Inorganic Pharmaceutical Chemistry - Practice

Daten

Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2022-2023

Thematik

The aim of the course is acquiring the basis of modern inorganic chemistry with adaptation of the principles to understand the physical and chemical properties of the most important pharmacy-related elements and inorganic compounds. The subject devotes special attention to the inorganic compounds (active pharmaceutical ingredients and excipients) listed in the Pharmacopoeia. The practices provide the experimental background of these educational goals.

Vorlesungen

Praktika

• 1. Laboratory safety. Introduction and handover of laboratory equipment. Weighing.
• 2. Laboratory safety. Introduction and handover of laboratory equipment. Weighing.
• 3. Laboratory safety. Introduction and handover of laboratory equipment. Weighing.
• 4. Basic principles of calculations I: Concentrations. Delivering liquids. Preparation of solutions. Measuring density.
• 5. Basic principles of calculations I: Concentrations. Delivering liquids. Preparation of solutions. Measuring density.
• 6. Basic principles of calculations I: Concentrations. Delivering liquids. Preparation of solutions. Measuring density.
• 7. Basic principles of calculations II: Dilutions. Purification of inorganic compounds I. Decantation, Filtration. Recrystallization. Purification of alum by recrystallization I.
• 8. Basic principles of calculations II: Dilutions. Purification of inorganic compounds I. Decantation, Filtration. Recrystallization. Purification of alum by recrystallization I.
• 9. Basic principles of calculations II: Dilutions. Purification of inorganic compounds I. Decantation, Filtration. Recrystallization. Purification of alum by recrystallization I.
• 10. Basic principles of calculations III: Crystallization. Purification of inorganic compounds II.: Destillation, Sublimation. Purification of alum II. Determination of % composition of contaminated calcium carbonate.
• 11. Basic principles of calculations III: Crystallization. Purification of inorganic compounds II.: Destillation, Sublimation. Purification of alum II. Determination of % composition of contaminated calcium carbonate.
• 12. Basic principles of calculations III: Crystallization. Purification of inorganic compounds II.: Destillation, Sublimation. Purification of alum II. Determination of % composition of contaminated calcium carbonate.
• 13. Basic principles of calculations IV: Stochiometry. Purification of inorganic compounds III. Desalination of water. Separation of iodine by sublimation. Separation of iodine by extraction.
• 14. Basic principles of calculations IV: Stochiometry. Purification of inorganic compounds III. Desalination of water. Separation of iodine by sublimation. Separation of iodine by extraction.
• 15. Basic principles of calculations IV: Stochiometry. Purification of inorganic compounds III. Desalination of water. Separation of iodine by sublimation. Separation of iodine by extraction.
• 16. Observation of thermal decompositions. Determination of melting point. Determination of boiling point.
• 17. Observation of thermal decompositions. Determination of melting point. Determination of boiling point.
• 18. Observation of thermal decompositions. Determination of melting point. Determination of boiling point.
• 19. Basic principles of chemical kinetics. Observation of reaction rates. Landolt-reaction. Oscillating reactions.
• 20. Basic principles of chemical kinetics. Observation of reaction rates. Landolt-reaction. Oscillating reactions.
• 21. Basic principles of chemical kinetics. Observation of reaction rates. Landolt-reaction. Oscillating reactions.
• 22. Electrolytic dissociation. Weak and strong electrolytes. Preparation of boric acid from borax I. Preparation of potassium dihydrogen phosphate I.
• 23. Electrolytic dissociation. Weak and strong electrolytes. Preparation of boric acid from borax I. Preparation of potassium dihydrogen phosphate I.
• 24. Electrolytic dissociation. Weak and strong electrolytes. Preparation of boric acid from borax I. Preparation of potassium dihydrogen phosphate I.
• 25. Acid-base equilibrium I. Buffers. Observation of hydrolysis of salts Demonstration of buffer capacity.
• 26. Acid-base equilibrium I. Buffers. Observation of hydrolysis of salts Demonstration of buffer capacity.
• 27. Acid-base equilibrium I. Buffers. Observation of hydrolysis of salts Demonstration of buffer capacity.
• 28. Acid-base equilibrium II. Acid-base theories. Hydrolysis of ions. Preparation of iron(II) ammonium sulfate.
• 29. Acid-base equilibrium II. Acid-base theories. Hydrolysis of ions. Preparation of iron(II) ammonium sulfate.
• 30. Acid-base equilibrium II. Acid-base theories. Hydrolysis of ions. Preparation of iron(II) ammonium sulfate.
• 31. Redox reactions I. Oxidation state. Important oxidizing and reducing agents. Observation of oxidation-reduction reactions.
• 32. Redox reactions I. Oxidation state. Important oxidizing and reducing agents. Observation of oxidation-reduction reactions.
• 33. Redox reactions I. Oxidation state. Important oxidizing and reducing agents. Observation of oxidation-reduction reactions.
• 34. Heterogenous equilibrium. Solubility calculations. Qualitative comparison of solubility products.
• 35. Heterogenous equilibrium. Solubility calculations. Qualitative comparison of solubility products.
• 36. Heterogenous equilibrium. Solubility calculations. Qualitative comparison of solubility products.
• 37. Redox reactions II. Electrodes, electrochemical cells, electrolysis. Preparation of copper(I) oxide.
• 38. Redox reactions II. Electrodes, electrochemical cells, electrolysis. Preparation of copper(I) oxide.
• 39. Redox reactions II. Electrodes, electrochemical cells, electrolysis. Preparation of copper(I) oxide.
• 40. Characterization of complexes. Stability constants. Preparation of potassium tris(oxalato) iron(III).
• 41. Characterization of complexes. Stability constants. Preparation of potassium tris(oxalato) iron(III).
• 42. Characterization of complexes. Stability constants. Preparation of potassium tris(oxalato) iron(III).

Seminare

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Ebbing D.D., Gammon S.D.: General Chemistry, 9th edition, Houghton Miffin Co., Boston, 2009

Vom Institut veröffentlichter Lehrstoff

Almási A., Kuzma M., Perjési P.: General and Inorganic Chemistry - Laboratory Techniques and Practices. University of Pécs, 2014. Electronic educational material,
Huber I: Inorganic Pharmaceutical Chemistry I. University of Pécs, 2019. Electronic educational material

Skript

Empfohlene Literatur

en.wikobooks.org/wiki/General_Chemistry

Voraussetzung zum Absolvieren des Semesters

Acknowledgement of the course is in accord with the Code of Studies and Examinations. Participation in the practices is obligatory. Maximum three absences can be accepted. Students have to write at least four mini-tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practical grade. Satisfactory (2) evaluation is the minimum requirement of acknowledgement of the semester.

Semesteranforderungen

Students have to write at least four mini-tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practical grade. Satisfactory (2) evaluation is the minimum requirement of acknowledgement of the semester.

Möglichkeiten zur Nachholung der Fehlzeiten

There is no opportunity to make up missed classes (lectures and practices).

Prüfungsfragen

N/A

Prüfer

Praktika, Seminarleiter/innen

• Dr. Fatemeh KENARI
• Dr. Almási Attila
• Dr. Perjési Pál
• Fülöpné Dr. Kiss Edit