Molecular biology of cancer

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2026-2027

Tematika

The course examines the genetic, epigenetic, and cellular mechanisms underlying tumorigenesis, with particular emphasis on the dysregulation of signaling networks and the functional consequences of oncogene and tumor suppressor gene mutations. Students will gain insight into the interactions among molecular mechanisms, their network-level organization, and their clinical relevance. Special attention is given to recent advances in the field, the role of the tumor microenvironment, molecular heterogeneity, and the mechanistic basis of targeted and precision therapies. The course aims to enable students to interpret the complex processes of cancer development from a systems-level perspective and to apply the acquired knowledge in their further studies.

Előadások

• 1. General characteristics of tumors - Pap Marianna
• 2. General characteristics of tumors - Pap Marianna
• 3. The role of intracellular receptor-mediated signal transduction in hormone-dependent tumors - Pap Marianna
• 4. The role of intracellular receptor-mediated signal transduction in hormone-dependent tumors - Pap Marianna
• 5. The role of cell surface receptor-mediated signal transduction processes in tumor formation - Pap Marianna
• 6. The role of cell surface receptor-mediated signal transduction processes in tumor formation - Pap Marianna
• 7. The role of apoptosis signal transduction processes in tumor formation - Pap Marianna
• 8. The role of apoptosis signal transduction processes in tumor formation - Pap Marianna
• 9. The role of DNA tumor viruses in tumor formation - Pap Marianna
• 10. The role of DNA tumor viruses in tumor formation - Pap Marianna
• 11. The role of RNA tumor viruses in tumor formation - Pap Marianna
• 12. The role of RNA tumor viruses in tumor formation - Pap Marianna
• 13. The role of gain-of-function mutations in tumor formation - Pap Marianna
• 14. The role of gain-of-function mutations in tumor formation - Pap Marianna
• 15. The role of loss-of-function mutations in tumor formation - Pap Marianna
• 16. The role of loss-of-function mutations in tumor formation - Pap Marianna
• 17. Molecular model of multistep carcinogenesis - Pap Marianna
• 18. Molecular model of multistep carcinogenesis - Pap Marianna
• 19. Clinical model of multistep carcinogenesis - Pap Marianna
• 20. Clinical model of multistep carcinogenesis - Pap Marianna
• 21. Therapeutic targets and targeted therapies - Pap Marianna
• 22. Therapeutic targets and targeted therapies - Pap Marianna
• 23. Test - Pap Marianna
• 24. Test - Pap Marianna

Gyakorlatok

Szemináriumok

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

Saját oktatási anyag

Lectures ppt presentations

Jegyzet

Ajánlott irodalom

A félév elfogadásának feltételei

-

Félévközi ellenőrzések

-

Távolmaradás pótlásának lehetőségei

no possibility for make up

Vizsgakérdések

-

Vizsgáztatók

Gyakorlatok, szemináriumok oktatói