Central Regulation of Feeding and Metabolism. New Approaches

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2020-2021

Tematika

The high incidence and costs of eating and metabolic disorders make it indispensable to experimentally test new theoretical considerations, and to employ their conclusive results in basically new clinical protocols. Students at early stage of their studies are, thus, encouraged to familiarize with new theoretical aspects and experimental findings.
Neural and humoral mechanisms in the central feeding control and metabolic regulation. Body weight control in health and disease. Peripheral and central taste information processing; gustation in the central regulation of food and fluid intake. Obesity, diabetes mellitus and the metabolic syndrome: New interpretations.

Előadások

• 1. Physiological significance of food and fluid intake, and metabolism. Homeostasis, motivation. - Dr. Karádi Zoltán
• 2. Neuronal and humoral factors in the central regulation of homeostatic functions: brain centers, neurotransmitter pathways, neuropeptides. I - Dr. Karádi Zoltán
• 3. Neuronal and humoral factors in the central regulation of homeostatic functions: brain centers, neurotransmitter pathways, neuropeptides. II - Dr. Karádi Zoltán
• 4. Neuronal and humoral factors in the central regulation of homeostatic functions: brain centers, neurotransmitter pathways, neuropeptides. III - Dr. Karádi Zoltán
• 5. Exogenous chemosensory modalities. Physiologic roles of gustation. - Dr. Karádi Zoltán
• 6. Central taste pathways, "labeled lines", neurons. - Dr. Karádi Zoltán
• 7. Taste preference, taste aversion, palatability, flavour. - Dr. Karádi Zoltán
• 8. The glucose-monitoring (GM) neural network. I - Dr. Karádi Zoltán
• 9. The glucose-monitoring (GM) neural network. II - Dr. Karádi Zoltán
• 10. Eating and metabolic disorders: obesity, anorexia nervosa, diabetes mellitus, metabolic syndrome. I - Dr. Karádi Zoltán
• 11. Eating and metabolic disorders: obesity, anorexia nervosa, diabetes mellitus, metabolic syndrome. II - Dr. Karádi Zoltán
• 12. Feeding and metabolic disorders: disturbance of the GM system? - Dr. Karádi Zoltán

Gyakorlatok

Szemináriumok

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

Guyton & Hall: Textbook of Medical Physiology, Saunders

Saját oktatási anyag

Jegyzet

Ajánlott irodalom

Williams and Pickup: Handbook of Diabetes, Blackwell
Doty: Handbook of Olfaction and Gustation, Marcel Dekker

A félév elfogadásának feltételei

According to general regulations

Félévközi ellenőrzések

Individual oral mid-semester test.

Távolmaradás pótlásának lehetőségei

Individually discussed

Vizsgakérdések

1. Feeding (hunger) and satiety centers; feeding (hunger) and satiety neural pathways.
2. Orexigenic and anorexigenic neuromodulator factors (list up at least 3 of each).
3. The two major neuron types of the hypothalamic arcuate nucleus (with respect to feeding); their modulation by insulin, leptin, and ghrelin.
4. Key structures of the central glucose-monitoring neuronal network (list up at least 4 of them).
5. Consequences of selective destruction of central GM neurons (name of the toxic agent, and its effects).

Vizsgáztatók

Gyakorlatok, szemináriumok oktatói