Student Researchers' Society Topics

The perianalis fistula is the chronic form of the perianal inflammations. The acut form is the perianal abscess, the fistula can develope after this. The treatment is really difficult. The cause of this is mostly the localization, it is irritated and contaminated every day by the stool and the stool in the tract maintains the inflammation. There are more surgical therapeutical options, but none of them is really good. Expectedly the adaptation of the more and more popular NPWT we will reach a much better cure.

Due to the agressiveness and delayed recognition of pancreatic cancer the researches came to the front to solve these problems. By the development of screening methods – which promote the early diagnosis – therapy of the patients would be carried out in time in an earlier stage. Thus the prognosis and the survival of the patients would improve. One of these new possibilities is the calorimetric examination of serum, which has promising first results.

The mesh repair of an abdominal wall hernia provides significantly lower recurrence rate, but the biological behavior of the abdominal wall is irreversibly changed. The long term results of mesh implantation are still unknown. The goal of this topic is to measure the biomechanical changes after mesh repair (in vitro) and compare these results retrospectively to non-mesh reconstructions (in vivo).

the goal of this retrospective clinical investigation is that the long term result of the surgical total mesorectal excision can be equal to neoadjuvant radiotherapy among T2-T3 rectal cancer.

It is the highest importance to determine the preoperative state of a patient waiting for lung resection. There are plenty of static and dynamic stress tests to evaluate a patients clinical state, but there is the need to assess the parameters and have a complete cardio-respiratory evaluation. We are investigating and evaluating the differet preoperative stress test in the clinical setting.

Though the operative mortality rate is under 5% in specialized centres, the morbidity rate is still high (30-50%) after pancreatoduodenectomies. There have been great efforts to decrease these complications, like pancreatic fistula, delayed gastric emptying, bleeding, etc., without significant improvement. The aim of the topic is to detail the literature background, and also to show the own results of the Department of Surgery, University of Pécs. The technical innovations, developed by the mentor, have to be demonstrated, too. 

The proctological diseases causes – hemorrhoids, fissure, rectocele, anal prolapse, stool incontinence – severe challenge for the surgeon and requires many uncomfortable or painful instrumental examinations. The effective treatment of these diseases requires experience and advanced functional approach. Many modern diagnostic and therapeutic procedures were brought to live in the last decade. Compare of new and standard techniques can confirm or degrade the use of new methods.

Over the last 30 years, the benefits of surgical resection for liver metastases have been established. Actually, surgical resections are feasible with a very low mortality and a 5-year survival that approaches 40 %. But surgery is feasible in only 10 % to 20 % of the patients. Recent progresses in the field of chemotherapy and the development of ablative techniques increases the number of patients that could be operated with a curative intent. During this work we have to analyses our patients’ data who were underwent liver resections for metastasis, and we have to identify factors, which can predict the survival.

The number of organs removed for transplantation is far behind the demand, which is constantly growing. According to the experience coming from western societies this situation is significantly improved by the donation of organs by living donors. In Hungary, the Department of Surgery of University Pécs played an important role in the introduction of hand assisted laparoscopic donor nephrectomy.  The retrospective analysis and publication of characteristics of donors and recipients, which are significantly beyond the average, could help to enhance the number of healthy donor volunteers.

Opposite to many Hungarian surgical departments in our clinic the laparoscopic approach of appendectomy is routinely performed. Great numbers of papers allude to the clinical advantage of laparoscopic appendectomy. Retrospective clinical investigation is requisite to compare the short and long term results (related infectious disease and related quality of life) of appendectomies.

Co-supervisor: Prof. Dr. REGLŐDI, Dóra

Pancreatic cancers are becoming more common worldwide and survival is still very low. The exact causes and background of tumor development and progression are not yet fully elucidated, although this could promise effective treatment options. Knowledge of the neurophysiological background seems essential for this. We analyze the expression of one such neuromodulatory peptide, pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors in human tissue samples. We also plan to analyze the effect of PACAP on tumor growth in cell cultures.

Minimal access surgery plays a growing role in thoracic surgery. We investigate the the diagnostic methods and surgical techniques as well as pathologic and molecular biological analysis of VATS technique.

In the last decades a great progress can be observed in pancreatic surgery, like vascular resections, artery first approach, uncinate process first dissection, multivisceral procedures, neoadjuvant therapy for locally advanced tumours, modifications of pancreatic anastomosis, etc. The aim is to investigate these tendencies in the practice of the Department of Surgery, Clinical Center, University of Pécs. 

The severe form of acute pancreatitis associates with high mortality rate even nowadays. The exact patomechanism has not been cleared up yet, thus there is no specific therapy. This is a multidisciplinary task.  The expected prognosis may be determined quite early by the clinical picture and the prognostic signs. Proper therapy is needed for the chance of surviving. Recently the role of surgery has been displaced and the treatment strategy was also changed, moreover several minimal invasive methods may be applied.

the appearance of surgical site infection (SSI) causes severe challenge for the surgeon. There are many theories to prevent SSI, but none of these were absolutely confirmed. Data show that the preoperatively-given extra protein diet could decrease the presence of SSI more than the antibioticum prophylaxis. Clinical investigation is needed for turning the scale.

In case of chronic pancreatitis the pain existing despite conservative treatment is the most common indication for surgery. In additon compression syndrom (stenosis of common bile duct and/or duodenum) pseudocyst and pseudoaneurysm fomation can constitute an indication for surgery. The aim of the study is the examination of funtional results, the comparison of preoperative and postoperative complaints, the quality of life measurement after an organ-preserving surgery (duodenal preserving resection of the pancreatic head according to Frey, and the Bern modification) performed due to chronic pancreatitis.