Pharmaceutical Chemistry 4 - Practice

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2024-2025

Tematika

Introduction to quality control of complex pharmaceutical preparations. Application of instrumental methods in pharmacopoeal quality control of pharmaceutical preparations.

Előadások

Gyakorlatok

• 1. Stability tests. Analysis of degradation of acetylsalicylic acid.
• ...

  2. Stability tests. Analysis of degradation of acetylsalicylic acid.

  3. Stability tests. Analysis of degradation of acetylsalicylic acid.
• 4. Stability tests. Analysis of degradation of acetylsalicylic acid.
• 5. Sample preparation. Extaction techniques. Liquid-liquid extraction of salycilic acid.
• ...

  6. Sample preparation. Extaction techniques. Liquid-liquid extraction of salycilic acid.

  7. Sample preparation. Extaction techniques. Liquid-liquid extraction of salycilic acid.
• 8. Sample preparation. Extaction techniques. Liquid-liquid extraction of salycilic acid.
• 9. Bases of chromatographic separations I. Detection of methanol in ethanol by TLC method. Separation of albumine and sodium chloride by gel chromatographic method.
• ...

  10. Bases of chromatographic separations I. Detection of methanol in ethanol by TLC method. Separation of albumine and sodium chloride by gel chromatographic method.

  11. Bases of chromatographic separations I. Detection of methanol in ethanol by TLC method. Separation of albumine and sodium chloride by gel chromatographic method.
• 12. Bases of chromatographic separations I. Detection of methanol in ethanol by TLC method. Separation of albumine and sodium chloride by gel chromatographic method.
• 13. Bases of chromatographic separations II. Application of gas chromatography in the analysis of pharmaceutical substances.
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  14. Bases of chromatographic separations II. Application of gas chromatography in the analysis of pharmaceutical substances.

  15. Bases of chromatographic separations II. Application of gas chromatography in the analysis of pharmaceutical substances.
• 16. Bases of chromatographic separations II. Application of gas chromatography in the analysis of pharmaceutical substances.
• 17. Bases of chromatographic separations III. Application of the high performance liquid chromatography in the analysis of pharmaceutical substances.
• ...

  18. Bases of chromatographic separations III. Application of the high performance liquid chromatography in the analysis of pharmaceutical substances.

  19. Bases of chromatographic separations III. Application of the high performance liquid chromatography in the analysis of pharmaceutical substances.
• 20. Bases of chromatographic separations III. Application of the high performance liquid chromatography in the analysis of pharmaceutical substances.
• 21. Vitamines. Detremination of cyanocobalaminum by UV-Vis and HPLC methods.
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  22. Vitamines. Detremination of cyanocobalaminum by UV-Vis and HPLC methods.

  23. Vitamines. Detremination of cyanocobalaminum by UV-Vis and HPLC methods.
• 24. Vitamines. Detremination of cyanocobalaminum by UV-Vis and HPLC methods.
• 25. Identification of multi-component drug mixtures I. General principles. Sample preparation. Determination of bases in drug mixtures I. Pulvis antispasticus.
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  26. Identification of multi-component drug mixtures I. General principles. Sample preparation. Determination of bases in drug mixtures I. Pulvis antispasticus.

  27. Identification of multi-component drug mixtures I. General principles. Sample preparation. Determination of bases in drug mixtures I. Pulvis antispasticus.
• 28. Identification of multi-component drug mixtures I. General principles. Sample preparation. Determination of bases in drug mixtures I. Pulvis antispasticus.
• 29. Identification of multi-component drug mixtures II. Determination of bases in drug mixtures II. Pulvis antidoloricus. Pulvis astmaliticus. Pulvis codacetini. Application of HPLC.
• ...

  30. Identification of multi-component drug mixtures II. Determination of bases in drug mixtures II. Pulvis antidoloricus. Pulvis astmaliticus. Pulvis codacetini. Application of HPLC.

  31. Identification of multi-component drug mixtures II. Determination of bases in drug mixtures II. Pulvis antidoloricus. Pulvis astmaliticus. Pulvis codacetini. Application of HPLC.
• 32. Identification of multi-component drug mixtures II. Determination of bases in drug mixtures II. Pulvis antidoloricus. Pulvis astmaliticus. Pulvis codacetini. Application of HPLC.
• 33. Identification of multi-component drug mixtures III. Determination of bases in drug mixtures III. Pulvis cholagogus, Unguentum haemorrhoidale, Suppositorium analgeticum.
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  34. Identification of multi-component drug mixtures III. Determination of bases in drug mixtures III. Pulvis cholagogus, Unguentum haemorrhoidale, Suppositorium analgeticum.

  35. Identification of multi-component drug mixtures III. Determination of bases in drug mixtures III. Pulvis cholagogus, Unguentum haemorrhoidale, Suppositorium analgeticum.
• 36. Identification of multi-component drug mixtures III. Determination of bases in drug mixtures III. Pulvis cholagogus, Unguentum haemorrhoidale, Suppositorium analgeticum.
• 37. Identification of multi-component drug mixtures IV. Determination of acids in drug mixtures I. Spiritus iodosalicylatus, Spiritus salicylatus cum resorcino.
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  38. Identification of multi-component drug mixtures IV. Determination of acids in drug mixtures I. Spiritus iodosalicylatus, Spiritus salicylatus cum resorcino.

  39. Identification of multi-component drug mixtures IV. Determination of acids in drug mixtures I. Spiritus iodosalicylatus, Spiritus salicylatus cum resorcino.
• 40. Identification of multi-component drug mixtures IV. Determination of acids in drug mixtures I. Spiritus iodosalicylatus, Spiritus salicylatus cum resorcino.
• 41. Identification of multi-component drug mixtures V. Determination of acids in drug mixtures II. Pulvis chinacisalis c. vitamino C, Pulvis somniferens.
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  42. Identification of multi-component drug mixtures V. Determination of acids in drug mixtures II. Pulvis chinacisalis c. vitamino C, Pulvis somniferens.

  43. Identification of multi-component drug mixtures V. Determination of acids in drug mixtures II. Pulvis chinacisalis c. vitamino C, Pulvis somniferens.
• 44. Identification of multi-component drug mixtures V. Determination of acids in drug mixtures II. Pulvis chinacisalis c. vitamino C, Pulvis somniferens.
• 45. Drug metabolism (seminary).
• ...

  46. Drug metabolism (seminary).

  47. Drug metabolism (seminary).
• 48. Drug metabolism (seminary).
• 49. In vitro and in vivo methods in the drug metabolism studies. Acetylsalicylic acid, 4-nitrophenol.
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  50. In vitro and in vivo methods in the drug metabolism studies. Acetylsalicylic acid, 4-nitrophenol.

  51. In vitro and in vivo methods in the drug metabolism studies. Acetylsalicylic acid, 4-nitrophenol.
• 52. In vitro and in vivo methods in the drug metabolism studies. Acetylsalicylic acid, 4-nitrophenol.
• 53. Chemical and structural classification of functional groups and heterocycles. (seminary).
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  54. Chemical and structural classification of functional groups and heterocycles. (seminary).

  55. Chemical and structural classification of functional groups and heterocycles. (seminary).
• 56. Chemical and structural classification of functional groups and heterocycles. (seminary).

Szemináriumok

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

D.A. Williams, T.L. Lemke (eds.): Foye's Principles of Medicinal Chemistry, 7th edition, Lippincott Williams & Wilkins, Philadelphia, 2013.

Saját oktatási anyag

Attila Almási, Zsuzsanna Rozmer, Pál Perjési: Pharmaceutical Chemistry 1. Laboratory Experiments and Commentary, Electronic educational material, PTE 2014.

Jegyzet

Pharmaceutical Chemistry Practice 2, Laboratory manual, University of Pécs, 2015.

Ajánlott irodalom

European Pharmacopoeia. EDQM Publication.

Lecture notes.

A félév elfogadásának feltételei

Acknowledgement of the course is in accord with the Code of Studies and Examinations. Participation in the practices is obligatory. Maximum three absences can be accepted. Students have to write at least four short tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practice grade.

Félévközi ellenőrzések

Students have to write at least four short tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practice grade.

Távolmaradás pótlásának lehetőségei

There is no opportunity to make up missed classes.

Vizsgakérdések

N/A

Vizsgáztatók

Gyakorlatok, szemináriumok oktatói

• Harmath Lilla Édua
• Rozmer Zsuzsanna
• Tyukodi Levente