Data
Official data in SubjectManager for the following academic year: 2024-2025
Course director
-
Boldizsár Ferenc
associate professor,
1st Department of Internal Medicine -
Number of hours/semester
lectures: 28 hours
practices: 0 hours
seminars: 0 hours
total of: 28 hours
Subject data
- Code of subject: OBA-111-E
- 2 kredit
- Biotechnology MSc
- Basic modul
- spring
Prerequisites:
OBA-107-E finished
Course headcount limitations
min. 5 – max. 200
Topic
Az alap immunológia oktatása.
Lectures
- 1. Introduction. - Németh Péter János
- 2. Molecular components of the immune system. - Németh Péter János
- 3. Recognition molecules. Recognition by MHC. - Németh Péter János
- 4. Antigen presentation and MHC restriction. - Németh Péter János
- 5. Communication between the cellular components of the immune system. - Németh Péter János
- 6. Adhesion molecules, co-receptors, cytokines, cytokine receptors. - Németh Péter János
- 7. The complement system. - Berki Timea
- 8. Innate immunity: inflammation, leukocyte migration. - Engelmann Péter András
- 9. Organization and rearrangement of the antigen receptor genes. - Balogh Péter
- 10. Primary B cell development: developmental stages and checkpoints. - Balogh Péter
- 11. T-cell development in the thymus. Stages of maturation and the role of environmental factors. - Boldizsár Ferenc
- 12. Beginning of the immune response: early stages of T/B cell interaction, CD3 complex and signal transduction, BcR signal transduction. Co-stimulation. T-dependent - Boldizsár Ferenc
- 13. Components of the humoral immune response: extrafollicular reaction and germinal center. - Balogh Péter
- 14. Immunological memory. - Balogh Péter
- 15. Effector functions of immunoglobulins. Antigen-antibody reactions. IgE mediated immunereactions. - Berki Timea
- 16. Effector mechanisms of cell-mediated immune responses: 1. Cytotoxicity, 2. Th cell-mediated macrophage activation (Delayed type hypersensitivity=DTH) - Berki Timea
- 17. Allergies and hypersensitive reactions. - Boldizsár Ferenc
- 18. Allergies and hypersensitive reactions. - Boldizsár Ferenc
- 19. Systemic and local immunity (SALT, MALT). - Németh Péter János
- 20. Suppression of the immune response. - Németh Péter János
- 21. Immunological tolerance. - Németh Péter János
- 22. Autoimmunity and autoimmune diseases. - Németh Péter János
- 23. Primary immunodeficiencies. - Balogh Péter
- 24. Acquired immunodeficiencies, pathomechanism and progression of AIDS, diagnostic and therapeutic possibilities. - Engelmann Péter András
- 25. Immunity against tumors. - Németh Péter János
- 26. Immunological aspects of organ transplantation. - Németh Péter János
- 27. Immuno-based therapies. - Németh Péter János
- 28. Protein therapies. Recombinant cytokines. Vaccine development. - Böröcz Katalin
Practices
Seminars
Reading material
Obligatory literature
nincs
Literature developed by the Department
www.immbio.hu
Notes
nincs
Recommended literature
2010 után kiadott immunológia tankönyvek
Conditions for acceptance of the semester
Részvétel az előadásokon
Mid-term exams
nincs
Making up for missed classes
nincs
Exam topics/questions
Az előadások anyaga. www.immbio.hu
Examiners
- Németh Péter János