Organic Chemistry 1 - Theory

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2024-2025

Tematika

This subject is a part of chemistry basics. Its aim is to present the nomenclature, structure, physical and chemical properties, synthesis, reaction mechanisms and application of organic compounds.

Előadások

• 1. The nature of chemical bonds; Hybridization; Polar covalent bonds, electronegativity; Acids and bases: Bronsted-Lowry and Lewis definition - Kálai Tamás
• 2. The nature of chemical bonds; Hybridization; Polar covalent bonds, electronegativity; Acids and bases: Bronsted-Lowry and Lewis definition - Kálai Tamás
• 3. The nature of chemical bonds; Hybridization; Polar covalent bonds, electronegativity; Acids and bases: Bronsted-Lowry and Lewis definition - Kálai Tamás
• 4. The system of organic compounds, functional groups, reaction mechanisms. - Kálai Tamás
• 5. The system of organic compounds, functional groups, reaction mechanisms. - Kálai Tamás
• 6. Spectrometric structure identification of organic compounds. - Kálai Tamás
• 7. Isomerism and stereochemistry: constitutional isomerism, conformation, cis-trans isomerism, chirality, optical activity, specific rotation, enantiomers and diastereomers, relative and absolute configuration. - Kálai Tamás
• 8. Isomerism and stereochemistry: constitutional isomerism, conformation, cis-trans isomerism, chirality, optical activity, specific rotation, enantiomers and diastereomers, relative and absolute configuration. - Kálai Tamás
• 9. Isomerism and stereochemistry: constitutional isomerism, conformation, cis-trans isomerism, chirality, optical activity, specific rotation, enantiomers and diastereomers, relative and absolute configuration. - Kálai Tamás
• 10. Alkanes and cycloalkanes; Orbital hybridization and the structure of alkanes; Nomenclature, physical and chemical properties, conformation. - Kálai Tamás
• 11. Alkanes and cycloalkanes; Orbital hybridization and the structure of alkanes; Nomenclature, physical and chemical properties, conformation. - Kálai Tamás
• 12. Alkanes and cycloalkanes; Orbital hybridization and the structure of alkanes; Nomenclature, physical and chemical properties, conformation. - Kálai Tamás
• 13. Unsaturated hydrocarbons: sp2 and sp hybridization, nomenclature, physical properties, reactions and synthesis of alkenes and alkynes. - Kálai Tamás
• 14. Unsaturated hydrocarbons: sp2 and sp hybridization, nomenclature, physical properties, reactions and synthesis of alkenes and alkynes. - Kálai Tamás
• 15. Unsaturated hydrocarbons: sp2 and sp hybridization, nomenclature, physical properties, reactions and synthesis of alkenes and alkynes. - Kálai Tamás
• 16. Importance of unsaturated hydrocarbons in industry and biology: polymerization, isoprene, terpenes, steroids, carotenoids. - Kálai Tamás
• 17. Importance of unsaturated hydrocarbons in industry and biology: polymerization, isoprene, terpenes, steroids, carotenoids. - Kálai Tamás
• 18. Importance of unsaturated hydrocarbons in industry and biology: polymerization, isoprene, terpenes, steroids, carotenoids. - Kálai Tamás
• 19. Aromatic compounds: the structure of benzene, Hückel's rule. Electrophilic aromatic substitution reactions. Substituent effects in electrophilic aromatic substitution. Oxidation and reduction of aromatic compounds; Polycyclic compounds. - Kálai Tamás
• 20. Aromatic compounds: the structure of benzene, Hückel's rule. Electrophilic aromatic substitution reactions. Substituent effects in electrophilic aromatic substitution. Oxidation and reduction of aromatic compounds; Polycyclic compounds. - Kálai Tamás
• 21. Aromatic compounds: the structure of benzene, Hückel's rule. Electrophilic aromatic substitution reactions. Substituent effects in electrophilic aromatic substitution. Oxidation and reduction of aromatic compounds; Polycyclic compounds. - Kálai Tamás
• 22. Alkyl halides: the character of C-X bonds, synthesis and reactions of alkyl halides; Nuclephilic substitution reactions, SN1, SN2, eliminations; Organic halides in the environment. - Kálai Tamás
• 23. Alkyl halides: the character of C-X bonds, synthesis and reactions of alkyl halides; Nuclephilic substitution reactions, SN1, SN2, eliminations; Organic halides in the environment. - Kálai Tamás
• 24. Alkyl halides: the character of C-X bonds, synthesis and reactions of alkyl halides; Nuclephilic substitution reactions, SN1, SN2, eliminations; Organic halides in the environment. - Kálai Tamás
• 25. Organometallic compounds: their importance in organic syntheses (Mg, Na, Li, Zn, Si, Cu, Cd compounds). - Kálai Tamás
• 26. Organometallic compounds: their importance in organic syntheses (Mg, Na, Li, Zn, Si, Cu, Cd compounds). - Kálai Tamás
• 27. Organometallic compounds: their importance in organic syntheses (Mg, Na, Li, Zn, Si, Cu, Cd compounds). - Kálai Tamás
• 28. Alcohols: Structure, synthesis, physical and chemical properties, reactions; Their biological importance. - Pápayné Sár Cecilia
• 29. Alcohols: Structure, synthesis, physical and chemical properties, reactions; Their biological importance. - Pápayné Sár Cecilia
• 30. Alcohols: Structure, synthesis, physical and chemical properties, reactions; Their biological importance. - Pápayné Sár Cecilia
• 31. Phenols and ethers: Structure, synthesis, physical and chemical properties, reactions; Their biological importance: polyphenols. - Pápayné Sár Cecilia
• 32. Phenols and ethers: Structure, synthesis, physical and chemical properties, reactions; Their biological importance: polyphenols. - Pápayné Sár Cecilia
• 33. Phenols and ethers: Structure, synthesis, physical and chemical properties, reactions; Their biological importance: polyphenols. - Pápayné Sár Cecilia
• 34. Sulfur containing compounds: Physical, chemical properties and synthesis of thiols and sulfides; Their importance in biological processes (in amino acids, peptides, methylation in biology, AcCo-A, drugs). - Pápayné Sár Cecilia
• 35. Sulfur containing compounds: Physical, chemical properties and synthesis of thiols and sulfides; Their importance in biological processes (in amino acids, peptides, methylation in biology, AcCo-A, drugs). - Pápayné Sár Cecilia
• 36. Sulfur containing compounds: Physical, chemical properties and synthesis of thiols and sulfides; Their importance in biological processes (in amino acids, peptides, methylation in biology, AcCo-A, drugs). - Pápayné Sár Cecilia
• 37. Overview of reaction mechanisms: radical, electrophilic and nucleophilic substitutions, electrophilic additions, eliminations. - Pápayné Sár Cecilia
• 38. Overview of reaction mechanisms: radical, electrophilic and nucleophilic substitutions, electrophilic additions, eliminations. - Pápayné Sár Cecilia
• 39. Overview of reaction mechanisms: radical, electrophilic and nucleophilic substitutions, electrophilic additions, eliminations. - Pápayné Sár Cecilia
• 40. Summary - Pápayné Sár Cecilia
• 41. Summary - Pápayné Sár Cecilia
• 42. Summary - Pápayné Sár Cecilia

Gyakorlatok

Szemináriumok

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

John McMurry, Eric Simanek: Fundamentals of Organic Chemistry, 6th ed., Thomson Brooks, Belmont, 2007.

Saját oktatási anyag

The slides of the lectures are uploaded to the Neptun Meet Street.

Jegyzet

Ajánlott irodalom

T. W. Graham Solomons: Organic Chemistry, 7th edition, Wiley and Sons, New York, 2000.

William H. Brown: Organic Chemistry, Saunders College Publishing, Fort Worth, 1995.

A félév elfogadásának feltételei

Further criterion of admission to the exam is the successful completion of the practice carried out in paralell (midsemester grade with the result different from failed).

Félévközi ellenőrzések

Students write tests from the subject of the lecture on 3rd, 5th, 7th, 9th and 11th week and at least three of them must be completed better than 50 %. Those who can not complete these tests can not admit to the exam.

Távolmaradás pótlásának lehetőségei

Students have to contact the lecturer of the subject.

Vizsgakérdések

1.) Alkanes: Orbital hybridization and the structure of alkanes; Nomenclature, physical and chemical properties, combustion, free radical chlorination, conformation, cycloalkanes, type of ring strains, demonstrate with examples.

2. Unsaturated hydrocarbons: sp2 and sp hybridization, nomenclature, physical properties, reactions and synthesis of alkenes and alkynes. Electrophilic addition, Markovnikovs rule, 1,2- and 1,4-addition, conjugated and cumulated dienes.

3. Importance of unsaturated hydrocarbons in industry and biology; polymerization, isoprene, terpenes, steroids, carotenoids, polymers, rubber

4. Aromatic compounds: the structure of benzene, Hückels rule. Electrophilic aromatic substitution reactions. (Nitation, sulfonation, bromination, Friedel-Crafts reactions), direction rules, classification of substituents, polyaromatics: examples, their chemical reactions aromatic electophilic substitution, oxidation.

5. Alkyl halides: the character of C-X bonds, physical properties, reactivity of alkyl halides, synthesis of alkyl and aromatic halides, and reactions of alkyl halides (substitution, elimination); Organic halides in the environment.

6. Organometallic compounds: their structure, their importance in organic syntheses (Mg, Na, Li, Si, Cu, Cd compounds).

7. Alcohols, phenols, ethers: Structure, physical and chemical properties, reactions; Their biological importance.

8. Stereochemistry: isomerism, absolute and relative configuration, chirality, racemates, diastereomers, polarimetry, resolution.

9. Sulfur containing compounds: Physical, chemical properties, importance in biological processes (in amino acids, peptides, methylation in biology, AcCo-A, drugs, sulfonamides, penicillin, cefalosporin).

Vizsgáztatók

• Bognár Balázs
• Kálai Tamás
• Pápayné Sár Cecilia

Gyakorlatok, szemináriumok oktatói

• Bognár Balázs
• Kálai Tamás