Pharmaceutical Chemistry 3 - Theory

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2019-2020

Tematika

Introduction to molecular aspect, structure-activity relationship and pharmacopoeal qualification of selected group of active pharmaceutical ingredients. Basic principles and application of the analytical methods most frequently used in the pharmacopoeal qualifications.

Előadások

• 1. Application of CD and ORD spectroscopy in pharmaceutical analysis. - Dr. Perjési Pál
• 2. Application of UV-Vis spectroscopy in pharmaceutical analysis. - Dr. Perjési Pál
• 3. Application of UV-Vis spectroscopy in pharmaceutical analysis. - Dr. Perjési Pál
• 4. Application of thermoanalytic methods in pharmaceutical analysis. - Dr. Kulcsár Győző Kornél
• 5. Application of fluorimetry in pharmaceutical analysis. - Dr. Perjési Pál
• 6. Application of fluorimetry in pharmaceutical analysis. - Dr. Perjési Pál
• 7. Application of atomic absorption spectrometry and flame photometry in pharmaceutical analysis. - Dr. Kulcsár Győző Kornél
• 8. Application of IR spectroscopy in pharmaceutical analysis. - Dr. Lóránd Tamás
• 9. Application of IR spectroscopy in pharmaceutical analysis. - Dr. Lóránd Tamás
• 10. Biological drugs I. - Dr. Rozmer Zsuzsanna
• 11. Application of NMR spectroscopy in pharmaceutical analysis. - Dr. Perjési Pál
• 12. Application of NMR spectroscopy in pharmaceutical analysis. - Dr. Perjési Pál
• 13. Biological drugs II. - Dr. Rozmer Zsuzsanna
• 14. Application of mass spectrometry in pharmaceutical analysis. - Dr. Kulcsár Győző Kornél
• 15. Application of mass spectrometry in pharmaceutical analysis. - Dr. Kulcsár Győző Kornél
• 16. Antiallergic antihistamines. Drugs for rheumatic gout I. - Dr. Rozmer Zsuzsanna
• 17. Application of electroanalytical methods in pharmaceutical analysis. - Dr. Perjési Pál
• 18. Application of electroanalytical methods in pharmaceutical analysis. - Dr. Perjési Pál
• 19. Antiallegic antihistamines. Drugs for rheumatic gout II. - Dr. Rozmer Zsuzsanna
• 20. Agents of cardiac failure. - Dr. Huber Imre
• 21. Agents of cardiac failure. - Dr. Huber Imre
• 22. Antianginal drugs. - Dr. Rozmer Zsuzsanna
• 23. Agents of antiarythmic agents. - Dr. Huber Imre
• 24. Agents of antiarythmic agents. - Dr. Huber Imre
• 25. Antithrombotics, Thrombolytics, Coagulants I. - Dr. Rozmer Zsuzsanna
• 26. Antihipertensive agents. - Dr. Almási Attila
• 27. Antihipertensive agents. - Dr. Almási Attila
• 28. Antithrombotics, Thrombolytics, Coagulants II. - Dr. Rozmer Zsuzsanna
• 29. Antihiperlidemic agents. - Dr. Almási Attila
• 30. Antihiperlidemic agents. - Dr. Almási Attila
• 31. Drugs affecting thyroid functions. - Dr. Almási Attila
• 32. Diuretics. - Dr. Almási Attila
• 33. Diuretics. - Dr. Almási Attila
• 34. Adrenocorticoids I. - Dr. Perjési Pál
• 35. Drugs affecting calcium homeostatis. - Dr. Rozmer Zsuzsanna
• 36. Drugs affecting calcium homeostatis. - Dr. Rozmer Zsuzsanna
• 37. Adrenocorticoids II. - Dr. Perjési Pál
• 38. Insulin and oral hypoglycemic drugs. - Dr. Rozmer Zsuzsanna
• 39. Insulin and oral hypoglycemic drugs. - Dr. Rozmer Zsuzsanna
• 40. Estrogens, Androgens, Progestins I. - Dr. Perjési Pál
• 41. Estrogens, Androgens, Progestins II. - Dr. Perjési Pál
• 42. Estrogens, Androgens, Progestins II. - Dr. Perjési Pál

Gyakorlatok

Szemináriumok

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

D.A. Williams, T.L. Lemke (eds.): Foye's Principles of Medicinal Chemistry, 7th edition, Lippincott Williams & Wilkins, Philadelphia, 2013

Saját oktatási anyag

Attila Almási, Zsuzsanna Rozmer, Pál Perjési: Pharmaceutical Chemistry 1. Laboratory Experiments and Commentary, electronic educational material, PTE 2014

Jegyzet

Ajánlott irodalom

European Pharmacopoeia, EDQM Publication
Lecture notes.

A félév elfogadásának feltételei

Acknowledgement of the course is in accord with the Code of Studies and Examinations. Participation is both the lectures and the practices is obligatory. Maximum three absences can be accepted both from lectures and practices. There is an obligation to write two midterm tests (week 7. and 12.) from the topics of „theory” and „practice”. Students must reach the minimum level of 60% in both cases. Students can have one retake per midterm test. Students have to write at least four mini-tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practical grade. Satisfactory (2) evaluation is the minimum requirement of acknowledgement of the semester.

Félévközi ellenőrzések

The criterion of admission to the exam is the successful completion of the practice carried out in paralell (midsemester grade with the result different from "failed").

Távolmaradás pótlásának lehetőségei

There is no opportunity to make up missed classes.

Vizsgakérdések

Written exam covering the topics of the lectures and the laboratory practices. The result of the first part of the written exam (Minimum Written Test) should be at least 80%. In the case of the third ("C") exam the written exam is evaluated regardless the result of the Minimum Written Test. The list of the possible questions of the Minimum Written Test is announced on the Neptun system. The result of the written exam must be above 60%. The final grade is based on results of the midterm tests and the written exam. Maximum contribution of the results of the midterm tests to the total score of the written exam is 25%. Participation on the first exam is compulsory.

Vizsgáztatók

• Dr. Huber Imre
• Dr. Perjési Pál

Gyakorlatok, szemináriumok oktatói