Molecular Diagnostics

Daten

Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2024-2025

Thematik

The modern laboratory diagnostic methods, including molecular and immunological techniques will be discussed.

Vorlesungen

• 1. Basic terms of immunologic detection methods. Antigen-antibody reactions. Sensitivity, specificity of antigen-antibody reactions. Immunoassay types. - Berki Timea
• 2. Multiplex detection methods. Cytokine, chemokine detection methods. Biomarkers. - Berki Timea
• 3. Immunserological methods, autoantibody testing, detection of allergen specific IgE. - Simon Diána
• 4. The most frequently used analytical methods. Preanalytics, postanalytics. Laboratory automation. - Nagy Tamás
• 5. Plasma protein testing methods and evaluation of results in laboratory medicine. - Nagy Tamás
• 6. HLA and disease assotiation, methods for HLA-typing, HLA-B27 typing. Phage display. - Simon Diána
• 7. Molecular genetics in laboratory medicine - Gombos Katalin
• 8. Methods for locus-specific and genome-wide epigenetic studies - Rauch Tibor Attila
• 9. Genetic diagnostics of Mendelian disorders - Berenténé Bene Judit Ágnes
• 10. DNA and RNA sequencing technologies and applications - Urbán Péter
• 11. Molecular diagnostics of microbes. Nucleic Acid-based Techniques (NATs) in pathogen detection. - Pankovics Péter
• 12. Molecular diagnostics of microbes. Molecular typing methods in multi-drug resistant bacterial outbreak investigations. - Pál Ágnes Mária (Sonnevend)
• 13. Cytogenetics in oncological diagnostics - Kajtár Béla
• 14. Molecular methods in precision oncology - Kajtár Béla

Praktika

Seminare

• 1. Antigen-antibody reactions. Immunoassay types.
• 2. Multiplex detection methods
• 3. Autoantibody detection methods. Diagnostics of systemic autoimmune diseases. Laboratory diagnostics of allergy.
• 4. Immunchemistry laboratory equipments, detection methods.
• 5. Protein chemistry
• 6. HLA and diseases. HlA typing. Phage display libraries.
• 7. Genetics and molecular biology in laboratory medicine
• 8. Methods for epigenetic studies
• 9. Basic terms of genetic diagnostics. Genetic diagnostics of Mendelian disorders.
• 10. DNA and RNA sequencing technologies
• 11. Molecular diagnostics of microbes.
• 12. Molecular diagnostics of microbes
• 13. Cytogenetics in oncological diagnostics
• 14. Molecular testing in oncology

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Vom Institut veröffentlichter Lehrstoff

www.medbiotech.com

Skript

Empfohlene Literatur

Voraussetzung zum Absolvieren des Semesters

Attendance at lectures and active participation in seminars.

Semesteranforderungen

-

Möglichkeiten zur Nachholung der Fehlzeiten

None

Prüfungsfragen

Written test exam with questions provided by the lecturers, if necessary in online format (moodle).

Prüfer

• Simon Diána

Praktika, Seminarleiter/innen

• Berenténé Bene Judit Ágnes
• Berki Timea
• Gombos Katalin
• Kajtár Béla
• Nagy Tamás
• Pál Ágnes Mária (Sonnevend)
• Pankovics Péter
• Rauch Tibor Attila
• Simon Diána
• Urbán Péter