Pathology for Dental Students 2

Data

Official data in SubjectManager for the following academic year: 2024-2025

Topic

There is a special emphasis during the course on the clinicopathological view of the diseases, i.e., understanding the relationship of the clinical symptoms, macroscopical and microscopical changes of the diseased organs. By the end of the academic year, a basic clinicopathological affinity and competence in differential diagnosis is required of the students. Fundamentals and major examples of specific, organ pathology are discussed.

Since this is a curriculum designated with specific regard to dentistry students, special emphasis will be placed on the oral pathology and head-and-neck pathology chapters.

The systemic pathology course involves the major fields of organ pathology: pulmonary pathology, haematopathology, gastrointestinal pathology, pathology of the liver, pancreas and biliary system, pathology of the skin, cardiovascular pathology, oral pathology, pathology of the head and neck, pathology of the endocrine organs, nephropathology, pathology of male and female genital system and breast pathology.

Pathology education of dentistry students consists of 28 lectures and 28 histopathology seminars (14 practices) with the emphasis on oral pathology. The education during the second semester is carried out by the leader and colleagues of the Oral Pathology Unit (Faculty) of the Pathology Department.

The third-year students are expected to acquire the pathogenesis, the macroscopy and partly the microscopy of the main pathological changes which occure in this region. This reference knowledge could be used for the ongoing dental studies and especially later in consultations with the oral pathologists. The attendance to the Oral Pathology course and the knowledge picked up there –beside the general requirements- are obligatory to the approval of the two semesters.

Lectures

• 1. I. PATHOLOGY OF THE RESPIRATORY SYSTEM (2 LECTURES) Pathology of the Lung 1. - Vida Livia
• 2. Pathology of the Lung 2. - Vida Livia
• 3. II. DERMATOPATHOLOGY (2 LECTURES) 3. Dermatopathology I: common skin lesions occuring in the head and neck region. - Gyömörei Csaba
• 4. Dermatopathology II: systemic skin diseases with oral cavity manifestations - Gyömörei Csaba
• 5. III. HAEMATOPATHOLOGY (2 LECTURES) Ontogenesis of the lymphoid cells. General characteristics of lymphomas. - Kajtár Béla
• 6. Hematological malignancies of the head and neck region. - Kajtár Béla
• 7. IV. PATHOLOGY OF THE GASTROINTESTINAL TRACT (2 LECTURES) 7. Diseases of the esophagus and stomach - Bogner Barna István
• 8. Pathology of the small and large intestines - Bogner Barna István
• 9. V. CARDIOVASCULAR PATHOLOGY (4 LECTURES) Ischaemic heart diseases. - Tornóczki Tamás
• 10. Endocarditis, myocarditis - Tornóczki Tamás
• 11. Congenitalis heart diseases Cardiomyopathies - Tornóczki Tamás
• 12. Vasculitis, types, vascular tumors - Tornóczki Tamás
• 13. VI. ORAL PATHOLOGY (7 LECTURES) Infective disorders of oral cavity - Semjén Dávid
• 14. Non infective disorders of the oral cavity. - Semjén Dávid
• 15. Benign epithelial lesions of the oral cavit - Semjén Dávid
• 16. Malignant epithelial neoplasms of the oral cavity. Pathogenetic role of HPV. - Tornóczki Tamás
• 17. Pathology of the salivary glands. 1. - Tornóczki Tamás
• 18. Pathology of the salivary glands. 2. - Tornóczki Tamás
• 19. Mesenchymal lesions of the oral cavity - Tornóczki Tamás
• 20. VII. PATHOLOGY OF THE ENDOCRINE GLANDS (2 LECTURES) 20. Hypophysis tumors. Pathology of the thyroid gland I (developmental anomalies, hyperplasias, thireoiditides) - Tornóczki Tamás
• 21. Pathology of the thyroid gland II (neoplaias). Pathology of the parathyroid glands. Pathology of the adrenals. - Tornóczki Tamás
• 22. VIII. NEPHRO- AND UROPATHOLOGY (2 LECTURES) Pathology of kidney tumours. Kidney failure. - Kereskai László
• 23. Inflammations and tumors of the urinary system. - Kereskai László
• 24. IX. PATHOLOGY OF THE LIVER, PANCREAS AND THE BILIARY SYSTEM (2 LECTURES) Liver diseases - Tornóczki Tamás
• 25. Pathology of the pancreas and the biliary tract. - Tornóczki Tamás
• 26. X. PATHOLOGY OF THE MALE, FEMALE GENITALIA AND THE BREAST (3 LECTURES) 26. Pathology of the testis, epididymis and prostate. - Semjén Dávid
• 27. Pathology of the ovaries and uterus. - Kálmán Endre
• 28. Pathology of the breast. - Kálmán Endre

Practices

Seminars

• 1. Pathology of the respiratory system
• 2. Pathology of the respiratory system
• 3. Dermatopathology
• 4. Dermatopathology
• 5. Haematopathology
• 6. Haematopathology
• 7. Pathology of the GI tract
• 8. Pathology of the GI tract
• 9. Cardiovascular Pathology
• 10. Cardiovascular Pathology
• 11. Pathology of the oral cavity 1
• 12. Pathology of the oral cavity 1
• 13. Pathology of the oral cavity 2
• 14. Pathology of the oral cavity 2
• 15. Pathology of the oral cavity 3
• 16. Pathology of the oral cavity 3
• 17. Pathology of the oral cavity 4
• 18. Pathology of the oral cavity 4
• 19. Pathology of the endocrine glands
• 20. Pathology of the endocrine glands
• 21. Nephropathology
• 22. Nephropathology
• 23. Liver, pancreas pathology
• 24. Liver, pancreas pathology
• 25. Pathology of the male and female genital tract. Breast pathology
• 26. Pathology of the male and female genital tract. Breast pathology
• 27. Consultation
• 28. Consultation

Reading material

Obligatory literature

Robbins: Basic Pathology Medicina 2014.

Literature developed by the Department

Tornóczky, Kajtár: Oral Pathology Histology Notes (also available here: http://aok.pte.hu/hu/egyseg/oktatasianyagok/230 limited amounts of printed version is available at our secretary office)

Lecture slides are found on the homepage of Department of Pathology.

Notes

Recommended literature

V. Kumar, A. Abbas, J. Aster: Robbins Basic Pathology, 10th ed. Elsevier, ISBN: 978-0-323-3-53175, 2017

Tornóczky, Kajtár: Oral Pathology Histology Notes (also available here: http://aok.pte.hu/hu/egyseg/oktatasianyagok/230 limited amounts of printed version is available at our secretary office)

Edward Odell: Cawson’s Essentials of Oral Pathology and Oral Medicine. 9th Ed., Elsevier, 2017 ISBN, 978-0443-10365-0

Antonio Cardesa, Pieter J. Slootweg, Nina Gale, A. Franchi: Pathology of the Head and Neck. Springer-Verlag Berlin Heidelberg, 2016, ISBN 978-0-702-0-49828

Sook-Bin Woo: Oral Pathology: A comprehensive atlas and text. Esevier-Saunders, 2012, ISBN:978-1-4377-2226-0

JA. Regezi, JJ. Sciubba, RCK. Jordan: Oral Pathology. Clinicopathlogical correlations. 6th Edition, Elsevier, 2012, ISBN: 978-1-4557-0262-6

Lecture slides are found on the homepage of Department of Pathology.

Conditions for acceptance of the semester

Absences exceeding 15% of the practical classes will result in not signing the gradebook. Maximum absence: 2 practices. Final exam for the dentist students includes two slides and 2 exam questions.

Mid-term exams

Final exam for the dentist students includes two slides and 2 exam questions.

Making up for missed classes

Each missed seminar has to be made up for with another group in the same week.

Exam topics/questions

SLIDES

I. PATHOLOGY OF THE RESPIRATORY SYSTEM

1. CMV pneumonitis

2. Carcinoma microcellulare pulmonum

3. Carcinoma planocellulare pulmonum

II. DERMATOPATHOLOGY

4. Seborrheic keratosis

5. Basal cell carcinoma

6. Nodular melanoma

7. Bullous pemphigoid

8. Psoriasis

III. HAEMATOPATHOLOGY

9. Toxoplasma lymphadenitis

10. Follicular lymphoma

11. CLL/SLL infiltration in lymph node

12. Diffuse large B-cell lymphoma

13. Hodgkin lymphoma

14. CML, CP smear

IV. PATHOLOGY OF THE GASTROINTESTINAL TRACT

15. Helicobacter pylori infection (Warthin-Starry)

16. Coeliac disease– subtotal/total villous arophy (Marsh 3c)

17. Carcinoid of the appendix

18. Rectal adenocarcinoma

V. CARDIOVASCULAR PATHOLOGY

19. Viral myocarditis

20. Arteritis temporalis

21. Kaposi sarcoma

VI-IX. ORAL PATHOLOGY

22. Squamous cell papilloma

23. Keratoacanthoma

24. Squamous cell carcinoma

25. Nasopharyngeal carcinoma (lymphoepithelial carcinoma)

26. Keratinizing squamous cell metaplasia

27. Epulis (peripheral giant cell granuloma)

28. Pyogenic granuloma

29. Buccal fibroma

30. Granular cell tumor (Abrikosov-tumor)

31. Orofacial actinomycosis

32. Sialoadenitis chronica in the submandibular gland (Küttner-tumor), sialolithiasis

33. Lymphoepithelial cyst (intraparotid)

34. Mucocele (extravasation type)

35. Focus forming lymphocytic sialoadenitis in the minor salivary gland (Sjögren syndrome)

36. Pleiomorphic adenoma

37. Warthin tumor (cystadenoma papillare lymphomatosum)

38. Adenoid cystic carcinoma

39. Mucoepidermoid carcinoma

40. Fibrous dysplasia of the jaw

41. Ameloblastoma (unicystic type)

42. Oral lichen

43. Verrucous type squamous cell carcinoma

44. Plasma cell granuloma (epulis)

45. Radicular cyst

46. Odontogen keratocyst (keratocystic odontogen tumor)

47. Crohn’ s disease, oal caviy

48. Salivary gland MALT lymphoma

49. BION (bisphosphonate induced osteonecrosis)

50. Plasma cell myeloma, jaw

51. Pemphigus vulgaris, oral cavity

52. Leukoplakia: in situ carcinoma

53. Oral candidiasis

X. ENDOCRINOPATHOLOGY

54. Papaillary carcinoma of the thyroid gland

55. Basedow-Graves disease

56. Hashimoto’s-thyreoiditis

57. Parathyroid adenoma

58. Phaeochromocytoma

XI. NEPHRO- AND UROPATHOLOGY

59. Clear cell renal cell carcinoma

60. Urothelial carcinoma of the renal pelvis

XII. PATHOLOGY OF THE LIVER, PANCREAS AND THE BILIARY SYSTEM

61. HBs-antigen positivity (Shikata)

62. Chronic hepatitis

63. Hepatocellular carcinoma in cirrhotic liver

XIII. PATHOLOGY OF THE MALE, FEMALE GENITALIA AND THE BREAST

64. Prostate adenocarcinoma

65. Seminoma

66. Endometrial adenocarcinoma, curettage

67. Serous papillary cystadenocarcinoma of the ovaries

68. Invasive ductal carcinoma

THEORETIAL QUESTIONS

I. PATHOLOGY OF THE RESPIRATORY SYSTEM

1. Diseases of the upper airways.

2. Infections of the lower airways (nosocomial, community acquired and opportunistic infections). ARDS

3. Chronic obstructive lung diseases: general caracteristics, types

4. Malignant tumors of the lung

II. DERMATOPATHOLOGY

5. Melanocytic lesions

6. Epithelial tumors of the skin

7. Inflammatory skin diseases

III. HAEMATOPATHOLOGY

8. Reactive lymph node changes

9. Lymphomas in the head and neck region

10. Myeloid neoplasias

IV. PATHOLOGY OF THE GASTROINTESTINAL TRACT

11. Diseases of the oesophagus

12. Pathology of the stomach

13. Pathology of the small intestines

14. Colorectal pathology

V. CARDIOVASCULAR PATHOLOGY

15. Angina pectoris és chronic ischemic heart disease, sudden cardiac death

16. Clinicopathology of acute myocardial infarction

17. Pathology of valvular disorders (inflammatory and degenerative)

18. Cardiomyopathies, cardiac tumors

19. Myocarditides, pathology of the pericardium

20. Congenital heart diseases

21. Arterioclerosis, types and clinicopathology of aneurysms

22. Pathogenesis, classification and clinicopathology of vasculitides, vascular tumors

VI. ORAL PATHOLOGY

23. Infective inflammatory diseases of the oral mucosa

24. Non infective inflammatory diseases of the oral mucosa

25. Benign epithelial lesions of the oral mucosa

26. Role of the HPV subtypes in the pathogenesis of benign and malignant lesions of the oral mucosa

27. Precancerous conditions. Leukoplakia and its differential diagnosis. Erythroplakia.

28. Malignant epithelial neoplasms of the oral cavity: histology types, localisation and pathogenesis

29. Benign mesenchymal lesions of the oral cavity and the jaws

30. Malignant mesenchymal lesions of the oral cavity and the jaws

31. Inflammatory lesions of the salivary glands: sialoadenitis, sialolithiasis, Mikulicz syndrome, Sjögren syndrome.

32. Tumor-like lesions of the salivary glands and oral mucosa.

33. Benign tumors of the salivary gland

34. Malignant tumors of the salivary gland

35. Odontogenic and non odontogenic cysts

36. Odontogenic tumors

VII. PATHOLOGY OF THE ENDOCRINE SYSTEM

37. Anterior lobe pituitary tumors. Congenital anomalies of the thyroid gland, conditions associated with hyperplasia

38. Thyroiditis, thyroid neoplasias

39. Hyperplasia, adenoma of the parathyroid gland

40. Adrenal gland hyperplasia, atrophy, tumors of the adrenal cortex. Tumors of the adrenal medulla.

VIII. NEPHRO- AND UROPATHOLOGY

41. Cystitides, tumors of the bladder and ureter

IX. PATHOLOGY OF HTE LIVER, PANCREAS AND THE BILIARY SYSTEM

42. Pathology of the liver

43. Diseases of the biliary tract and the pancreas

X. PATHOLOGY OF THE MALE, FEMALE GENITALIA AND THE BREAST

44. Prostate adenocarcinoma (pathogenesis, morphology, screening, diagnosis)

45. Testicular tumors, classification, tumor markers

46. Carcinoma of the cervix (pathogenesis, pathomorphology, screening)

47. Epithelial benign and malignant tumors of the uterine corpus. Mesenchymal neoplasms of the uterus.

48. Cysts and tumors of the ovaries (surface epithelial, germ cell tumors, sex cord stromal tumors, metastases)

49. Mastitides (lactational, ductal ectasis, fat necrosis, galactocele), mastopathies (fibrocystic changes). Fibroepithelial tumors

50. Carcinoma of the breast: pathogenesis, types, prognosis

51. Prostate hyperplasia: causes, symptoms, therapy

Comment: The Department of Pathology reserves the right to propose minor modifications in the curriculum

Examiners

• Bogner Barna István
• Gyömörei Csaba
• Kajtár Béla
• Kálmán Endre
• Kereskai László
• Pap Anita
• Semjén Dávid
• Tornóczki Tamás
• Vida Livia

Instructor / tutor of practices and seminars

• Bogner Barna István
• Gyömörei Csaba
• Kálmán Endre
• Pap Anita
• Semjén Dávid
• Tornóczki Tamás
• Vida Livia