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Education

Molecular Therapies

Data

Official data in SubjectManager for the following academic year: 2024-2025

Course director

Number of hours/semester

lectures: 14 hours

practices: 0 hours

seminars: 14 hours

total of: 28 hours

Subject data

  • Code of subject: OBH-013-T
  • 2 kredit
  • Biotechnology MSc
  • Specialty in Medical Biotechnology modul
  • autumn
Prerequisites:

-

Course headcount limitations

min. 5 – max. 50

Topic

During the course we introduce the molecular basics of modern therapeutical approaches in human medicine. We put special emphasis on recombinant protein production and the RNAi based or viral gene therapy. Furthermore, we discuss in details the gene, protein, or small molecule-based interventions from metabolic malfunctions to pulmonary diseases. Finally, we touch the future molecular technologies against infectious diseases.

Lectures

  • 1. Introduction, recombinant proteins: expression, applications - Engelmann Péter András
  • 2. RNAi-based molecular therapy - Engelmann Péter András
  • 3. Viral-based gene therapy - Engelmann Péter András
  • 4. Therapeutical approaches in neurodegenerative diseases - Engelmann Péter András
  • 5. Molecular therapies for inborn diseases - Mosdósi Bernadett
  • 6. Kinase and non-kinase inhibitors in lung cancer therapy - Balikó Zoltán
  • 7. Molecular therapeutical approaches in cardiovascular diseases - Deres László
  • 8. Molecular therapies in metabolic diseases - Kun Szilárd János
  • 9. Molecular therapies in hematological disorders - Kohl Zoltán
  • 10. Molecular therapeutical approaches in systemic autoimmune diseases - Minier Tünde
  • 11. Molecular therapies in chronic pulmonary diseases - Engelmann-Szabó Mariann
  • 12. Novel trends in vaccine development against infectious diseases - Péterfi Zoltán
  • 13. Bacteriophage therapy - Schneider György József
  • 14. Consultation - Engelmann Péter András

Practices

Seminars

  • 1. Protein replacement therapy - Engelmann Péter András
  • 2. RNA-i based molecular therapy - Engelmann Péter András
  • 3. Viral-based gene therapy - Engelmann Péter András
  • 4. Therapeutical approaches in neurodegenerative diseases - Engelmann Péter András
  • 5. Molecular therapies for inborn diseases - Mosdósi Bernadett
  • 6. Kinase and non-kinase inhibitors in lung cancer therapy - Balikó Zoltán
  • 7. Molecular therapeutical approaches in cardiovascular diseases - Deres László
  • 8. Molecular therapies in metabolic disorders - Kun Szilárd János
  • 9. Molecular therapies in hematological disorders - Kohl Zoltán
  • 10. Molecular therapeutical approaches in systemic autoimmune diseases - Minier Tünde
  • 11. Molecular therapies in chronic pulmonary diseases - Engelmann-Szabó Mariann
  • 12. Novel trends in vaccine development against infectious diseases - Péterfi Zoltán
  • 13. Bacteriophage therapy - Schneider György József
  • 14. Consultation - Engelmann Péter András

Reading material

Obligatory literature

Literature developed by the Department

MS Teams

Notes

Recommended literature

Conditions for acceptance of the semester

Írásbeli vizsga

Mid-term exams

None

Making up for missed classes

None

Exam topics/questions

None

Examiners

  • Engelmann Péter András

Instructor / tutor of practices and seminars

  • Balikó Zoltán
  • Deres László
  • Engelmann Péter András
  • Engelmann-Szabó Mariann
  • Kohl Zoltán
  • Kun Szilárd János
  • Minier Tünde
  • Mosdósi Bernadett
  • Péterfi Zoltán
  • Schneider György József
Rólunk