Genetic Background of Gene Manipulation II

Daten

Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2023-2024

Thematik

The subject expands on the knowledge which was accumulated in the previous semester. Gene mutation, DNA repair mechanisms and transposition, regulation of gene expression, transcriptional and post-transcriptional regulation will be discussed. Finally, epigenetic regulation of gene expression and its consequences will be the final topic.

Vorlesungen

• 1. Gene mutations - Dr. Pongrácz Judit Erzsébet
• 2. Replication errors and Base modifications - Dr. Pongrácz Judit Erzsébet
• 3. Induced mutations induced by chemicals and radiation I. - Dr. Pongrácz Judit Erzsébet
• 4. Induced mutations induced by chemicals and radiation II. - Dr. Pongrácz Judit Erzsébet
• 5. Mutations in the background of human diseases I. - Dr. Pongrácz Judit Erzsébet
• 6. Mutations in the background of human diseases II. - Dr. Pongrácz Judit Erzsébet
• 7. Transposable elements - Dr. Pongrácz Judit Erzsébet
• 8. Regulation of gene expression in bacteria - Dr. Pongrácz Judit Erzsébet
• 9. Regulation of gene expression in Eukaryotes - Dr. Pongrácz Judit Erzsébet
• 10. Transcriptional regulation in Eukaryotes - Dr. Pongrácz Judit Erzsébet
• 11. The epigenome - Dr. Pongrácz Judit Erzsébet
• 12. Regulation of the epigenome - Dr. Pongrácz Judit Erzsébet
• 13. Epigenetics and diseases - Dr. Pongrácz Judit Erzsébet
• 14. Epigenetic traits - Dr. Pongrácz Judit Erzsébet

Praktika

• 1. Sequence alignments
• 2. Sequence alignments
• 3. Sequence alignments
• 4. Sequence alignments
• 5. The effect of UV irradiation on cellular morphology and function
• 6. The effect of UV irradiation on cellular morphology and function
• 7. The effect of UV irradiation on cellular morphology and function
• 8. The effect of UV irradiation on cellular morphology and function
• 9. The effect of UV irradiation on gene expression
• 10. The effect of UV irradiation on gene expression
• 11. The effect of UV irradiation on gene expression
• 12. The effect of UV irradiation on gene expression
• 13. BLASTS - bioinformatics
• 14. BLASTS - bioinformatics
• 15. BLASTS - bioinformatics
• 16. BLASTS - bioinformatics
• 17. Designing disease models - Chromosomal modification - Downsyndrome mouse model
• 18. Designing disease models - Chromosomal modification - Downsyndrome mouse model
• 19. Designing disease models - Chromosomal modification - Downsyndrome mouse model
• 20. Designing disease models - Chromosomal modification - Downsyndrome mouse model
• 21. Designing disease models - transposons
• 22. Designing disease models - transposons
• 23. Designing disease models - transposons
• 24. Designing disease models - transposons
• 25. Swiss prot - protein sequences in disease analysis
• 26. Swiss prot - protein sequences in disease analysis
• 27. Swiss prot - protein sequences in disease analysis
• 28. Swiss prot - protein sequences in disease analysis

Seminare

• 1. Replication errors and Base modifications
• 2. Replication errors and Base modifications
• 3. Induced mutations induced by chemicals
• 4. Induced mutations induced by radiation
• 5. Mutations in the background of human diseases case study I.
• 6. Mutations in the background of human diseases case study II.
• 7. Mutations in the background of human diseases case study III.
• 8. Comparison of gene expression regulation in bacteria and humans I.
• 9. Comparison of gene expression regulation in bacteria and humans II.
• 10. Comparison of gene expression regulation in bacteria and humans III.
• 11. Comparison of gene expression regulation in bacteria and humans IV.
• 12. Epigenetics in the background of human diseases case study I.
• 13. Epigenetics in the background of human diseases case study II.
• 14. Epigenetics in the background of human diseases case study III.

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Vom Institut veröffentlichter Lehrstoff

Own ppt, interactive teaching material

Skript

Empfohlene Literatur

Klug et al: Concepts of Genetics 12th Edition
Pierce: Genetics - A Conceptual Approach 7th Edition (2020)

Voraussetzung zum Absolvieren des Semesters

Maximum of 15 % absence allowed

Semesteranforderungen

One midterm test, that can be repeated two more times if necessary.

Möglichkeiten zur Nachholung der Fehlzeiten

None

Prüfungsfragen

Teams, Neptun, Departmental website

Prüfer

• Dr. Pongrácz Judit Erzsébet
• Garai Kitti

Praktika, Seminarleiter/innen

• Ádám Zoltán Mihály
• Garai Kitti