Genetic Background of Gene Manipulation I

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2024-2025

Tematika

The subject introduces the basics of genetics and the basic principles of inheritance (e.g. Mendelian and non-Mendelian inheritance, sex-linked inheritance, etc.). During the course, the properties, methodologies, and statistical background of linkage studies are discussed (e.g. allele frequency, Hardy-Weinberg equilibrium, etc.). The course describes the characteristics, structure, and variations of the genome of the important model animals used in biotechnology. The course gives an overview of the molecular mechanism and regulation of gene expression in prokaryotes and eukaryotes. The course presents the basic technologies applied in genetics; during the practice, students will become familiar with these methods.

Előadások

• 2. Mitosis and meiosis I. - Garai Kitti
• 1. Introduction: Concepts of Genetics - Garai Kitti
• 3. Mitosis and meiozis II. - Garai Kitti
• 4. Mendelian principles I - Garai Kitti
• 5. Mendelian principles II - Garai Kitti
• 6. Mendelian genetics - Garai Kitti
• 7. Independent assortment - Garai Kitti
• 8. Laws of probability - Garai Kitti
• 9. Patterns of inheritance - Garai Kitti
• 10. Extension of Mendelian genetics - alleles and sex lined inheritance - Garai Kitti
• 11. Chromosome mapping in Eukaryotes I. - Garai Kitti
• 12. Chromosome mapping in Eukaryotes II. - Garai Kitti
• 13. Genetic analysis and mapping in Bacteria and bacteriophages I. - Garai Kitti
• 14. Genetic analysis and mapping in Bacteria and bacteriophages II. - Garai Kitti
• 15. Sex determination and sex chromosomes - Garai Kitti
• 16. Chromosomal mutations I. - Garai Kitti
• 17. Chromosomal mutations II. - Garai Kitti
• 18. Extracellular inheritance - Garai Kitti
• 19. DNA structure, organization, replication and analysis I. - Garai Kitti
• 20. DNA structure, organization, replication and analysis II. - Garai Kitti
• 21. DNA replication and recombination I. - Garai Kitti
• 22. DNA replication and recombination II. - Garai Kitti
• 23. DNA organization in chromosomes I. - Garai Kitti
• 24. DNA organization in chromosomes II. - Garai Kitti
• 25. Genetic code and transcription - Garai Kitti
• 26. Genetic code and transcription II. - Garai Kitti
• 27. Translation and proteins I. - Garai Kitti
• 28. Translation and proteins II. - Garai Kitti

Gyakorlatok

• 1. Exploring genomics I. - Ádám Zoltán Mihály
• 2. Exploring genomics II. - Ádám Zoltán Mihály
• 3. Independent assortment I. - Ádám Zoltán Mihály
• 4. Independent assortment II. - Ádám Zoltán Mihály
• 5. Laws of probability I. - Ádám Zoltán Mihály
• 6. Laws of probability II. - Ádám Zoltán Mihály
• 7. Laws of probability III. - Ádám Zoltán Mihály
• 8. Chi-Square analysis I. - Ádám Zoltán Mihály
• 9. Chi-Square analysis II. - Ádám Zoltán Mihály
• 10. Chi-Square analysis III. - Ádám Zoltán Mihály
• 11. Mendelian inheritance in man - test or not to test - Garai Kitti
• 12. Modern approaches to understanding gene function - Garai Kitti
• 13. Genetic background and phenotype I. - Draskóczi Lilla Gréta
• 14. Genetic background and phenotype II. - Draskóczi Lilla Gréta
• 15. Environmental effects on genetic background and phenotype I. - Ádám Zoltán Mihály
• 16. Environmental effects on genetic background and phenotype II. - Ádám Zoltán Mihály
• 17. Environmental effects on genetic background and phenotype III. - Ádám Zoltán Mihály
• 18. Environmental effects on genetic background and phenotype IV. - Ádám Zoltán Mihály
• 19. Human chromosome maps and diseases I. - Garai Kitti
• 20. Human chromosome maps and diseases II. - Garai Kitti
• 21. Human chromosome maps and diseases III. - Garai Kitti
• 22. Human chromosome maps and diseases IV. - Garai Kitti
• 23. Multidrug resistance in bacteria I. - Garai Kitti
• 24. Human chromosome maps and diseases II. - Garai Kitti
• 25. Modern approaches to understanding gene function - Drosophila I. - Ádám Zoltán Mihály
• 26. Modern approaches to understanding gene function - Drosophila II. - Ádám Zoltán Mihály
• 27. Gene expression - RNA and protein I. - Ádám Zoltán Mihály
• 28. Gene expression - RNA and protein II. - Ádám Zoltán Mihály

Szemináriumok

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

Saját oktatási anyag

Lecture ppt-s and seminar material based on the recommended literature

Jegyzet

Ajánlott irodalom

Klug et al. - Concepts of Genetics 12th Edition

Benjamin A. Pierce - Genetics_ A Conceptual Approach 7th Edition (2020)

A félév elfogadásának feltételei

Midterm test - above 51%, regular attendance and cooperative work to lectures and seminars, documented on the attendance sheet.

Félévközi ellenőrzések

One midterm test on the 6th week of the semester. If failed, two additional opportunities are provided for the students. The test is accepted if the student reached 51% on the test.

Távolmaradás pótlásának lehetőségei

Not possible

Vizsgakérdések

Exam topics will be available on Teams and cover the topic list.

Vizsgáztatók

• Ádám Zoltán Mihály
• Garai Kitti
• Pongrácz Judit Erzsébet

Gyakorlatok, szemináriumok oktatói

• Ádám Zoltán Mihály
• Draskóczi Lilla Gréta
• Garai Kitti