Electrophysiology

Data

Official data in SubjectManager for the following academic year: 2024-2025

Topic

The interpretation of the electrical signals from patients is not merely a matter of memorizing a few characteristic pictures; there are many unusual variations and combinations of these phenomena which must be studied, analyzed, and correlated one with another and with other available data before any definite conclusion is possible. These situations demand some acquaintance with the electrical and physiologic principles by which they are determined.

The purpose of the course is to understand the origin of the electrical signals that can be recorded from excitable living tissues, the basic properties of their behavior, the main physical and physiological processes by which these signals (action potential, ECG, EEG, event related potentials, R triggered potentials, field potentials, intracellular and extracellular single unit recording) are determined. The course includes the discussion of the physical basis of electricity, resting potential, passive and active properties of the excitable membrane, voltage and ligand gated ion channels, realistic and abstract neuronal network models, the nature of the intra and extracellular signals. The origin and the physiological significance of the diagnostically important electrical signals (ECG, EEG, EMG, VEP) will also be discussed, some clinically relevant topic will also be touched.

Lectures

• 1. Electrophysics 1 - Jandó Gábor
• 2. Electrophysics 2 - Jandó Gábor
• 3. Excitable membrane 1 - Jandó Gábor
• 4. Excitable membrane 2 - Jandó Gábor
• 5. Membrane potential 1 - Jandó Gábor
• 6. Membrane potential 2 - Jandó Gábor
• 7. Action potential, field potential 1 - Jandó Gábor
• 8. Action potential, field potential 2 - Jandó Gábor
• 9. ECG basics - Jandó Gábor
• 10. ECG interpretation - Jandó Gábor
• 11. EEG evoked potential basics - Jandó Gábor
• 12. EEG interpretation - Jandó Gábor

Practices

Seminars

Reading material

Obligatory literature

Literature developed by the Department

The course material will be available on a CD. Students are freely allowed to copy the course CD.

Notes

Recommended literature

Conditions for acceptance of the semester

Acceptance: 4 absences out of 12 classes is allowed.

Mid-term exams

Exam: oral exam

Making up for missed classes

Not possible

Exam topics/questions

Students are allowed to select the most preferred topic of the course and must be prepared for the exam from that topic only. Five-ten shortly answerable questions will be asked from that topic, the mark will be established on the basis of correct answers.

Topic list:

1. Physical basis of electrophysiology, amplifiers, leads

2. Passive physiological properties of the neuron

3. Resting potential, action potential, HH model and patch-clamp technique

4. Modeling brain functions: realistic, abstract models, artificial intelligence

5. ECG basics

6. Interpretation of ECG

7. Electroencephalograpy and Event Related Potentials

8. Visual Evoked Potentials

Examiners

Instructor / tutor of practices and seminars

• Jandó Gábor