Kutatás

Publikációs lista

• Zhang, Xiaonan ; Schalke, Berthold ; Kvell, Krisztian ; Kriegsmann, Katharina ; Kriegsmann, Mark ; Graeter, Thomas ; Preissler, Gerhard ; Ott, German ; Kurz, Katrin ; Bulut, Elena et al.: WNT4 overexpression and secretion in thymic epithelial tumors drive an autocrine loop in tumor cells in vitro. FRONTIERS IN ONCOLOGY 2022

• Kálai Tamás, Pongrácz Judit E., Mátyus Péter: Recent Advances in Influenza, HIV and SARS-CoV-2 Infection Prevention and Drug Treatment—The Need for Precision Medicine. CHEMISTRY 4 2022

• Told Roland; Ujfalusi Zoltan; Pentek Attila; Kerenyi Monika; Banfai Krisztina; Vizi Andras; Szabo Peter; Melegh Szilvia; Bovari-Biri Judit; Pongracz Judit E.; Maroti Peter: A state-of-the-art guide to the sterilization of thermoplastic polymers and resin materials used in the additive manufacturing of medical devices. MATERIALS AND DESIGN Paper 2022

• Voros-Horvath Barbara; Zivkovic Pavo; Banfai Krisztina; Bovari-Biri Judit; Pongracz Judit; Balint Gabor; Pal; Szechenyi Aleksandar: Preparation and Characterization of ACE2 Receptor Inhibitor-Loaded Chitosan Hydrogels for Nasal Formulation to Reduce the Risk of COVID-19 Viral Infection. ACS Omega 2022

• Abdelwahab ElHusseiny M M; Judit Bovari-Biri; Gabor Smuk; Janos Fillinger; Donald McPhail; Vera P Krymskaya;  Judit E Pongracz: Activated p53 in the anti-apoptotic milieu of tuberous sclerosis gene mutation induced diseases leads to cell death if thioredoxin reductase is inhibited. Apotosis 2021

• Jaromi L.; Csongei V.; Vesel M.; Abdelwahab E.M.M.; Soltani A.; Torok Z.; Smuk G.; Sarosi V.; Pongracz J.E.: Kras and egfr mutations differentially alter abc drug transporter expression in cisplatin-resistant non-small cell lung cancer. International Journal of Molecular Sciences 2021

• Abdelwahab Elhusseiny Mohamed Mahmoud; Bovari-Biri; Smuk Gabor; Harko Tunde; Fillinger Janos ; Moldvay Judit; Krymskaya Vera P; Pongracz Judit: Wnt jelátviteli kutatócsoport (PTE / SZKK)Normalization of Enzyme Expression and Activity Regulating Vitamin A Metabolism Increases RAR-Beta Expression and Reduces Cellular Migration and Proliferation in Diseases Caused by Tuberous Sclerosis Gene Mutations. Frontiers in Oncology 2021

• Csenki Zsolt; Garai Edina; Faisal Zelma; Csepregi Rita; Garai Kitti; Sipos Dóra Kánainé; Szabó István; Kőszegi Tamás; Czéh Árpád; Czömpöly Tamás; Kvell Krisztián; Poór Miklós: The individual and combined effects of ochratoxin A with citrinin and their metabolites (ochratoxin B, ochratoxin C, and dihydrocitrinone) on 2D/3D cell cultures, and zebrafish embryo models. Food and Chemical Toxcology 2021

• Soltani Amina; Kajtar Bela; Abdelwahab El Husseiny Mohamed Mahmud; Steib Anita; Horvath Zsolt; Mangel Laszlo; Jaromi Luca; Pongracz Judit E.:  Is an Immunosuppressive Microenvironment a Characteristic of Both Intra- and Extraparenchymal Central Nervous Tumors? Pathophysiology 2021

• Garai Kitti; Adam Zoltan  Robert Herczeg; Krisztina Banfai;  Adam Gyebrovszki;  Attila Gyenesei; Judit E Pongracz; Marta Wilhelm; Krisztian Kvell: Physical Activity as a Preventive Lifestyle Intervention Acts Through Specific Exosomal miRNA Species-Evidence From Human Short- and Long-Term Pilot Studies. Frontiers in Physiology 2021

• Weich Alexander; Rogoll Dorothee; Gawlas Sophia; Mayer Lars; Weich Wolfgang; Pongracz Judit; Kudlich Theodor; Meining Alexander; Scheurlen Michael: Wnt/β-Catenin Signaling Regulates CXCR4 Expression and [68Ga] Pentixafor Internalization in Neuroendocrine Tumor Cells. Diagnostics 2021

• Kiss Edit; Abdelwahab, El Husseiny Mohamed Mahmud; Steib Anita; Papp Emoke; Torok Zsofia; Jakab Laszlo; Smuk Gabor; Sarosi Veronika; Pongracz Judit Erzsebet:  Cisplatin treatment induced interleukin 6 and 8 production alters lung adenocarcinoma cell migration in an oncogenic mutation dependent manner. Respiratory Research 2020

• Papp Emoke; Steib Anita; Abdelwahab, Elhusseiny MM; Meggyes-Rapp Judit; Jakab Laszlo; Smuk Gabor; Schlegl Erzsebet; Moldvay Judit; Sárosi Veronika; Pongracz Judit E.: Feasibility study of in vitro drug sensitivity assay of advanced non-small cell lung adenocarcinomas. Respiratory Research 2020

• Boda Francisc; Banfai Krisztina; Garai Kitti; Kovacs Bela; Almasi Attila; Scheffer Dalma; Sinkler Reka; Csonka Robert; Czompoly Tamas; Kvell Krisztian: Effect of Bitis gabonica and Dendroaspis angusticeps snake venoms on apoptosis-related genes in human thymic epithelial cells. Journal of Venomous Animals and Toxins Iincluding Tropical Diseases 2020

• Papp Henrietta; Zeghbib Safia; Földes Fanni; Banfai Krisztina; Madai Mónika; Kemenesi Gábor; Urbán Péter; Kvell Krisztián; Jakab, Ferenc: Crimean-Congo hemorrhagic fever virus infection triggers the upregulation of the Wnt signaling pathway inhibitor genes. Virus Genes 2020

• Kovacs Noemi-Piroska; Attila Almási; Garai Kitti; Kuzma Mónika; Vancea Szende; Fischer Emil; Perjesi Pal:  Investigation of intestinal elimination and biliary excretion of ibuprofen in control and hyperglycemic rats. Canadian Journal of Physiology and Pharmacology 2019.

• Mangel László; Najbauer József; Kajtár Béla; Pongrácz Erzsébet Judit: A gliómák immunterápiájának nehézségei és reményei. Magyar Onkológia 2019

• Elhusseiny Mohamed Mahmud Abdelwahab, Judit Rapp, Diana Feller, Veronika Csongei, Szilard Pal, Domokos Bartis, David R Thickett, Judit Erzsebet Pongracz: Wnt signaling regulates trans-differentiation of stem cell like Type 2 alveolar epithelial cells to Type 1 epithelial cells. Respiratory Research 2019

• Garai, K., Adam, Z., Herczeg, R, Katai, E., Nagy, T., Pal, S., Gyenesei, A., Pongracz, JE., Wilhelm, M., Kvell, K.: Artificial neural network correlation and biostatistics evaluation of physiological and molecular parameters in healthy young individuals performing regular exercise. Frontiers in Physiology 2019 

• Vas V, Háhner T, Kudlik G, Ernszt D, Kvell K, Kuti D, Kovács KJ, Tóvári J, Trexler M, Merő BL, Szeder B, Koprivanacz K, Buday L. Analysis of Tks4 Knockout Mice Suggests a Role for Tks4 in Adipose Tissue Homeostasis in the Context of Beigeing. Cells 2019 

• Banfai K, Garai K, Ernszt D, Pongracz JE, Kvell K. Transgenic Exosomes for Thymus Regeneration. Frontiers in Immunology 2019 

• Banfai K, Ernszt D, Pap A, Bai P, Garai K, Belharazem D, Pongracz JE, Kvell K. ‚Beige‘ Cross Talk between the Immune System and Metabolism. Frontiers in Endocrinology 2019 

• Abdelwahab EMM, Pal S, Kvell K, Sarosi V, Bai P, Rue R, Krymskaya V, McPhail D, Porter A, Pongracz JE.: Mitochondrial dysfunction is a key determinant of the rare disease lymphangioleiomyomatosis and provides a novel therapeutic target.Oncogene 2019 

• Feller D, Kun J, Ruzsics I, Rapp J, Sarosi V, Kvell K, Helyes Z, Pongracz JE.: Cigarette Smoke-Induced Pulmonary Inflammation Becomes Systemic by Circulating Extracellular Vesicles Containing Wnt5a and Inflammatory Cytokines. Frontiers in Immunology 2018 

• Boda F, Banfai K, Garai K, Curticapean A, Berta L, Sipos E, Kvell K.: Effect of Vipera ammodytes ammodytes Snake Venom on the Human Cytokine Network. Toxins 2018 

• Ernszt D, Banfai K, Kellermayer Z, Pap A4 Lord JM, Pongracz JE, Kvell K.PPARgamma Deficiency Counteracts Thymic Senescence. Frontiers in Immunology 2017 

• Pénzes Á, Mahmud Abdelwahab EM, Rapp J, Péteri ZA, Bovári-Biri J, Fekete C, Miskei G, Kvell K, Pongrácz JE. Toxicology studies of primycin-sulphate using a three-dimensional (3D) in vitro human liver aggregate model. Toxicology Letters 2017 

• Rapp J, Jaromi L, Kvell K, Miskei G, Pongracz JE. WNT signaling - lung cancer is no exception. Respiratory Research 2017 

• Vesel M., Rapp J., Feller, D., Kiss, E., Jaromi, L., Meggyes, M, Miskei, G., Duga, B., Smuk, G., Laszlo, T., Karner, I., Pongracz, J.E.: ABCB1 and ABCG2 drug transporters are differentially expressed in non-small cell lung cancers (NSCLC) and expression is modified by cisplatin treatment via altered Wnt signaling. Respiratory Research 2017

• Rapp J, Kiss E, Meggyes M, Szabo-Meleg E, Feller D, Smuk G, Laszlo T, Sarosi V, Molnar TF, Kvell K, Pongracz JE. Increased Wnt5a in squamous cell lung carcinoma inhibits endothelial cell motility. BMC Cancer 2016 

• Dülk M, Kudlik G, Fekete A, Ernszt D, Kvell K, Pongrácz JE, Merő BL, Szeder B, Radnai L, Geiszt M, Csécsy DE, Kovács T, Uher F, Lányi Á, Vas V, Buday L. The scaffold protein Tks4 is required for the differentiation of mesenchymal stromal cells (MSCs) into adipogenic and osteogenic lineages. Scietific Reports 2016 

• Bartis D, Crowley LE, D'Souza VK, Borthwick L, Fisher AJ, Croft AP, Pongrácz Thompson R, Langman G, Buckley CD, Thickett DR. Role of CD248 as a potential severity marker in idiopathic pulmonary fibrosis. BMC Pulmonary Medicine 2016 
• Kovacs T, Csongei V, Feller D, Ernszt D, Smuk G, Sarosi V, Jakab L, Kvell K, Bartis D, Pongracz JE. Alteration in the Wnt microenvironment directly regulates molecular events leading to pulmonary senescence. Aging Cell 2014 
• Kvell K, Fejes AV, Parnell SM, Pongracz JE. Active Wnt/beta-catenin signaling is required for embryonic thymic epithelial development and functionality ex vivo. Immunobiology 2014 
• Bartis D, Csongei V, Weich A, Kiss E, Barko S, Kovacs T, Avdicevic M, D'Souza VK, Rapp J, Kvell K, Jakab L, Nyitrai M, Molnar TF, Thickett DR, Laszlo T,Pongracz JE. Down-regulation of canonical and up-regulation of non-canonical Wnt signalling in the carcinogenic process of squamous cell lung carcinoma. PLoS One 2013