The Cytoskeletal System

Daten

Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2024-2025

Thematik

The cytoskeleton built of different protein networks has versatile structural and functional features essential for almost all cellular processes. The dysfunctioning of the cytoskeleton can often result in pathological alterations of cellular functions leading to diseases. The first module of the course introduces the components and properties of the cytoskeletal protein networks. The second module specializes in case studies on the pathological alterations of the cytoskeleton and the underlying diseases. Experimental techniques used to examine the cytoskeleton are presented during interactive classes and laboratory sessions. The course can contribute to a better understanding of the biological, physical, and chemical principles underlying cellular functioning, as well as corresponding topics of compulsory subjects (e.g. molecular cell biology).

Module 1 – introduction: Components and functions of the cytoskeleton.

Module 2 – case studies: Pathological alterations and diseases related to the cytoskeleton.

Module 3 – interactive sessions: Cell biological, biophysical and biochemical approaches in the investigation of the cytoskeleton.

Vorlesungen

• 1.

  Properties and biological functions of cytoskeletal polymers.

  - Bugyi Beáta
• 2.

  Properties and biological functions of cytoskeletal polymers.

  - Bugyi Beáta
• 3.

  Case study 1: cytoskeletal polymers as potential therapeutic targets.

  - Gaszler Péter
• 4.

  Case study 2: carcinogenesis.

  - Gaszler Péter
• 5.

  Case study 3: pathogens.

  - Szütsné Tóth Mónika Ágnes
• 6.

  Case study 4: myopathies.

  - Szütsné Tóth Mónika Ágnes
• 7.

  Lab techniques in the investigation of the cytoskeleton, laboratory visit 1.

  - Bugyi Beáta
• 8.

  Lab techniques in the investigation of the cytoskeleton, laboratory visit 2.

  - Bugyi Beáta
• 9.

  Lab techniques in the investigation of the cytoskeleton, laboratory visit 3.

  - Leipoldné Vig Andrea Teréz
• 10.

  Lab techniques in the investigation of the cytoskeleton, laboratory visit 4.

  - Leipoldné Vig Andrea Teréz
• 11. Workshop. Students' projects and presentations. - Bugyi Beáta
• 12. Workshop. Students' projects and presentations. - Bugyi Beáta

Praktika

Seminare

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Vom Institut veröffentlichter Lehrstoff

Can be found on MS Teams group of the course.

Skript

Empfohlene Literatur

Jonathon Howard: Mechanics of Motor Proteins and the Cytoskeleton, 2005

S. Trachtenberg: The Prokaryotic Cytoskeleton: A Written Symposium, Journal of Molecular Microbiology and Biotechnology, 2006

Leslie P. Gartner, James L. Hiatt (eds.): Color Textbook of Histology 3, illustrated, revised, Saunders/Elsevier, 2007

Online materials on departmental website (http://biofizika.aok.pte.hu)

Voraussetzung zum Absolvieren des Semesters

Maximum of 25% absence allowed.

Semesteranforderungen

Grading policy

The grade is based on the result of

a written test,

or short (5-10 minutes) presentations of Students’ projects or laboratory notebooks.

Möglichkeiten zur Nachholung der Fehlzeiten

The opportunity to make up for absence can be discussed with the course leader.

Prüfungsfragen

No exam in the exam period.

Prüfer

Praktika, Seminarleiter/innen