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Student Researchers' Society Topics

Co-supervisor: NAGY-RADVÁNYI, Lilla

Honey is applied both in traditional and official healing practices. However, the medicinal value of different types of honeys may vary to a large degree. The research student should determine the active compounds of various herbal honeys, and – possibly – their marker substances. A further goal of the study is to analyze the antioxidant and/or antimicrobial activity of unifloral honeys in various in vitro test systems, as well as to compare the biological activity of honeys of different botanical origin.
 

Plants appear sporadically in different ecological habitats, which conditions can influence the morphological, histological and phytochemical characters of the medicinal plant species. The possible polymorphism plays an important role in the correct identification of the taxa, reffering to their recommended collection place. The aim of this study is to collect plant taxa from various ecological areas, and to analyse the similarities and differences among the selected populations. This comparative study consists of field work, as well as of histological and phytochemical analyses. 

Ethnobotany deals with the traditional knowledge and use of the medicinal plants in isolated regions. Several areas are not provided by permanent medical service or pharmacy, therefore rural people have to know and collect the plants from their environment in their everyday life. The study includes field work to collect these data by interviews, to find new taxa or drug parts for further laboratory (histological and phytochemical) analyses. These studies are of primary importance in the search for new indications and use of some plants, which are currently not supported by scientific evidence.

Co-supervisor: Dr. PAPP, Nóra

Histological features can play an essential role in correct identification of medicinal plants and their drug parts. This research will focus on the histological characters of vegetative or generative plant parts, investigated by various microtechniques, including the proper collection and storage of selected plant samples, the preparation of leaf surface casts and sections, as well as mounting and dyeing preparations. The preparations will be studied with light microscopy, and their histological data will be analyzed by different softwares.

Today more and more people are affected by respiratory infections and inflammations. In these cases essential oils are used by inhalation, but this application is mainly based on ethnomedicinal experiences. Therefore the investigation of the anti-inflammatory effect of essential oils is required, which is one of the most important fields of drug development and pharmacy. The investigation will focus on the respiratory anti-inflammatory activity of essential oils in animal model (mice) and the student can learn several pharmacological methods. The student’s work will be organized at the Department of Pharmacognosy and the Institute of Pharmacology and Pharmacotherapy.

Co-supervisor: Dr. ÁCS, Kamilla

Antibiotic resistance poses a considerable problem in public health, therefore the search for new antimicrobial agents is essential. Essential oils have various effects, their antibacterial and antifungal activities have also been reported. Throughout history, medicinal plants containing essential oil have been used against various diseases, e.g. the spread of plague (black death) used to be prevented with burning of essential oil plants. In the course of investigations the student will learn the process of essential oil distillation, then the most commonly used antimicrobial assays of essential oils, such as tube-dilution and direct bioautography. The aim of our work is to find new and effective antibacterial and/or antifungal essential oils. The student’s work will be organized at the Department of Pharmacognosy and the Institute of Medical Microbiology and Immunology.

We are surrounded by a variety of poisonous plant species, which can cause mild to severe intoxications when different plant parts or extracts enter the body. In most cases the active compounds of toxicologically important plant species are known, however, the concentration of these substances may vary as a function of plant organ, habitat or season. The research will focus on determining the toxicological importance of a selected poisonous plant species (based on case studies), and will include the phytochemical analysis of samples from various locations and time periods. Another option is the survey of poisonous plant species in a selected area (natural vegetation or residential area), highlighting their toxicological significance.

Co-supervisor: BALÁZS, Viktória Lilla

Co-supervisor: Dr. GULYÁS, Gergely

Curcumin is a hot topic in contemporary research, as it shows very interesting biological effects regarding its tumor disease related activities, beside being a well known antioxidant and radical scavenger. Carotenoids, on the other hand, are a traditional research focus in the Research Group for Carotenoids with long tradition at our university. The covalent coupling of the two mentioned molecular moieties might lead to the enhancement in the antioxidant effects and possible further advantageous synergistic interactions widening the spectra of the individual biological properties. To be able to examine this proposed combination, the organic synthesis of the conjugates is underway and provides the prospective student an insight into the organic synthesis methods in theory and in practice.