Daten
Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2019-2020
Lehrbeauftragte/r
-
Dr. Péter JAKUS
assistant professor,
Department of Biochemistry and Medical Chemistry -
Semesterwochenstunden
Vorlesungen: 42
Praktika: 0
Seminare: 0
Insgesamt: 42
Fachangaben
- Kode des Kurses: OSA-BKD-T
- 3 kredit
- Dentistry
- Basic modul
- autumn
OSA-ORF-T completed , OSA-BEF-T completed
Vizsgakurzus:ja
Zahl der Kursteilnehmer für den Kurs:
min. 1 – max. 200
Thematik
The subject gives an overview of the molecular processes occurring in living organisms from two major aspects. On the one hand, following the subject -Introduction to Biochemistry&-, it describes the metabolism of the four major types of biomolecules (carbohydrates, lipids, amino ac ids/proteins and nucleotides /nucleic acids) along with the indirect enzymatic regulation of
these processes. On the other hand, built on the subject -Molecular Cell Biology&-, accounts for the molecular processes responsible for the transmission of information within the living organisms from molecular biological (DNA-RNA-protein-metabolite) as well as hormonal point of view. The subject lies down the foundations of the subjects Medical Biochemistry, Pharmacology and Clinical Chemistry.
Vorlesungen
- 1. Introduction - Dr. Jakus Péter Balázs
- 2. The pentose phosphate pathway - Dr. Veres Balázs
- 3. Gluconeogenesis in animal cells - Dr. Jakus Péter Balázs
- 4. Glycogen synthesis and degradation - Dr. Bognár Zita
- 5. Regulation of glycogen synthesis and degradation - Dr. Bognár Zita
- 6. Regulation and disorders of carbohydrate metabolism - Dr. Tapodi Antal
- 7. Fatty acid synthesis (with elongation and desaturation) - Dr. Tapodi Antal
- 8. Synthesis of complex lipids - Dr. Gallyas Ferenc
- 9. Structure and biological activities of steroids - Dr. Gallyas Ferenc
- 10. Synthesis of cholesterol and ketone bodies - Dr. Gallyas Ferenc
- 11. Regulation and disorders of lipid metabolism - Dr. Gallyas Ferenc
- 12. Amino acid metabolism; the fate of the amino group - Dr. Debreceni Balázs
- 13. Urea cycle - Dr. Debreceni Balázs
- 14. Amino acid metabolism; the fate of the carbon skeleton - Dr. Debreceni Balázs
- 15. Synthesis of non-essential amino acids - Dr. Debreceni Balázs
- 16. Enzymopathies of amino acid metabolism - Dr. Debreceni Balázs
- 17. Synthesis of biologically active molecules from amino acids - Dr. Debreceni Balázs
- 18. Synthesis of purine and pyrimidine nucleotides - Dr. Jakus Péter Balázs
- 19. Degradation of purine and pyrimidine nucleotides - Dr. Jakus Péter Balázs
- 20. Genes and chromosomes - Dr. Jakus Péter Balázs
- 21. DNA replication - Dr. Jakus Péter Balázs
- 22. DNA repair - Dr. Jakus Péter Balázs
- 23. RNA metabolism 1 - Dr. Veres Balázs
- 24. RNA metabolism 2 - Dr. Veres Balázs
- 25. Short RNA molecules - Dr. Veres Balázs
- 26. Retroviruses - Dr. Veres Balázs
- 27. Protein synthesis 1. Participants and mechanism - Dr. Jakus Péter Balázs
- 28. Protein synthesis 2. Regulation, posttranslational modifications - Dr. Berente Zoltán
- 29. Protein folding, chaperones - Dr. Berente Zoltán
- 30. Protein targeting and vesicular transport of proteins - Dr. Berente Zoltán
- 31. Intracellular proteolysis - Dr. Jakus Péter Balázs
- 32. Regulation of gene expression 1 - Dr. Jakus Péter Balázs
- 33. Regulation of gene expression 2 - Dr. Sümegi Balázs
- 34. Mitochondrial protein synthesis, mitochondrial genome - Dr. Sümegi Balázs
- 35. Recombinant DNA technologies - Dr. Jakus Péter Balázs
- 36. Hormones 1 - Dr. Tapodi Antal
- 37. Hormones 2 - Dr. Tapodi Antal
- 38. Cell signalling and kinases I - Dr. Veres Balázs
- 39. Cell signalling and kinases II - Dr. Jakus Péter Balázs
- 40. Cell signalling, CO and NO as signals, transcription factors - Dr. Jakus Péter Balázs
- 41. Water soluble vitamins - Dr. Jakus Péter Balázs
- 42. Lipid soluble vitamins - Dr. Jakus Péter Balázs
Praktika
Seminare
Materialien zum Aneignen des Lehrstoffes
Obligatorische Literatur
Nelson, Cox: Lehninger Principles of Biochemistry, 6th edition, W.H. Freeman, 2013
Vom Institut veröffentlichter Lehrstoff
Skript
Nagy V.: Experiments is Med. Chem. lab manual, 2017
Nagy V.: Introduction to biochemistry lab manual 2017
Empfohlene Literatur
Berg, Tymoczko, Stryer: Biochemistry, 7th edition, W.H. Freeman, 2012.
Devlin: Textbook of Biochemistry with Clinical Correlations 7th edition, Wiley, 2010.
Voraussetzung zum Absolvieren des Semesters
Maximum of 15 % absence allowed
Semesteranforderungen
It is obligatory to visit the lectures.
Möglichkeiten zur Nachholung der Fehlzeiten
Non
Prüfungsfragen
The exam based on the lectures and labs of the previous semesters and the lectures of the actual semester.
After entering into the website of the UNI: http://aok.pte.hu/en/egyseg/oktatasianyagok/20
Prüfer
- Dr. Bognár Zita
- Dr. Jakus Péter Balázs
- Dr. Takátsy Anikó
- Dr. Tapodi Antal