Pharmaceutical Chemistry 1 - Practice

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2024-2025

Tematika

Introduction to the quality control of substances used in pharmaceutical compounding. Pharmacopoeal analysis of selected inorganic substances.

Előadások

Gyakorlatok

• 1. Laboratory safety and accident protection. The pharmacopoeial nomenclature of substances. Identification and qualitative tests of the European Pharmacopoeia. Limit tests. Acidum hydrochloridum dilutum.
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  2. Laboratory safety and accident protection. The pharmacopoeial nomenclature of substances. Identification and qualitative tests of the European Pharmacopoeia. Limit tests. Acidum hydrochloridum dilutum.

  3. Laboratory safety and accident protection. The pharmacopoeial nomenclature of substances. Identification and qualitative tests of the European Pharmacopoeia. Limit tests. Acidum hydrochloridum dilutum.
• 4. Laboratory safety and accident protection. The pharmacopoeial nomenclature of substances. Identification and qualitative tests of the European Pharmacopoeia. Limit tests. Acidum hydrochloridum dilutum.
• 5. Calculation of results. Experimental errors. Natrii chloridum, Chloraminum.
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  6. Calculation of results. Experimental errors. Natrii chloridum, Chloraminum.

  7. Calculation of results. Experimental errors. Natrii chloridum, Chloraminum.
• 8. Calculation of results. Experimental errors. Natrii chloridum, Chloraminum.
• 9. Inorganic pharmacopoeial substances I. Halogens Natrii bromidum., Kalii bromidum, Ammonii bromidum, Kalii chloridum.
• 10. Inorganic pharmacopoeial substances I. Halogens Natrii bromidum., Kalii bromidum, Ammonii bromidum, Kalii chloridum.
• 11. Inorganic pharmacopoeial substances I. Halogens Natrii bromidum., Kalii bromidum, Ammonii bromidum, Kalii chloridum.
• 12. Inorganic pharmacopoeial substances I. Halogens Natrii bromidum., Kalii bromidum, Ammonii bromidum, Kalii chloridum.
• 13. Inorganic pharmacopoeial substances II. Oxygen group.. Aqua purificata, Hydrogenii peroxidum 30 per centum, Natrii hydroxidum.
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  14. Inorganic pharmacopoeial substances II. Oxygen group.. Aqua purificata, Hydrogenii peroxidum 30 per centum, Natrii hydroxidum.

  15. Inorganic pharmacopoeial substances II. Oxygen group.. Aqua purificata, Hydrogenii peroxidum 30 per centum, Natrii hydroxidum.
• 16. Inorganic pharmacopoeial substances II. Oxygen group.. Aqua purificata, Hydrogenii peroxidum 30 per centum, Natrii hydroxidum.
• 17. Inorganic pharmacopoeial substances III. Sulphur compounds. Natrii thiosulfas, Natrii metabisulfis, Natrii sulfas, Sulphur ad usum externum.
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  18. Inorganic pharmacopoeial substances III. Sulphur compounds. Natrii thiosulfas, Natrii metabisulfis, Natrii sulfas, Sulphur ad usum externum.

  19. Inorganic pharmacopoeial substances III. Sulphur compounds. Natrii thiosulfas, Natrii metabisulfis, Natrii sulfas, Sulphur ad usum externum.
• 20. Inorganic pharmacopoeial substances III. Sulphur compounds. Natrii thiosulfas, Natrii metabisulfis, Natrii sulfas, Sulphur ad usum externum.
• 21. Inorganic pharmacopoeial substances IV. Nitrogen compounds. Ammonii chloridum, Natrii nitris, Kalii nitras, Bismuthi subnitras.
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  22. Inorganic pharmacopoeial substances IV. Nitrogen compounds. Ammonii chloridum, Natrii nitris, Kalii nitras, Bismuthi subnitras.

  23. Inorganic pharmacopoeial substances IV. Nitrogen compounds. Ammonii chloridum, Natrii nitris, Kalii nitras, Bismuthi subnitras.
• 24. Inorganic pharmacopoeial substances IV. Nitrogen compounds. Ammonii chloridum, Natrii nitris, Kalii nitras, Bismuthi subnitras.
• 25. Inorganic pharmacopoeial substances V. Phosphorous compounds. Calcii hydrogenophosphas, Tricalcii phosphas, Natrii dihydrogenophosphas, Dinatrii phosphas
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  26. Inorganic pharmacopoeial substances V. Phosphorous compounds. Calcii hydrogenophosphas, Tricalcii phosphas, Natrii dihydrogenophosphas, Dinatrii phosphas

  27. Inorganic pharmacopoeial substances V. Phosphorous compounds. Calcii hydrogenophosphas, Tricalcii phosphas, Natrii dihydrogenophosphas, Dinatrii phosphas
• 28. Inorganic pharmacopoeial substances V. Phosphorous compounds. Calcii hydrogenophosphas, Tricalcii phosphas, Natrii dihydrogenophosphas, Dinatrii phosphas
• 29. Inorganic pharmacopoeial substances VI. Carbon compounds. Carbo activatus, Calcii carbonas, Natrii carbonas, Natrii hydrogencarbonas.
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  30. Inorganic pharmacopoeial substances VI. Carbon compounds. Carbo activatus, Calcii carbonas, Natrii carbonas, Natrii hydrogencarbonas.

  31. Inorganic pharmacopoeial substances VI. Carbon compounds. Carbo activatus, Calcii carbonas, Natrii carbonas, Natrii hydrogencarbonas.
• 32. Inorganic pharmacopoeial substances VI. Carbon compounds. Carbo activatus, Calcii carbonas, Natrii carbonas, Natrii hydrogencarbonas.
• 33. Inorganic pharmacopoeial substances VII. Pharmaceutical excipients (Seminars). Silicon compounds. Magnesii trisilicas, Silica, colloidal hydrated.
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  34. Inorganic pharmacopoeial substances VII. Pharmaceutical excipients (Seminars). Silicon compounds. Magnesii trisilicas, Silica, colloidal hydrated.

  35. Inorganic pharmacopoeial substances VII. Pharmaceutical excipients (Seminars). Silicon compounds. Magnesii trisilicas, Silica, colloidal hydrated.
• 36. Inorganic pharmacopoeial substances VII. Pharmaceutical excipients (Seminars). Silicon compounds. Magnesii trisilicas, Silica, colloidal hydrated.
• 37. Inorganic pharmacopoeial substances VIII. Alkaline earth metals. Earth metals. Magnesii sulfas, Magnesii subcarbonas, Magnesii oxydum, Acidum boricum, Borax.
• 38. Inorganic pharmacopoeial substances VIII. Alkaline earth metals. Earth metals. Magnesii sulfas, Magnesii subcarbonas, Magnesii oxydum, Acidum boricum, Borax.
• 39. Inorganic pharmacopoeial substances VIII. Alkaline earth metals. Earth metals. Magnesii sulfas, Magnesii subcarbonas, Magnesii oxydum, Acidum boricum, Borax.
• 40. Inorganic pharmacopoeial substances VIII. Alkaline earth metals. Earth metals. Magnesii sulfas, Magnesii subcarbonas, Magnesii oxydum, Acidum boricum, Borax.
• 41. Inorganic pharmacopoeial substances IX. Metals. Aluminii oxidum hydricum, Aluminii sulfas, Zinci oxydum, Zinci chloridum, Ferrosi sulfas, Kalii permanganas.
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  42. Inorganic pharmacopoeial substances IX. Metals. Aluminii oxidum hydricum, Aluminii sulfas, Zinci oxydum, Zinci chloridum, Ferrosi sulfas, Kalii permanganas.

  43. Inorganic pharmacopoeial substances IX. Metals. Aluminii oxidum hydricum, Aluminii sulfas, Zinci oxydum, Zinci chloridum, Ferrosi sulfas, Kalii permanganas.
• 44. Inorganic pharmacopoeial substances IX. Metals. Aluminii oxidum hydricum, Aluminii sulfas, Zinci oxydum, Zinci chloridum, Ferrosi sulfas, Kalii permanganas.
• 45. Physico-chemical parameters influencing the biological effect (solubility, pKa, logP). Determination of logP.
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  46. Physico-chemical parameters influencing the biological effect (solubility, pKa, logP). Determination of logP.

  47. Physico-chemical parameters influencing the biological effect (solubility, pKa, logP). Determination of logP.
• 48. Physico-chemical parameters influencing the biological effect (solubility, pKa, logP). Determination of logP.
• 49. Classification of functional groups and heterocycles (seminar). Assay for Kalii nitras.
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  50. Classification of functional groups and heterocycles (seminar). Assay for Kalii nitras.

  51. Classification of functional groups and heterocycles (seminar). Assay for Kalii nitras.
• 52. Classification of functional groups and heterocycles (seminar). Assay for Kalii nitras.
• 53. Basics of stereochemistry. Stereochemistry of morphine and derivatives.
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  54. Basics of stereochemistry. Stereochemistry of morphine and derivatives.

  55. Basics of stereochemistry. Stereochemistry of morphine and derivatives.
• 56. Basics of stereochemistry. Stereochemistry of morphine and derivatives.

Szemináriumok

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

Saját oktatási anyag

Attila Almási, Zsuzsanna Rozmer, Pál Perjési: Pharmaceutical Chemistry I. Laboratory Experiments and Commentary, electronic educational material, PTE 2014.

Jegyzet

Pharmaceutical Chemistry Practice I., Laboratory manual, University of Pécs, 2015.

Ajánlott irodalom

A félév elfogadásának feltételei

Acknowledgement of the course is in accord with the Code of Studies and Examinations. Participation in the practices is obligatory. Maximum three absences can be accepted. Students have to write at least four short tests on the practices. The average of the results must be at least 50%. Quantitative measurements should be carried out with the acceptance level of 70%! The practical work (results of the written tests and the experimental work) is evaluated by a practice grade.

Félévközi ellenőrzések

The short practical test can be made up on the next practical.

Távolmaradás pótlásának lehetőségei

There is no opportunity to make up missed practices.

Vizsgakérdések

Questions of the above short tests are from the topics of the practical and seminary.

Vizsgáztatók

Gyakorlatok, szemináriumok oktatói

• Almási Attila
• Mészáros Petra