Central Regulation of Feeding and Metabolism. New Approaches

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2023-2024

Tematika

The high incidence and costs of eating and metabolic disorders make it indispensable to experimentally test new theoretical considerations, and to employ their conclusive results in basically new clinical protocols. Students at early stage of their studies are, thus, encouraged to familiarize with new theoretical aspects and experimental findings.
Neural and humoral mechanisms in the central feeding control and metabolic regulation. Body weight control in health and disease. Peripheral and central taste information processing; gustation in the central regulation of food and fluid intake. Obesity, diabetes mellitus and the metabolic syndrome: New interpretations.

Előadások

• 1. Physiological significance of food and fluid intake, and metabolism. Homeostasis, motivation. - Mintál Kitti
• 2. Neuronal and humoral factors in the central regulation of homeostatic functions: brain centers, neurotransmitter pathways, neuropeptides. I - Mintál Kitti
• 3. Neuronal and humoral factors in the central regulation of homeostatic functions: brain centers, neurotransmitter pathways, neuropeptides. II - Mintál Kitti
• 4. Exogenous chemosensory modalities. Physiologic roles of gustation. - Dr. László Bettina Réka
• 5. Central taste pathways. - Dr. László Bettina Réka
• 6. Taste preference, taste aversion, palatability, flavour. - Dr. László Bettina Réka
• 7. The glucose-monitoring (GM) neural network. I - Hormay Edina Emőke
• 8. The glucose-monitoring (GM) neural network. II - Hormay Edina Emőke
• 9. Eating and metabolic disorders: obesity, anorexia nervosa, diabetes mellitus, metabolic syndrome. I - Hormay Edina Emőke
• 10. Eating and metabolic disorders: obesity, anorexia nervosa, diabetes mellitus, metabolic syndrome. II - Hormay Edina Emőke
• 11. Feeding and metabolic disorders: disturbance of the GM system? - Hormay Edina Emőke
• 12. Our research results in the field of central regulation of feeding and metabolism. - Dr. László Bettina Réka

Gyakorlatok

Szemináriumok

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

Guyton & Hall: Textbook of Medical Physiology, Saunders

Saját oktatási anyag

The ppt file of the lectures.

Jegyzet

Ajánlott irodalom

Williams and Pickup: Handbook of Diabetes, Blackwell
Doty: Handbook of Olfaction and Gustation, Marcel Dekker

A félév elfogadásának feltételei

Maximum of 15 % absence allowed

Félévközi ellenőrzések

Written mid-semester test.

Távolmaradás pótlásának lehetőségei

There is no.

Vizsgakérdések

1. Feeding (hunger) and satiety centers; feeding (hunger) and satiety neural pathways.
2. Orexigenic and anorexigenic neuromodulator factors (list up at least 3 of each).
3. The two major neuron types of the hypothalamic arcuate nucleus (with respect to feeding); their modulation by insulin, leptin, and ghrelin.
4. Key structures of the central glucose-monitoring neuronal network (list up at least 4 of them).
5. Consequences of selective destruction of central GM neurons (name of the toxic agent, and its effects).

Vizsgáztatók

Gyakorlatok, szemináriumok oktatói