Advanced Physiology 1

Data

Official data in SubjectManager for the following academic year: 2026-2027

Topic

Discussion of physiological topics, that not belong to the core subject (based on real examples and case studies). The aim of the subject is to understand the deep, advanced physiological knowledge and complete the core subject. That develops the problem-solving skills necessary in the clinical practice and/or during scientific research. Furthermore, it can help to understand another subjects (pathophysiology, pharmacology) based on physiology as well. The course can be useful for dentistry and pharmacy students as well, since numerous topics are realted to dentistry or pharmacy as well. The course can contribute to the practical application of evidence based medicine, as well as to interpret the (sometimes contradictory) scientific literature. Topics of the first semester: cell membrane, muscle, blood, heart, circulation, respiration, gastrointestinal tract, metabolism, and renal functions.

Lectures

• 1. Introduction. Evidence-based medicine. How does an observation become a fact? - Ollmann Tamás
• 2. Homeostasis, theory of regulation, body fluid compartments, transport processes. The case of the toxic lady. - Ollmann Tamás
• 3. The composition of blood. Why do we need to draw blood from a patient? - Ollmann Tamás
• 4. Red blood cells and hemoglobin. From skin rash to the bone marrow. - Ollmann Tamás
• 5. White blood cells and the immune system. Possible consequences of an insect bite. - Ollmann Tamás
• 6. Blood groups. Not everything is what it seems. The challenges of blood donation. - Ollmann Tamás
• 7. Thrombocytes. Blood clotting. The patient on anticoagulant therapy and tooth extraction. - Ollmann Tamás
• 8. Basics of neurophysiology. The membrane potential. Investigating neurons. - Ollmann Tamás
• 9. Synapses. Why are ions important? - Ollmann Tamás
• 10. Molecular basis of muscle function. The significance of EMG in diagnosing diseases. - Ollmann Tamás
• 11. Muscle metabolism. Smooth muscle. The patient presenting with muscle weakness. - Ollmann Tamás
• 12. Autonomic nervous system and the basics of sensory functions. Better safe than sorry? - Ollmann Tamás
• 13. Respiration, spirometry. The case of the elderly patient who suddenly becomes short of breath in the morning while in the bathroom. - Ollmann Tamás
• 14. Regulation of breathing. The difficulties of the alpinists. - Ollmann Tamás
• 15. Heart rhythm and the ECG. The patient with suspected myocardial infarction. - Ollmann Tamás
• 16. Cardiac cycle. Regulation of cardiac function. Caries and the heart. - Ollmann Tamás
• 17. Pumping function of the heart, blood pressure, pulse. The case of the patient with heart failure. - Ollmann Tamás
• 18. Circulation. The case of the edematous patient. One symptom can have many causes… - Ollmann Tamás
• 19. Regulation of blood circulation. The case of the fainting hunter. - Ollmann Tamás
• 20. Gastrointestinal system. The case of the patient with abdominal pain. - Ollmann Tamás
• 21. Regulation of gastrointestinal function. The patient who consumes excessive alcohol. Toilet habits. The gut microbiota and the brain. - Ollmann Tamás
• 22. Healthy nutrition and various diets. Facts and misconceptions. - Ollmann Tamás
• 23. Kidney function. The difficulties of measuring renal function. - Ollmann Tamás
• 24. Urination. The mysteries of incontinence. - Ollmann Tamás

Practices

Seminars

Reading material

Obligatory literature

Literature developed by the Department

The slides will be available on Teams/PotePedia.

Notes

Recommended literature

Guyton and Hall: Textbook of Medical Physiology

Costanzo: Physiology Cases and Problems (Board Review Series)

Carroll: Problem-Based Physiology

Conditions for acceptance of the semester

attendance on 75% of the lectures, uploading the case report

Mid-term exams

Writing of case study, online test.

Making up for missed classes

Not necessary, but it is possible in another language.

Exam topics/questions

The topics of the lectures.

Examiners

Instructor / tutor of practices and seminars