Pharmacology for Dentistry Students 1

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2024-2025

Tematika

The general aim of the subject is to provide the dentistry students with all the basic information in pharmacology necessary to understand the actions of drugs and the clinical pharmacotherapy. Pharmacology can be defined as the study of the manner in which the function of living systems is affected by chemical agents. Therefore, the students should be familiar with the basic knowledge of the physiological, pathophysiological and biochemical background of the pharmacological and therapeutic approaches. On the other hand, drug therapy is closely related to the clinical aspects of diseases.

The following topics will be dealt with. Definitions, prescription writing, drug development, drug formulations. General aspects of mechanisms of drug actions: characterization of drug-receptor interactions, mechanisms of drug antagonism, signal transduction mechanisms of drug receptors. General and quantitative aspects of pharmacokinetics: absorption, distribution and elimination of drugs. Pharmacology of the autonomic nervous system. Local anaesthetics.

Cardiovascular pharmacology: drugs used to treat congestive heart failure, antianginal, antiarrhythmic, antihypertensive drugs, diuretics, calcium channel blockers, drugs acting on the renin-angiotensin-aldosterone system. Drugs affecting haemostasis, haematopoesis and hyperlipoproteinaemias. Pharmacology of histamine, serotonin.

Előadások

• 1. Introduction to pharmacology, drug development - Sándor Zoltán (1968, Farmakológia)
• 2. Basic mechanisms of drug effects - Sándor Zoltán (1968, Farmakológia)
• 3. Signal transduction - Sándor Zoltán (1968, Farmakológia)
• 4.

  Characteristics of the agonist-receptor interaction I.

  - Al-Omari Ammar Abdallah Khalaf
• 5.

  Characteristics of the agonist-receptor interaction II.

  - Al-Omari Ammar Abdallah Khalaf
• 6.

  Antagonism, tachyphylaxis and tolerance

  - Al-Omari Ammar Abdallah Khalaf
• 7. Absorption, distribution, biotransformation and excretion - Gasznerné Kormos Viktória
• 8. Quantitative pharmacokinetics I. - Gasznerné Kormos Viktória
• 9. Quantitative pharmacokinetics II. - Gasznerné Kormos Viktória
• 10.

  Introduction to the pharmacology of the autonomic nervous system

  - Al-Omari Ammar Abdallah Khalaf
• 11.

  Cholinerg agonists, cholinesterase inhibitors

  - Al-Omari Ammar Abdallah Khalaf
• 12.

  Muscarine receptor antagonists

  - Al-Omari Ammar Abdallah Khalaf
• 13. Drugs acting on the synthesis, storage, release and elimination of catecholamines - Gasznerné Kormos Viktória
• 14. Adrenergic receptor agonists - Gasznerné Kormos Viktória
• 15. Adrenergic receptor antagonists - Gasznerné Kormos Viktória
• 16.

  Local anaesthetics I.

  - Al-Omari Ammar Abdallah Khalaf
• 17.

  Local anaesthetics II.

  - Al-Omari Ammar Abdallah Khalaf
• 18.

  Calcium channel blockers

  - Al-Omari Ammar Abdallah Khalaf
• 19. Drugs acting on the renin-angiotensin system - Sándor Zoltán (1968, Farmakológia)
• 20. Diuretics - Sándor Zoltán (1968, Farmakológia)
• 21. Therapy of congestive heart failure - Sándor Zoltán (1968, Farmakológia)
• 22.

  Antianginal drugs

  - Sándor Zoltán (1968, Farmakológia)
• 23.

  Pharmacotherapy of hypertension

  - Sándor Zoltán (1968, Farmakológia)
• 24.

  Antiarrhythmic drugs

  - Sándor Zoltán (1968, Farmakológia)
• 25. Eicosanoids - Gasznerné Kormos Viktória
• 26. Drugs acting on smooth muscle - Gasznerné Kormos Viktória
• 27. Pharmacotherapy of hyperlipoproteinemias - Gasznerné Kormos Viktória
• 28.

  Drugs influencing haemostasis I.

  - Al-Omari Ammar Abdallah Khalaf
• 29.

  Drugs influencing haemostasis II.

  - Al-Omari Ammar Abdallah Khalaf
• 30.

  Drugs influencing haemostasis III.

  - Al-Omari Ammar Abdallah Khalaf
• 31. Drugs influencing haematopoiesis - Gasznerné Kormos Viktória
• 32. Drugs acting on the respiratory system I. - Gasznerné Kormos Viktória
• 33. Drugs acting on the respiratory system II. - Gasznerné Kormos Viktória
• 34. Peripheral muscle relaxants - Sándor Zoltán (1968, Farmakológia)
• 35. Histamine and histamine receptor antagonists - Sándor Zoltán (1968, Farmakológia)
• 36. Serotonin and 5-HT receptor agonists and antagonists - Sándor Zoltán (1968, Farmakológia)
• 37. Drug formulations I. - Sándor Zoltán (1968, Farmakológia)
• 38. Drug formulations II. - Sándor Zoltán (1968, Farmakológia)
• 39. Drug formulations III. - Sándor Zoltán (1968, Farmakológia)
• 40. Consultation I. - Sándor Zoltán (1968, Farmakológia)
• 41. Consultation II. - Sándor Zoltán (1968, Farmakológia)
• 42. Test writing - Sándor Zoltán (1968, Farmakológia)

Gyakorlatok

Szemináriumok

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

Rang, Dale,B. Ritter, Moore: Pharmacology, 8th edition, Elsevier Churchill Livingstone, 2015.

G. Katzung (ed.): Basic and Clinical Pharmacology, 12th edition, Lange Medical Books/McGraw-Hill, 2012.

Saját oktatási anyag

Intranet. Department of Pharmacology and Pharmacotherapy. Educational materials.

Neptun Meet Street

Jegyzet

Ajánlott irodalom

A félév elfogadásának feltételei

For the semester to be accepted students are allowed to be absent from maximum 9 lectures.

Félévközi ellenőrzések

There is no mid-term examination.

Távolmaradás pótlásának lehetőségei

Not possible

Vizsgakérdések

1. Drug development

2. Basic mechanisms of drug actions, signaling processes

3. Characterization of the agonist-receptor interaction

4. Antagonism, tachyphylaxis and tolerance

5. Absorption, distribution,

6. Biotransformation and secretion

7. Pharmacokinetic parameters

8. Cholinergic agonists, cholinesterase inhibitors

9. Muscarinic receptor antagonists

10. Drugs affecting the synthesis, release and elimination of catecholamines

11. Adrenergic receptor agonists

12. Adrenergic receptor antagonists

13. Local anesthetics

14. Calcium channel blockers

15. Agents acting on the renin-angiotensin-aldosterone system

16. Diuretics

17. Treatment of congestive heart failure

18. Antianginal drugs

19. Treatment of high blood pressure

20. Antiarrhythmic drugs

21. Eicosanoids and smooth muscle agents

22. Agents acting on hyperlipoproteinemias

23. Anticoagulants, antiplatelet agents

24. Fibrinolytics, antifibrinolytics, hemostatic agents

25. Agents affecting hematopoiesis

26. Agents affecting the respiratory system

27. Peripheral muscle relaxants

28. Histamine and histamine receptor antagonists

29. Serotonin, 5-HT-receptor agonists and antagonists, migraine therapy

30. Basics of fluid therapy

The condition for passing the exam is at least satisfactory completion of the written test based on the listed topics.

Vizsgáztatók

• Gasznerné Kormos Viktória
• Sándor Zoltán (1968, Farmakológia)

Gyakorlatok, szemináriumok oktatói

• Al-Omari Ammar Abdallah Khalaf
• Gasznerné Kormos Viktória
• Sándor Zoltán (1968, Farmakológia)