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Education

Translational Cardiovascular Research: From Bench to Bedside

Data

Official data in SubjectManager for the following academic year: 2024-2025

Course director

Number of hours/semester

lectures: 0 hours

practices: 0 hours

seminars: 12 hours

total of: 12 hours

Subject data

  • Code of subject: OAF-SMS-T
  • 1 kredit
  • General Medicine
  • Optional modul
  • spring
Prerequisites:

OAA-EL1-T finished , OAP-KN1-T finished

Course headcount limitations

min. 5 – max. 40

Topic

The main goal of the course is to provide an overview of molecular mechanisms governing the development of cardiovascular diseases, up-to-date diagnostic and therapeutic approaches of non-invasive and interventional cardiology, and future possibilities of cardiac surgery. Introduction to translational cardiovascular research gives a unique opportunity for those students, who are interested in innovative, novel diagnostic and therapeutic approaches in the field of cardiology.

Lectures

Practices

Seminars

  • 1. Acute coronary syndrome, molecular mechanisms of ischemia-reperfusion injury - Szokodi István
  • 2. Molecular mechanisms involved in the development of heart failure - Szokodi István
  • 3. Cardiac contractility in heart failure - Szokodi István
  • 4. Novel mechanisms involved in the regulation of cardiac contractility - Szokodi István
  • 5. Hemodynamic parameters in heart disease - Kónyi Attila
  • 6. Novel diagnostic tools of interventional cardiology - Kónyi Attila
  • 7. Novel revascularisation approaches of interventional cardiology - Kónyi Attila
  • 8. Non-pharmacological treatment of heart failure - Kónyi Attila
  • 9. Role of echocardiography and cardiac MRI in the diagnostics of heart diseases - Gaszner Balázs (Kardio)
  • 10. New trends in cardiac surgery - Lénárd László 1991 (Szívcentrum)
  • 11. Novel gene and cell therapies in heart failure - Szokodi István
  • 12. Exam - Szokodi István

Reading material

Obligatory literature

Literature developed by the Department

Hand-out.

Notes

Recommended literature

Opie LH; (ed.): Heart Physiology: from Cell to Circulation, 4th edition, Lippincott-Raven, Philadelphia, PA, 2003 (ISBN-10: 0781742781);

Darovic GO (ed.): Hemodynamic Monitoring: Invasive and Non-Invasive Clinical Application, 3rd edition, WB Saunders Company, Philadelphia, PA, 2002 (ISBN 0-7216-9293-1)

Conditions for acceptance of the semester

A short presentation of optional choice on a related topic.

Mid-term exams

The course will end with a test exam (last seminar or as agreed).

Making up for missed classes

Individual consultation.

Exam topics/questions

Pathomechanism of acute myocardial infarction

Ischemia-reperfusion injury, pre- and postconditioning

Physiological cardiac hypertrophy

Adverse left ventricular remodeling

Determination of systolic and diastolic function using echocardiography

Evaluation of myocardial viability using cardiac MRI

Valve surgery, TAVI

New diagnostic approaches of interventional cardiology

New therapeutic approaches of interventional cardiology

Examiners

Instructor / tutor of practices and seminars

  • Gaszner Balázs (Kardio)
  • Kónyi Attila
  • Lénárd László 1991 (Szívcentrum)
  • Szokodi István
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