Medical Biochemistry

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2026-2027

Tematika

The Medical Biochemistry course is a semester course, ending with an oral exam. Knowledge of the metabolic processes learned in the Biochemistry subject is necessary for the Medical Biochemistry subject, although the Biochemistry final exam is not a prerequisite for taking the subject. The course aims to provide insight into how the living organism (at the molecular level) performs its physiological functions or reacts to various environmental stimuli, physiological and pathological conditions. During the semester, we present the organ- and organelle-specific aspects of metabolism, as well as discuss the biochemical background of related disorders/diseases.

Előadások

• 1. Introduction / Division of metabolic tasks between the organs - Bognár Zita
• 2. Lipoproteins - Fekete Katalin
• 3. Nutrition: macro- and micronutrients - Szabó Éva (Biokémia)
• 4. Trace elements, deficiency diseases - Szabó Éva (Biokémia)
• 5. Metabolic diseases of the carbohydrates - Bagóné Vántus Viola
• 6. Disorders of amino acid metabolism - Veres Balázs
• 7. Lipid and nucleotide metabolic diseases - Szabó Éva (Biokémia)
• 8. Biochemical principles of pH regulation - Berente Zoltán
• 9. Biochemistry of kidney function - Takátsy Anikó
• 10. Molecular mechanisms of mitochondrial function - Veres Balázs
• 11. Oxidative stress induced signaling - Jávor-Hocsák Enikő
• 12. Biochemistry of inflammation - Rauch Tibor Attila
• 13. Bone and joint diseases - Rauch Tibor Attila
• 14. Iron metabolism in the human body - Jávor-Hocsák Enikő
• 15. Haemoglobinopathies, hyperbilirubinaemia - Márk László
• 16. Special functions of the liver, biotransformation processes - Veres Balázs
• 17. Biochemical consequences of alcohol consumption - Antus Csenge Petra
• 18. The microbiome - Bagóné Vántus Viola
• 19. Diseases of the gastrointestinal tract - Kőszegi Balázs
• 20. Biochemistry of the pancreas - Takátsy Anikó
• 21. Molecular mechanisms of sugar absorption - Nagyné Kiss Gyöngyi
• 22. Biochemical background of diabetes mellitus - Nagyné Kiss Gyöngyi
• 23.

  Regulation of body weight, diets

  - Szabó Éva (Biokémia)
• 24.

  Sport, liefstyle

  - Márk László
• 25. Biochemistry of the blood vessels - Bognár Zita
• 26. Molecular mechanisms of blood pressure regulation - Tapodi Antal
• 27. Molecular mechanisms of heart function - Marquettené Bock Ildikó
• 28. Functions of the cytoskeleton - Berente Zoltán
• 29. Cell cycle and its regulation, therapeutic possibilities - Fekete Katalin
• 30. Mechanisms of cell death - Veres Balázs
• 31. Proteins and functions of the extracellular matrix - Nagyné Kiss Gyöngyi
• 32. Matrix metalloproteinases - Marquettené Bock Ildikó
• 33. Tumour biochemistry - Balogi Zsolt
• 34. Biochemistry of sensing - Jávor-Hocsák Enikő
• 35. Nervous system I. - Gallyas Ferenc
• 36. Nervous system II. - Gallyas Ferenc
• 37. Nervous system III. - Gallyas Ferenc
• 38. Characteristics of the endoplasmic reticulum - Berente Zoltán
• 39. Functions of Golgi, lysosomes and peroxisomes - Tapodi Antal
• 40. Biochemistry of senescence - Kőszegi Balázs
• 41. Metabolic pathways, metabolites in new roles - Antus Csenge Petra
• 42.

  Molecular background of personalized medicine

  - Márk László

Gyakorlatok

• 1. Analysis of body fluids
• 2. Analysis of body fluids
• 3. Metabolic disorders
• 4. Metabolic disorders
• 5. Disorders of acid-base balance; pH measurement
• 6. Disorders of acid-base balance; pH measurement
• 7. Biochemistry of organs
• 8. Biochemistry of organs
• 9. Determination of blood glucose
• 10. Determination of blood glucose
• 11. Blood-liver-alcohol; (haemoglobin, iron, alcohol, biotransformation)
• 12. Blood-liver-alcohol; (haemoglobin, iron, alcohol, biotransformation)
• 13. Determination of blood cholesterol
• 14. Determination of blood cholesterol
• 15. Acquired metabolic diseases (obesity, diabetes mellitus, atherosclerosis)
• 16. Acquired metabolic diseases (obesity, diabetes mellitus, atherosclerosis)
• 17. Determination of uric acid
• 18. Determination of uric acid
• 19. Cellular stress response, ROS, inflammation
• 20. Cellular stress response, ROS, inflammation
• 21. Student presentations
• 22. Student presentations
• 23. Student presentations
• 24. Student presentations
• 25. Cholinesterase detemination, consultation
• 26. Cholinesterase determination, consultation
• 27. Cell cycle and cancer
• 28. Cell cycle and cancer

Szemináriumok

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

Nelson, Cox: Lehninger Principles of Biochemistry, 7th edition, W.H. Freeman, 2017.

Saját oktatási anyag

https://potepedia.aok.pte.hu/en

Jegyzet

https://potepedia.aok.pte.hu/en

Ajánlott irodalom

Berg, Tymoczko, Stryer: Biochemistry, 8th edition, W.H. Freeman, 2015.

Devlin: Textbook of Biochemistry with Clinical Correlations, 7th edition, Wiley, 2010.

Lieberman, Marks: Marks' Basic Medical Biochemistry - A Clinical Approach, 4th edition, Lippincott, 2013

A félév elfogadásának feltételei

No more than three absences from the laboratory practices.

Holding an oral presentation about a given disorder provided in the presentation topic list and achieve at least 1 point.
Take at least 10 of the 12 short tests to be written in the first 10 minutes of the exercises. Achieving a minimum of 7 points during the tests.

Félévközi ellenőrzések

Holding an oral presentation about a specific disorder from the presentation topic list.
Starting from week 3, there will be 12 short tests to write in the first 10 minutes of each exercise.

Távolmaradás pótlásának lehetőségei

During the semester, we will give students the opportunity to make up for one missed practice/demos with the short test during the second exam week.

Vizsgakérdések

http://aok.pte.hu/en/egyseg/oktatasianyagok/20
https://potepedia.aok.pte.hu/en

The semester ends with an oral semester exam that is preceded by a written test consisting of 7 questions from the minimum (MRT) questions. Those who score at least 20 points out of the possible 28 on the MRT are eligible to draw a topic for the oral exam.

After passing the written MRT test, the student draws an oral topic card that includes both A and B parts. The final grade is determined by the performance on the oral exam.

Vizsgáztatók

• Agócs Attila
• Antus Csenge Petra
• Bagóné Vántus Viola
• Berente Zoltán
• Bognár Zita
• Fekete Katalin
• Gallyas Ferenc
• Jávor-Hocsák Enikő
• Kálmán Nikoletta
• Kiss Bence
• Kőszegi Balázs
• Nagyné Kiss Gyöngyi
• Radnai Balázs (Biokémia)
• Szabó Aliz
• Takátsy Anikó
• Tapodi Antal
• Veres Balázs

Gyakorlatok, szemináriumok oktatói

• Antus Csenge Petra
• Bagóné Vántus Viola
• Berente Zoltán
• Bognár Zita
• Fekete Katalin
• Jávor-Hocsák Enikő
• Kiss Bence
• Kőszegi Balázs
• KURZUSHOZ RENDELT OKTATÓ
• Nagyné Kiss Gyöngyi
• Takátsy Anikó
• Tapodi Antal
• Veres Balázs