Daten
Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2020-2021
Lehrbeauftragte/r
-
Tibor Attila RAUCH
senior research fellow,
Department of Medical Biology and Central Electron Microscope Laboratory -
Semesterwochenstunden
Vorlesungen: 12
Praktika: 0
Seminare: 0
Insgesamt: 12
Fachangaben
- Kode des Kurses: OSF-MLP-T
- 1 kredit
- Dentistry
- Optional modul
- autumn
keine
Zahl der Kursteilnehmer für den Kurs:
min. 1 – max. 50
Erreichbar als Campus-Kurs für 1 fő számára. Campus-karok: ÁOK TTK
Thematik
Why are certain family members affected by tumorous diseases and others are not? Can the lifestyles of our grandparents and parents affect our health? What kind of molecular factors and mechanisms might be involved in epigenetics, including transgenerational inheritance? Is epigenetics the missing link between genetics, the environment and disease? These fundamental questions will be addressed and the latest advances of the field will be discussed. Moreover, epigenetic biomarkers and therapeutic potential of epigenetic drugs (epigenetic enzyme inhibitors) will be also covered.
Vorlesungen
- 1. Milestones of epigenetics - from Conrad Waddington to David Allis - Dr. Rauch Tibor Attila
- 2. DNA methylation and demethylation – the first discovered epigenetic alterations - Dr. Rauch Tibor Attila
- 3. Histone protein-related epigenetic signals - Dr. Rauch Tibor Attila
- 4. Non-coding RNAs (miRNA, piRNA and lncRNA) in cell biology and pathogeneses - Dr. Rauch Tibor Attila
- 5. Epigenetic methods, including single-locus and genome-wide analysis tools - Dr. Rauch Tibor Attila
- 6. Genetic imprinting and X chromosome inactivation - Dr. Rauch Tibor Attila
- 7. Stem cell and differentiation-associated epigenetic events - Dr. Rauch Tibor Attila
- 8. Epigenetics of cancer - Dr. Rauch Tibor Attila
- 9. Epigenetics of autoimmune diseases - Dr. Rauch Tibor Attila
- 10. Epigenetic aspects of memory and neurological disorders - Dr. Rauch Tibor Attila
- 11. Epigenetic biomarkers and therapeutic interventions - Dr. Rauch Tibor Attila
- 12. Exam (oral or written) - Dr. Rauch Tibor Attila
Praktika
Seminare
Materialien zum Aneignen des Lehrstoffes
Obligatorische Literatur
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Vom Institut veröffentlichter Lehrstoff
PowerPoint presentation according to lectures
Skript
-
Empfohlene Literatur
Handbook of Epigenetics, 2nd Edition, Editors: Trygve Tollefsbol, eBook ISBN: 9780128054772, Hardcover ISBN: 9780128053881, Academic Press, Published Date: 7th August 2017
Voraussetzung zum Absolvieren des Semesters
Maximum of 15 % absence allowed
Semesteranforderungen
Closing test
Möglichkeiten zur Nachholung der Fehlzeiten
None
Prüfungsfragen
1. Milestones of epigenetics
2. DNA methylation and demethylation
3. Histone protein-related epigenetic signals
4. Non-coding RNAs
5. Epigenetic methods
6. Genetic imprinting
7. Stem cell and differentiation-associated epigenetic events
8. Epigenetics of cancer
9. Epigenetics of autoimmune diseases
10. Epigenetic aspects of memory and neurological disorders
11. Epigenetic biomarkers and therapeutic interventions
12. X-chromosome inactivation