Data
Official data in SubjectManager for the following academic year: 2025-2026
Course director
-
Engelmann Péter András
associate professor,
Department of Immunology and Biotechnology -
Number of hours/semester
lectures: 0 hours
practices: 0 hours
seminars: 12 hours
total of: 12 hours
Subject data
- Code of subject: OXF-EVO-h-T
- 1 kredit
- Allgemeine Humanmedizin
- Optional modul
- autumn
ODA-IMM-T finished , ODA-MB2-T finished
Course headcount limitations
min. 5 – max. 30
Topic
The course describes the molecular and cellular elements of innate/adaptive immunity in their evolutionary contexts. Moreover, it discusses the ancient immune functions (phagocytosis, antimicrobial molecules, antiviral RNA interference) along with the newest research data about the development of adaptive immunity.
Lectures
Practices
Seminars
- 1. Definition of the topics and course, comparison of innate and adaptive immunity - Engelmann Péter András
- 2. Pattern recognition receptors: Toll, Croquemort and others - Engelmann Péter András
- 3. Conserved signal transduction pathways in immunology - Engelmann Péter András
- 4. Cellular immune functions of innate immunity: phagocytosis, cytotoxicity, encapsulation-, capsule-, granulomeformation - Engelmann Péter András
- 5. Humoral immune components I: antimicrobial molecules, peptides. Prophenoloxidase cascade, coagulation. - Engelmann Péter András
- 6. Humoral immune components II: Acute-phase proteins, complement-evolution - Engelmann Péter András
- 7. Humoral immune components III: evolution of cytokines and chemokines - Engelmann Péter András
- 8. Sounds of Silence or the role of RNA interference (RNAi) in innate immunity, antiviral innate immunity - Engelmann Péter András
- 9. Alternative adaptive immunity in invertebrates and in ancient vertebrates? - Engelmann Péter András
- 10. Histoincompatibility in invertebrates, MHC-evolution - Engelmann Péter András
- 11. Immunological twilight-zone - The appearance of adaptive immunity, Immunological triumvirate: RAG-time: immunglobulin, TCR development in the context of phylogenesis - Engelmann Péter András
- 12. Phylogenetical development of vertebrate immune organs, host-pathogen co-evolution - Engelmann Péter András
Reading material
Obligatory literature
Literature developed by the Department
www.immbio.hu
Notes
Recommended literature
http://www.sciencedirect.com/science/journal/0145305X
Conditions for acceptance of the semester
Referral, max. 2 absences from the seminars
Mid-term exams
Presentation
Making up for missed classes
Individual preparation
Exam topics/questions
-
Examiners
Instructor / tutor of practices and seminars
- Engelmann Péter András