Biochemistry for Dentistry Students

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2019-2020

Tematika

The subject gives an overview of the molecular processes occurring in living organisms from two major aspects. On the one hand, following the subject -Introduction to Biochemistry&-, it describes the metabolism of the four major types of biomolecules (carbohydrates, lipids, amino ac ids/proteins and nucleotides /nucleic acids) along with the indirect enzymatic regulation of
these processes. On the other hand, built on the subject -Molecular Cell Biology&-, accounts for the molecular processes responsible for the transmission of information within the living organisms from molecular biological (DNA-RNA-protein-metabolite) as well as hormonal point of view. The subject lies down the foundations of the subjects Medical Biochemistry, Pharmacology and Clinical Chemistry.

Előadások

• 1. Introduction - Dr. Jakus Péter Balázs
• 2. The pentose phosphate pathway - Dr. Veres Balázs
• 3. Gluconeogenesis in animal cells - Dr. Jakus Péter Balázs
• 4. Glycogen synthesis and degradation - Dr. Bognár Zita
• 5. Regulation of glycogen synthesis and degradation - Dr. Bognár Zita
• 6. Regulation and disorders of carbohydrate metabolism - Dr. Tapodi Antal
• 7. Fatty acid synthesis (with elongation and desaturation) - Dr. Tapodi Antal
• 8. Synthesis of complex lipids - Dr. Gallyas Ferenc
• 9. Structure and biological activities of steroids - Dr. Gallyas Ferenc
• 10. Synthesis of cholesterol and ketone bodies - Dr. Gallyas Ferenc
• 11. Regulation and disorders of lipid metabolism - Dr. Gallyas Ferenc
• 12. Amino acid metabolism; the fate of the amino group - Dr. Debreceni Balázs
• 13. Urea cycle - Dr. Debreceni Balázs
• 14. Amino acid metabolism; the fate of the carbon skeleton - Dr. Debreceni Balázs
• 15. Synthesis of non-essential amino acids - Dr. Debreceni Balázs
• 16. Enzymopathies of amino acid metabolism - Dr. Debreceni Balázs
• 17. Synthesis of biologically active molecules from amino acids - Dr. Debreceni Balázs
• 18. Synthesis of purine and pyrimidine nucleotides - Dr. Jakus Péter Balázs
• 19. Degradation of purine and pyrimidine nucleotides - Dr. Jakus Péter Balázs
• 20. Genes and chromosomes - Dr. Jakus Péter Balázs
• 21. DNA replication - Dr. Jakus Péter Balázs
• 22. DNA repair - Dr. Jakus Péter Balázs
• 23. RNA metabolism 1 - Dr. Veres Balázs
• 24. RNA metabolism 2 - Dr. Veres Balázs
• 25. Short RNA molecules - Dr. Veres Balázs
• 26. Retroviruses - Dr. Veres Balázs
• 27. Protein synthesis 1. Participants and mechanism - Dr. Jakus Péter Balázs
• 28. Protein synthesis 2. Regulation, posttranslational modifications - Dr. Berente Zoltán
• 29. Protein folding, chaperones - Dr. Berente Zoltán
• 30. Protein targeting and vesicular transport of proteins - Dr. Berente Zoltán
• 31. Intracellular proteolysis - Dr. Jakus Péter Balázs
• 32. Regulation of gene expression 1 - Dr. Jakus Péter Balázs
• 33. Regulation of gene expression 2 - Dr. Sümegi Balázs
• 34. Mitochondrial protein synthesis, mitochondrial genome - Dr. Sümegi Balázs
• 35. Recombinant DNA technologies - Dr. Jakus Péter Balázs
• 36. Hormones 1 - Dr. Tapodi Antal
• 37. Hormones 2 - Dr. Tapodi Antal
• 38. Cell signalling and kinases I - Dr. Veres Balázs
• 39. Cell signalling and kinases II - Dr. Jakus Péter Balázs
• 40. Cell signalling, CO and NO as signals, transcription factors - Dr. Jakus Péter Balázs
• 41. Water soluble vitamins - Dr. Jakus Péter Balázs
• 42. Lipid soluble vitamins - Dr. Jakus Péter Balázs

Gyakorlatok

Szemináriumok

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

Nelson, Cox: Lehninger Principles of Biochemistry, 6th edition, W.H. Freeman, 2013

Saját oktatási anyag

Jegyzet

Nagy V.: Experiments is Med. Chem. lab manual, 2017
Nagy V.: Introduction to biochemistry lab manual 2017

Ajánlott irodalom

Berg, Tymoczko, Stryer: Biochemistry, 7th edition, W.H. Freeman, 2012.
Devlin: Textbook of Biochemistry with Clinical Correlations 7th edition, Wiley, 2010.

A félév elfogadásának feltételei

Maximum of 15 % absence allowed

Félévközi ellenőrzések

It is obligatory to visit the lectures.

Távolmaradás pótlásának lehetőségei

Non

Vizsgakérdések

The exam based on the lectures and labs of the previous semesters and the lectures of the actual semester.
After entering into the website of the UNI: http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Vizsgáztatók

• Dr. Bognár Zita
• Dr. Jakus Péter Balázs
• Dr. Takátsy Anikó
• Dr. Tapodi Antal

Gyakorlatok, szemináriumok oktatói