Pharmaceutical Biology 1

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2026-2027

Tematika

The 2-semester Biology course provides the essential fundamental molecular biological knowledge for the pharmaceutical students. In the first semester students will study the structure and main functions of the living eukaryotic cells. We will discuss briefly the structural features of prokaryotes as well as viruses. The majority of the topics will deal with the information storage and utilization of the cells, and the regulation of these processes.

Előadások

• 1. Introduction. - Pandur Edina
• 2. Building blocks of the cell. - Tamási Kitti
• 3. Genom and gene expression. - Jánosa Gergely
• 4.

  Tools and techniques in molecular biology I.

  - Tamási Kitti
• 5.

  Tools and techniques in molecular biology II.

  - Tamási Kitti
• 6. Prokaryotic and eukaryotic cells. - Jánosa Gergely
• 7.

  Stem cells.

  - Tamási Kitti
• 8. The nucleus and the cellular membranes. - Jánosa Gergely
• 9. Structure of DNA. - Pandur Edina
• 10. Chromosomes and genomes. - Pandur Edina
• 11. Mitochondrium: structure and function. Mitochondrial DNA. - Jánosa Gergely
• 12. Cytoplasmic organelles: endoplasmic reticulum, Golgi apparatus, lysosomes. - Pandur Edina
• 13.

  Replication I.

  - Pandur Edina
• 14.

  Replication II.

  - Pandur Edina
• 15.

  DNA repair mechanisms.

  - Pandur Edina
• 16. Transcription in prokaryotic cells. - Sipos Katalin
• 17. Eukaryotic transcription: mRNA, rRNA, tRNA - Sipos Katalin
• 18.

  Genetic code.

  - Tamási Kitti
• 19. Regulation of transcription. - Jánosa Gergely
• 20. Transcription factors. - Pandur Edina
• 21.

  First midterm exam.

  - Pap Ramóna, Pandur Edina, Tamási Kitti, Jánosa Gergely, Horváth Adrienn (Farmakognózia)
• 22. Structure and functions of ribosomes. tRNA - Pandur Edina
• 23. Steps of translation. - Pandur Edina
• 24. Regulation of translation - Pandur Edina
• 25. Protein analysing methods - Jánosa Gergely
• 26. Gene regulation: prokaryotes. - Jánosa Gergely
• 27. Regulation of gene expression in eukaryotes - Jánosa Gergely
• 28. Regulation of gene expression in eukaryotes II. - Jánosa Gergely
• 29. Posttranslational modifications. - Pandur Edina
• 30.

  Degradation of proteins.

  - Tamási Kitti
• 31.

  Intracellular trafficing of proteins: nucleus, mitochondrion.

  - Pandur Edina
• 32.

  Intracellular trafficing of proteins: ER.

  - Pandur Edina
• 33. Vesicular transport - Pandur Edina
• 34.

  Antibiotics.

  - Tamási Kitti
• 35.

  Second midterm exam.

  - Jánosa Gergely, Pandur Edina, Pap Ramóna, Tamási Kitti, Horváth Adrienn (Farmakognózia)
• 36.

  Proteins-summary.

  - Jánosa Gergely
• 39.

  Mitosis I

  - Jánosa Gergely
• 40.

  Mitosis II

  - Jánosa Gergely
• 41.

  Meiosis I

  - Pandur Edina
• 42.

  Meiosis II

  - Pandur Edina
• 37.

  Cell cycle I.

  - Jánosa Gergely
• 38.

  Cell cycle II.

  - Jánosa Gergely

Gyakorlatok

Szemináriumok

• 5.

  Extracellular matrix

  - Pandur Edina
• 1.

  Macromolecules as building blocks of living cells.

  - Tamási Kitti
• 2.

  Separation techniques.

  - Jánosa Gergely
• 3.

  Detection in molecular biology.

  - Tamási Kitti
• 4.

  Cytoskeleton.

  - Pandur Edina
• 6.

  Bases of PCR.

  - Jánosa Gergely
• 7.

  Sequencing methods.

  - Jánosa Gergely
• 8.

  Questions and answers, preparing for the midterm exam.

  - Pandur Edina
• 9.

  Viruses.

  - Tamási Kitti
• 10.

  Human Genome Project.

  - Tamási Kitti
• 11.

  Molecular biological methods in Pharmaceutical research.

  - Pandur Edina
• 12.

  Protein tageting: summary

  - Pandur Edina
• 13.

  Mechanisms of action of the antibiotics.

  - Tamási Kitti
• 14.

  Consultation, preparing for the final exam.

  - Pandur Edina

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

Saját oktatási anyag

The materials of the lectures and seminars will appear on Neptun Meet Street.

Jegyzet

Electronic note on Pharmaceutical Biology can be found on Neptun Meet Street.

Ajánlott irodalom

Cooper GM: The Cell: A Molecular Approach, 2nd edition, PubMed

Elliott WH, Elliott DC: Biochemistry and Molecular Biology, 3rd edition

Thompson & Thompson: Genetics in Medicine

Crai NL: Molecular Biology, Principles of Genome Function, OUP 2010

Young ID: Medical Genetics

A félév elfogadásának feltételei

Writing two midterm exams during the semester.

Félévközi ellenőrzések

Two midterm exams are compulsory during the semester.

Távolmaradás pótlásának lehetőségei

According to personal agreement

Vizsgakérdések

No examination questions are assigned. The material for the examination is based on the lectures and seminars. Examination questions will be discussed in consultation classes during the semester.

The exam will include a biology concept pop-up (minimum requirement test), for which a glossary of terms will be issued at the beginning of the semester.

Vizsgáztatók

• Jánosa Gergely
• Pandur Edina
• Pap Ramóna
• Tamási Kitti

Gyakorlatok, szemináriumok oktatói

• Jánosa Gergely
• KURZUSHOZ RENDELT OKTATÓ
• Pandur Edina
• Pap Ramóna
• Tamási Kitti