinetics: zero and first order elimination, volume of distribution, clearance, elimination half-life, oral bioavailability, loading dose, maintenance dose
14. Cholinergic agonists and cholinesterase inhibitors
15. Muscarinic receptor antagonists
16. Neuromuscular blocking agents
17. Agents acting on the biosynthesis, storage, release and elimination of catecholamines
18. Adrenergic receptor agonists
19. Adrenergic receptor antagonists
20. Pharmacology of protein and peptide mediators, the purinergic system and nitric oxide
21. Local anesthetics
22. Histamine, antihistaminic drugs
23. Pharmacology of eicosanoids. Drugs acting on smooth muscle
24. Drugs used to treat bronchial asthma
25. Drug treatment of allergic rhinitis. Antitussives, expectorants and mucolytics
26. Calcium channel blockers
27. Drugs acting on the renin-angiotensin-aldosterone system
28. Diuretic drugs
29. Antiarrhythmic drugs
30. Drugs used to treat congestive heart failure
31. Antianginal drugs
32. Antihypertensive drugs
33. Drugs that increase regional blood flow. Drug treatment of obesity
34. Drugs used to treat hyperlipoproteinemias
35. Anticoagulants, antiplatelet drugs
36. Fibrinolytics, antifibrinolytics, hemostatic agents
37. Drugs affecting hematopoiesis
38. Antineoplastic drugs: alkylating agents, antimetabolites, microtubule-damaging drugs, topoisomerase inhibitors
39. Antineoplastic drugs: hormonal agents, cytokines, tyrosine kinase inhibitors, monoclonal antibodies, agents inducing differentiation
40. Immunosuppressants, immunomodulators, treatment of rheumatoid arthritis
41. Antianxiety and hypnotic drugs
42. Alcohols: pharmacology, toxicology
43. Antipsychotic drugs
44. Antidepressants
45. General anesthetics
46. Psychomotor stimulants and nootropic agents
47. Antiepileptic drugs
48. Drug treatment of neurodegenerative disorders
49. Drug abuse and dependence: general principles, opioids, anti-anxiety and hypnotic drugs, inhalants, ethanol
50. Drug abuse and dependence: psychomotor stimulants, psychedelics, cannabis
51. Opioid analgesic drugs: morphine and codeine
52. Opioid analgesic drugs: semisynthetic, synthetic opioids, opioid antagonists
53. Non-steroidal antiinflammatory drugs: aspirin, paracetamol
54. Non-steroidal antiinflammatory drugs: drugs other than aspirin or paracetamol
55. Adjuvant analgesics. Drugs used to treat gout. Centrally-acting muscle relaxants
56. Drugs used in the treatment of peptic ulcer
57. Emetics, antiemetics and prokinetic drugs
58. Laxatives, antidiarrhoeal agents, drug treatment of inflammatory bowel disease and paralytic ileus, digestives, drugs used in cholelithiasis
59. Serotonin, serotonin receptor agonists and antagonists
60. Hypothalamic and pituitary hormones
61. Corticosteroids
62. Estrogens, antiestrogens, progestins, antiprogestins
63. Postmenopausal hormone therapy and hormonal contraceptives
64. Androgens, anabolic steroids, antiandrogens
65. Thyroid hormones, antithyroid drugs
66. Insulin and oral hypoglycaemic agents. Glucagon
67. Parathyroid hormone, calcitonin and vitamin D, drugs used to treat osteoporosis
68. Sulphonamides and trimethoprim. Fluoroquinolones
69. Penicillins, cefalosporins
70. Carbapenems, monobactams, beta lactamase inhibitors
71. Glycopeptide antibiotics, polymixins, gramicidins, nitroimidazoles
72. Aminoglycosides. Macrolide antibiotics
73. Tetracyclines. Chloramphenicol, clindamycin, linezolid, streptogramins
74. Antituberculotic drugs. Anti-leprosy drugs
75. Antifungal drugs
76. Antiviral drugs: drugs against herpes and hepatitis viruses
77. Antiviral drugs: drugs against HIV and influenza viruses
78. Antiprotozoal drugs
79. Anthelminthic drugs
80. Antiseptics and disinfectants
81. Cytotoxic/embryotoxic effects of drugs. Drug allergy
82. Pharmacogenetics, pharmacogenomics. Effects of age, diet and disease on drug action
83. Drug interactions
84. The treatment of the intoxicated patient: decontamination, facilitation of toxicant elimination, antidote administration, supportive treatment
85. Drug intoxications: mechanisms, symptoms, treatment
86. Future perspectives of pharmacology

Upon the oral exam, 3 exam topics are chosen. In addition to these exam topics, important parts of the exam are the questions that aim at assessing the general knowledge of the student. Bad performance in this part of the exam may lead to failure regardless of the answers to exam topics.


  • Dr. Barthó Loránd
  • Dr. Pethő Gábor István
  • Dr. Pozsgai Gábor
  • Dr. Sánticsné Dr. Pintér Erika
  • Dr. Tamasikné Dr. Helyes Zsuzsanna

Praktika, Seminarleiter/innen

  • Dr. Csekő Kata
  • Dr. Horváth Ádám István
  • Dr. Sándor Zoltán
  • Dr. Sánticsné Dr. Pintér Erika
  • Dr. Tamasikné Dr. Helyes Zsuzsanna