Evolutionary Immunobiology

Daten

Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2025-2026

Lehrbeauftragte/r

  • Engelmann Péter András

    associate professor,
    Department of Immunology and Biotechnology

Semesterwochenstunden

Vorlesungen: 0

Praktika: 0

Seminare: 12

Insgesamt: 12

Fachangaben

  • Kode des Kurses: OXF-EVO-h-T
  • 1 kredit
  • Allgemeine Humanmedizin
  • Optional modul
  • autumn
Voraussetzungen:

ODA-IMM-T finished , ODA-MB2-T finished

Zahl der Kursteilnehmer für den Kurs:

min. 5 – max. 30

Thematik

The course describes the molecular and cellular elements of innate/adaptive immunity in their evolutionary contexts. Moreover, it discusses the ancient immune functions (phagocytosis, antimicrobial molecules, antiviral RNA interference) along with the newest research data about the development of adaptive immunity.

Vorlesungen

Praktika

Seminare

  • 1. Definition of the topics and course, comparison of innate and adaptive immunity - Engelmann Péter András
  • 2. Pattern recognition receptors: Toll, Croquemort and others - Engelmann Péter András
  • 3. Conserved signal transduction pathways in immunology - Engelmann Péter András
  • 4. Cellular immune functions of innate immunity: phagocytosis, cytotoxicity, encapsulation-, capsule-, granulomeformation - Engelmann Péter András
  • 5. Humoral immune components I: antimicrobial molecules, peptides. Prophenoloxidase cascade, coagulation. - Engelmann Péter András
  • 6. Humoral immune components II: Acute-phase proteins, complement-evolution - Engelmann Péter András
  • 7. Humoral immune components III: evolution of cytokines and chemokines - Engelmann Péter András
  • 8. Sounds of Silence or the role of RNA interference (RNAi) in innate immunity, antiviral innate immunity - Engelmann Péter András
  • 9. Alternative adaptive immunity in invertebrates and in ancient vertebrates? - Engelmann Péter András
  • 10. Histoincompatibility in invertebrates, MHC-evolution - Engelmann Péter András
  • 11. Immunological twilight-zone - The appearance of adaptive immunity, Immunological triumvirate: RAG-time: immunglobulin, TCR development in the context of phylogenesis - Engelmann Péter András
  • 12. Phylogenetical development of vertebrate immune organs, host-pathogen co-evolution - Engelmann Péter András

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Vom Institut veröffentlichter Lehrstoff

www.immbio.hu

Skript

Empfohlene Literatur

http://www.sciencedirect.com/science/journal/0145305X

Voraussetzung zum Absolvieren des Semesters

Referral, max. 2 absences from the seminars

Semesteranforderungen

Presentation

Möglichkeiten zur Nachholung der Fehlzeiten

Individual preparation

Prüfungsfragen

-

Prüfer

Praktika, Seminarleiter/innen

  • Engelmann Péter András