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Evolutionary Immunobiology

Daten

Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2021-2022

Lehrbeauftragte/r

  • Dr. Péter András ENGELMANN

    associate professor,
    Department of Immunology and Biotechnology

Semesterwochenstunden

Vorlesungen: 0

Praktika: 0

Seminare: 12

Insgesamt: 12

Fachangaben

  • Kode des Kurses: OAF-EVO-T
  • 1 kredit
  • General Medicine
  • Optional modul
  • autumn
Voraussetzungen:

OAA-MB2-T completed , OAA-IMM-T completed

Zahl der Kursteilnehmer für den Kurs:

min. 3 – max. 30

Thematik

The course describes the molecular and cellular elements of innate/adaptive immunity in their evolutionary contexts. Moreover, it discusses the ancient immune functions (phagocytosis, antimicrobial molecules, antiviral RNA interference) along with the newest research data about the development of adaptive immunity.

Vorlesungen

Praktika

Seminare

  • 1. Definition of the topics and course, comparison of innate and adaptive immunity
  • 2. Pattern recognition receptors: Toll, Croquemort and others
  • 3. Conserved signal transduction pathways in immunology
  • 4. Cellular immune functions of innate immunity: phagocytosis, cytotoxicity, encapsulation-, capsule-, granulomeformation
  • 5. Humoral immune components I: antimicrobial molecules, peptides. Prophenoloxidase cascade, coagulation.
  • 6. Humoral immune components II: Acute-phase proteins, complement-evolution
  • 7. Humoral immune components III: evolution of cytokines and chemokines
  • 8. Sounds of Silence or the role of RNA interference (RNAi) in innate immunity, antiviral innate immunity
  • 9. Alternative adaptive immunity in invertebrates and in ancient vertebrates?
  • 10. Histoincompatibility in invertebrates, MHC-evolution
  • 11. Immunological twilight-zone - The appearance of adaptive immunity, Immunological triumvirate: RAG-time: immunglobulin, TCR development in the context of phylogenesis
  • 12. Phylogenetical development of vertebrate immune organs, host-pathogen co-evolution

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Vom Institut veröffentlichter Lehrstoff

www.immbio.hu

Skript

Empfohlene Literatur

http://www.sciencedirect.com/science/journal/0145305X

Voraussetzung zum Absolvieren des Semesters

Referral, max. 2 absences from the seminars

Semesteranforderungen

Presentation

Möglichkeiten zur Nachholung der Fehlzeiten

Individual preparation

Prüfungsfragen

-

Prüfer

Praktika, Seminarleiter/innen

  • Dr. Engelmann Péter András
Rólunk