Pathophysiology of Blood Cells

Daten

Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2024-2025

Thematik

The course focuses on the pathophysiology of erythropoiesis and on the structural and functional abnormalities of blood cells at a preclinical level. In addition to those of red blood cells, functions and disorders of leukocytes and platelets are discussed. Related functional and clinical conditions together with the pathophysiological basis of possible therapies will also be included. Theory is complemented by case histories.

Vorlesungen

• 1. The functions of blood. Erythropoiesis, leukopoiesis, thrombopoiesis. Case histories. - Balaskó Márta
• 2. Polycythemia vera and spuria: etiology, pathogenesis and complications. - Balaskó Márta
• 3. Morphology of red blood cells, corpuscular hemolytic anemias. - Balaskó Márta
• 4. Sickle cell anemia: etiology, pathogenesis, pathophysiology of therapeutic possibilities. - Balaskó Márta
• 5. Thalassemias: etiology, complications, treatment. Case histories. - Balaskó Márta
• 6. Extracorpuscular hemolytic anemias. Case histories. - Balaskó Márta
• 7. Abnormalities of the neutrophil granulocytes. Case histories. - Balaskó Márta
• 8. Abnormalities of eosinophil and basophil granulocytes. - Balaskó Márta
• 9. Abnormalities of lymphocytes. Case studies. - Balaskó Márta
• 10. Platelets: structure, functions and related pathophysiology. - Balaskó Márta
• 11. Pathophysiological significance of endothel cells. Case histories. - Balaskó Márta
• 12. Test. Case histories. - Balaskó Márta

Praktika

Seminare

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Vom Institut veröffentlichter Lehrstoff

Lecture slides are uploaded to Teams.

Skript

Empfohlene Literatur

Hoffbrand, Moss and Pettit: Essential Haematology, 5th edition, Blackwell 2006 ISBN 1-4051-3649-9

Székely Miklós (editor) Basic concepts in pathopysiology. Medicina Publishing House Budapest, 2019.

Voraussetzung zum Absolvieren des Semesters

None

Semesteranforderungen

None

Möglichkeiten zur Nachholung der Fehlzeiten

An essay on the topic of the missed lecture.

Prüfungsfragen

The functions of blood. Erythropoiesis, leukopoiesis, thrombopoiesis.

Polycythemia vera and spuria: etiology, pathogenesis and complications.

Morphology of red blood cells, corpuscular hemolytic anemias.

Sickle cell anemia: etiology, pathogenesis, pathophysiology of therapeutic possibilities.

Thalassemias: etiology, complications, treatment. Case histories.

Extracorpuscular hemolytic anemias.

Abnormalities of the neutrophil granulocytes.

Abnormalities of eosinophil and basophil granulocytes.

Abnormalities of lymphocytes.

Platelets: structure, functions and related pathophysiology.

Pathophysiological significance of endothel cells.

The grade depends on the result of the final test.

Prüfer

Praktika, Seminarleiter/innen