Institute of Physiology report
The International Neuroscience Conference (INC) was held on January 25-26, 2024, in the PTE Grastyán Endre theoretical building. It was an outstanding scientific event, where novel and pioneering results were presented in the form of plenary lectures, symposia, and posters. Renowned international scientists presented their latest results, further emphasizing the importance of Hungarian neuroscience research within the international community.
The presidents of the conference organized by the Faculty of Medicine were Prof. Dr. Zsuzsanna Helyes and Prof. Dr. Dóra Zelena. Dr. Péter Buzás and Dr. Kristóf László from the Institute of Physiology participated in the organizing committee. 430 participants from different parts of the world came to the event. Prof. Dr. György Buzsáki, Prof. Dr. Patricia Churhland, Dr. Christof Koch, Prof. Dr. Joseph LeDoux, and Prof. Dr. Tamás Kozicz from the USA; Dr. Daniela Jezova and Dr. Jan Bakos from Slovakia; Prof. Dr. Jes Olessen from Denmark, Dr. Albert Gidon and Dr. Dirk Feldmeyer from Germany; Dr. Ulrike Grünert and Prof. Dr. Paul R. Martin from Australia and Prof. Dr. Petri Ala-Laurila from Finland came to give a presentation.
The staff of the Institute of Physiology participated in the conference with 3 presentations, 23 posters and as organizers.
Lectures:
- Prof. Dr. László Lénárd: The Hungarian Neuroscience Society 30 years ago.
- Kitti Mintál: Autism Spectrum Disorder associated behavioral symptoms and their relationship with the microbiome. (Kitti Mintál, Attila Tóth, Edina Hormay, Béla Kocsis, Kristóf László, Anita Bufa, Tamás Marosvölgyi, Renáta Cserjesi, Zoltán Vizvári, László Lénárd, Zoltán Karádi)
- Dr. Kristóf László: The intraamydaloid oxytocin ameliorates some autistic-like symptoms in valproate-induced autism rodent model. (K. László, D. Vörös, O. Kiss, B. László, T. Ollmann, L. Péczely, K. Mintál, A. Tóth, A. Kovács, O. Zagoracz, E. Kertes, V. Kállai, B. Berta, Z. Karádi, L. Lénárd)
Symposium organizers:
- Dr. Kristóf László and Dr. Attila Tóth: Symposium II. Preclinical examination of autism spectrum disorder
- Prof. Dr. Béla Völgyi, Dr. Ildikó Telkes, Dr. Tamás Kovács-Öller: Symposium V. Information processing in the early visual system; retina and retinorecipient brain centers
Posters:
- Szidónia Farkas, Adrienn Szabó, Viktor Jasper, Kinga Nyers-Marosi, Bence Petrovai, István M. Ábrahám1, Tamás Kovács, Dóra Zelena: Manipulating the cholinergic neurons in Alzheimer’s disease: validation of a mouse model.
- Dorottya Várkonyi, Csilla Lea Fazekas, Choi Muyong, Dóra Zelena: Unravelling the Dynamics of Thermoregulation in the Triple Transgenic Mouse Model of Alzheimer’s Disease.
- Csilla Lea Fazekas, Peter Karailiev, Pedro Correia, Krisztina Bánrévi, Daniela Jezova, Dóra Zelena: Altered gene expression of barrier molecules in a rat model of posttraumatic stress disorder contributes to vulnerability.
- Ildikó Telkes, Katalin Fusz, Tibor Zoltán Jánosi, Péter Kóbor, Paula Lily Hirsch, Abdurrahman ElZafarany, Kristóf László, Péter Buzás: Retinal cell mosaics in the valproate-induced rat model of autism spectrum disorder.
- Katalin Fusz, Ildikó Telkes, Tibor Zoltán Jánosi, Péter Kóbor, Kristóf László, Péter Buzás: Changes of amygdalar tyrosine hydroxylase and parvalbumin immunoreactive elements in the valproate-induced model of autism.
- Rita Gálosi, Gábor Kriszta, Éva Borbély, Ádám I. Horváth, Valéria Tékus, Nikolett Szentes, Zsuzsanna Helyes: Brain regions activated during inflammatory and noninflammation phases of chronic pain in a rheumatoid arthritis mouse model.
- István Szabó, Zsófia Csizek, Eszter Mikó-Baráth, Anna Budai, András Frigyik, Ágota Pusztai, Vanda Á. Nemes, László Závori, Diána Fülöp, András Czigler, Kitti Szabó-Guth, David Piñero, Péter Buzás, Gábor Jandó: Optimizing Stereovision Test Combinations for Amblyopia Screening in Children: A Perceptron Model Approach.
- Edina Hormay, Kitti Mintál, Réka Bettina László, István Szabó, Attila Tóth, Kristóf László, Nina Győrfi, László Lénárd, Zoltán Karádi: Long term saccharose consumption associated activity of limbic forebrain glucose-monitoring neurons: A pilot study in the rat.
- Erika Kvak, Szidónia Farkas, Dóra Zelena: Application of dehydroepiandrosterone as a neuroprotective agent for the therapy of Alzheimer’s disease in a mouse model.
- Evelin Szabó, Anita Kovács, Dóra Zelena: Examining the combined effect of fast acting insulin and fasting on male and female Wistar rats at the beginning of the light and dark cycles.
- Erzsébet Kövesdi, Laura Mundrucz, Attila Gyéresi, Máté Deák, Balázs Gaszner, Andy Pironet, Rudi Vennekens, Viktória Kormos, Miklós Kecskés: Anticonvulsant effect of the nonsteroidal anti-inflammatory drug meclofenamate via TRPM4 inhibition.
- Áron Kolozsvári, Szilárd Szőcs, Nóra Henn-Mike, Ágnes Agócs-Laboda, Klaudia Barabás, Csaba Varga: Electrophysiological and immunohistochemical comparison of the dentate gyrus projecting principal cells in the lateral and medial entorhinal cortex.
- Olga Zagorácz, Tamás Ollmann, László Péczely, Kristóf László, Anita Kovács, Beáta Berta, Veronika Kállai, Erika Kertes, Dávid Vörös, Daniella Dusa, Ádám Szábó, László Lénárd: Neuropeptide QRFP enhances memory in passive avoidance paradigm.
- Vanda Á. Nemes, János Radó, Eszter Mikó-Baráth, Péter Buzás, Gábor Jandó: Navigating the depths of crossed and uncrossed binocular disparities in visual short-term memory.
- János Radó, Eszter Mikó-Baráth, Péter Hegyi, Vanda Á. Nemes, Péter Buzás, Gábor Jandó: Assessment of various dynamic random dot stimuli for the electrophysiological examination of binocularity – towards a standardized clinical protocol.
- Dávid Vörös, Orsolya Kiss, Tamás Ollmann, Kitti Mintál, László Péczely, Olga Zagoracz, Erika Kertes, Veronika Kállai, Bettina Réka László, Beáta Berta, Attila Tóth, László Lénárd, Kristóf László: Effect of intraamygdaloid oxytocin on social interaction in valproate-induced autism model.
- Anita Kovács, Evelin Szabó, Kristóf László, László Lénárd, Zsuzsanna Tóth, Balázs Gaszner, Viktória Kormos, Dóra Zelena: The role of prolactin-releasing peptide (PrRP) in the development of depressive-like symptoms in rats.
- Prabhat Kumar, Csilla Lea Fazekas, Pedro Correia, Dóra Zelena: Glucose transporter 2 positive cells in the medial prefrontal cortex: unravelling their impact on posttraumatic stress disorder.
- Adrienn Szabó, Erika Kvak, Dóra Zelena: Social Behavior in the Absence of Uncoupling Protein 2 (UCP2).
- Beáta Berta, Erika Kertes, Olga Zagoracz, László Péczely, Tamás Ollmann, Kristóf László, Veronika Kállai, Ádám Szabó, László Lénárd: Effect of D1-like dopamine receptor agonist on the hedonic evaluation in the prefrontal cortex.
- Erika Kertes, László Péczely, Beáta Berta, Kristóf László, Tamás Ollman, Veronika Kállai, Olga Zagorácz, Anita Kovács, Ádám Szabó, Omid Afkhami Ardakani, László Lénárd: The role of substance P, senktide, and neurokinin receptors of the rat globus pallidus in learning in the Morris water maze test.
- Alexandra Júlia Hencz, Andor Magony, Gábor Szilágyi, József Pál, Attila Sík: The impact of hypoxia and hyperoxia on the number of compacted neurons and brain activity.
- Dorottya Wiegand, Ágota Nikl, Vanda Á. Nemes, Gábor Jandó, Adrienne Csutak, Balázs Patczai, Eszter Mikó-Baráth: Association between visual impairment, metabolic factors, and hip fractures in elderly patients.
Best Poster Avard winner:
- Szidónia Farkas, Adrienn Szabó, Viktor Jasper, Kinga Nyers-Marosi, Bence Petrovai, István M. Ábrahám1, Tamás Kovács, Dóra Zelena: Manipulating the cholinergic neurons in Alzheimer’s disease: validation of a mouse model.
The 7th Hungarian Neuroscience Doctoral Conference (HuNDoC) for undergraduates, graduate students and junior postdoctoral fellows took place on January 24. It was a fun filled day of good company, uplifting speeches, workshops, and most of all fascinating science. At the HuNDoC conference, there was an opportunity to have an open discussion with one of the greatest Hungarian neuroscientists, Prof. György Buzsáki (USA). One of the members of the organizing committee was Dr. Szilárd Szőcs, a staff member of the Institute of Physiology.
Posters:
- Abdurrahman ElZafarany, Katalin Fusz, Tibor Zoltán Jánosi, Paula Lily Hirsch, Péter Kóbor, Kristóf László, Ildikó Telkes, Péter Buzás: Validation of a trainable pixel classifier for the detection of neurons in flat-mounted retinas.
- Szidónia Farkas, Adrienn Szabó, Viktor Jasper, Kinga Nyers-Marosi, Bence Petrovai, István M Ábrahám, Tamás Kovács and Dóra Zelena: Manipulating the cholinergic neurons in Alzheimer's disease: validation of a mouse model.
- Edina Hormay, Kitti Mintál, Réka Bettina László, István Szabó, Attila Tóth, Kristóf László, Nina Győrfi, László Lénárd, Zoltán Karádi: Different aspects of the taste reactivity test to interpret gustatory responses elicited organismic changes.
- Áron Kolozsvári, Szilárd Szőcs, Nóra Henn-Mike, Ágnes Agócs-Laboda, Klaudia Barabás, Csaba Varga: Electrophysiological and immunohistochemical comparison of the dentate gyrus projecting principal cells in the lateral and medial entorhinal cortex.
- Prabhat Kumar, Csilla Lea Fazekas, Pedro Correia, Dora Zelena: Glucose transporter 2 positive cells in the medial prefrontal cortex: unravelling their impact on posttraumatic stress disorder.
- Erika Kvak, Szidónia Farkas, Dóra Zelena: Application of dehydroepiandrosterone as a neuroprotective agent for the therapy of Alzheimer’s disease in a mouse model.
- Kitti Mintál, Attila Tóth, Edina Hormay, Béla Kocsis, Kristóf László, Anita Bufa, Tamás Marosvölgyi, Renáta Cserjesi, Zoltán Vizvári, László Lénárd, Zoltán Karádi: Autism spectrum disorder associated behavioral symptoms and their relationship with the gastrointestinal microbiome.
- Erzsébet Kövesdi, Laura Mundrucz, Attila Gyéresi, Máté Deák, Balázs Gaszner, Andy Pironet, Cecília Szekeres-Paraczky, Zsófia Maglóczky, Péter Gombás, Rudi Vennekens, Viktória Kormos and Miklós Kecskés: Anticonvulsant effect of the nonsteroidal anti-inflammatory drug meclofenamate via TRPM4 inhibition.
- Adrienn Szabó, Erika Kvak, Dóra Zelena: Social Behavior in the Absence of Uncoupling Protein 2 (UCP2).
- István Szabó, Zsófia Csizek, Eszter Mikó-Baráth, Anna Budai, András Frigyik, Ágota Pusztai, Vanda Á. Nemes, László Závori, Diána Fülöp, András Czigler, Kitti Szabó-Guth, David Piñero, Péter Buzás, Gábor Jandó: Enhancing Pediatric Amblyopia Screening: Unraveling Optimal Stereovision Test Combinations with a Perceptron Model.
- Kitti Szabó-Guth, János Radó, Péter Hegyi, Eszter Mikó-Baráth, Gábor Jandó: Ensuring Visual Acuity Measurement Reliability in Cases of Reduced Visual Acuity: A Preliminary Study Using Bangerter Foils.
- Dávid Vörös, Orsolya Kiss, Tamás Ollmann, Kitti Mintál, László Péczely, Olga Zagoracz, Erika Kertes, Veronika Kállai, Bettina Réka László, Beáta Berta, AttilaToth, László Lénárd and Kristóf László: Sulpirid blocks the anxiolytic effect of oxytocin in elevated plus maze test.
- Olga Zagorácz, Tamás Ollman, László Péczely, Kristóf László, Anita Kovács, Beáta Berta, Veronika Kállai, Erika Kertes, Dávid Vörös, Daniella Dusa, Ádám Szábó, László Lénárd: Neuropeptide QRFP enhances memory in passive avoidance paradigm.
Written by Dr. Katalin Fusz
Photo: Dávid Verébi and Dr. Katalin Fusz