Pathophysiology of Chronic Obstructive Lung Diseases (COPD)

Data

Official data in SubjectManager for the following academic year: 2024-2025

Course director

Number of hours/semester

lectures: 12 hours

practices: 0 hours

seminars: 0 hours

total of: 12 hours

Subject data

  • Code of subject: OAE-COP-T
  • 1 kredit
  • General Medicine
  • Elective modul
  • autumn
Prerequisites:

OAA-OBK-T finished , OAA-EL2-T finished , OAP-KN1-T parallel

Course headcount limitations

min. 5 – max. 100

Topic

Chronic obstructive lung diseases (COPD) are among the leading causes of mortality in our society. The aim of the course is to analyse the epidemiology, pathogenesis and consequences of the diseases that belong to COPD with regard to the latest scientific evidence. Topics of the course include the pathophysiology of smoking and its consequences, the theoretical basis of the prevention and therapy of bronchial asthma, chronic bronchitis and emphysema. Participants of the course will take an active part in lung function tests in the Laboratory of Respiratory Physiology and gain practical insight in the functional diagnostics of COPD. Theory will be complemented by case histories.

Lectures

  • 1. Definition of chronic obstructive pulmonary diseases._x000D_ Epidemiology of COPD. Systemic inflammation in COPD. - Balaskó Márta
  • 2. Pathophysiological consequences of smoking/tobacco use. - Balaskó Márta
  • 3. Case history. Chronic bronchitis: etiology, pathogenesis, and complications. I - Balaskó Márta
  • 4. Chronic bronchitis: etiology, pathogenesis, and complications. II - Balaskó Márta
  • 5. Emphysema: etiology, pathogenesis, and complications I - Balaskó Márta
  • 6. Emphysema: etiology, pathogenesis, and complications II. Case history. - Balaskó Márta
  • 7. Established drugs in the therapy of COPD. - Balaskó Márta
  • 8. New directions in the therapy of COPD. Differential diagnosis of COPD. - Balaskó Márta
  • 9. Etiology and pathogenesis of bronchial asthma I - Balaskó Márta
  • 10. Etiology and pathogenesis of bronchial asthma II. Case history. - Balaskó Márta
  • 11. Pathophysiological concepts of asthma treatment. I - Balaskó Márta
  • 12. Pathophysiological concepts of asthma treatment II. New directions of drug development. Case history. - Balaskó Márta

Practices

Seminars

Reading material

Obligatory literature

Literature developed by the Department

Lecture slides are uploaded to TEAMS.

Notes

Recommended literature

Harrison: The Principles of Internal Medicine, 16th edition, (respective chapters), McGraw-Hill 2005 ISBN 0071391428

Székely Miklós (editor) Basic concepts in pathopysiology. Medicina Publishing House Budapest, 2019.

Conditions for acceptance of the semester

None

Mid-term exams

None.

Making up for missed classes

An essay on the topic of the missed lecture.

Exam topics/questions

The definition and epidemiological features of COPD

Etiology and pathogenesis of chronic bronchitis

Lung function tests and other diagnostic criteria of chronic bronchitis

Complications of chronic bronchitis

Pathophysiological basis of the treatment of chronic bronchitis

Etiology, pathogenesis and complications of emphysema

The pathophysiology of smoking

The definition and epidemiological features of bronchial asthma

Etiology and pathogenesis of bronchial asthma

Lung function tests and other diagnostic criteria of bronchial asthma

Complications of bronchial asthma

Pathophysiological concept of the treatment of bronchial asthma

The grade depends on the final test score.

Examiners

Instructor / tutor of practices and seminars